2024
The Role of Angiopoietins in Cardiovascular Outcomes of Kidney Transplant Recipients: An Ancillary Study from the FAVORIT
Gendy N, Brown L, Staunton M, Garg K, Hernandez Garcilazo N, Qian L, Yamamoto Y, Ugwuowo U, Obeid W, Al-Qusairi L, Bostom A, Mansour S. The Role of Angiopoietins in Cardiovascular Outcomes of Kidney Transplant Recipients: An Ancillary Study from the FAVORIT. American Journal Of Nephrology 2024, 55: 597-606. PMID: 38735283, PMCID: PMC11444892, DOI: 10.1159/000538878.Peer-Reviewed Original ResearchKidney transplant recipientsRisk of cardiovascular diseaseGraft failureCardiovascular disease developmentAngpt-2Cardiovascular diseaseIncreased risk of future CVDAncillary studiesClinical variablesCare of kidney transplant recipientsIncreased riskRisk of future CVDUrine albumin-to-creatinine ratioDonor kidney transplant recipientsAlbumin-to-creatinine ratioIncreased risk of cardiovascular diseaseFuture cardiovascular diseaseImproves prediction of cardiovascular diseaseTransplant-related variablesAssociated with outcomeParticipants' median ageMitigate CVD riskMedian ageTransplant recipientsMedian time
2019
Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery
Moledina DG, Mansour SG, Jia Y, Obeid W, Thiessen-Philbrook H, Koyner JL, McArthur E, Garg AX, Wilson FP, Shlipak MG, Coca SG, Parikh CR, Consortium T. Association of T Cell–Derived Inflammatory Cytokines With Acute Kidney Injury and Mortality After Cardiac Surgery. Kidney International Reports 2019, 4: 1689-1697. PMID: 31844805, PMCID: PMC6895592, DOI: 10.1016/j.ekir.2019.09.003.Peer-Reviewed Original ResearchAcute kidney injuryIschemia-reperfusion injuryCardiac surgeryKidney injuryIL-13IL-4Higher oddsT cell-derived inflammatory cytokinesPostoperative acute kidney injuryRenal ischemia-reperfusion injuryTh2 biomarkersObservational cohortPreoperative levelsT helperTh2 pathwayClinical outcomesTh2 cytokinesClinical variablesInflammatory cytokinesIndependent associationPlasma biomarkersTh2 cellsSurgeryAnimal modelsMortality