2020
Long-term effects of moderate physical exercise during early childhood on insulin sensitivity in rats during adulthood
Pereira R, Muñoz V, Anaruma C, Gaspar R, Gaspar R, Ropelle E, Cintra D, da Silva A, Pauli J, de Moura L. Long-term effects of moderate physical exercise during early childhood on insulin sensitivity in rats during adulthood. Revista Brasileira De Educação Física E Esporte 2020, 34: 227-236. DOI: 10.11606/1807-5509202000020227.Peer-Reviewed Original ResearchModerate physical exerciseInsulin sensitivityPhysical exerciseGlycogen storesLipogenic activityGlucose uptakePancreatic insulin levelsDays/weekLower body weight gainPhysical exercise protocolBody weight gainHours/dayDays of ageHOMA-IRInsulin levelsInsulin resistanceMetabolic healthExercise protocolSwimming exerciseWistar ratsLong-term effectsBody fatPancreatic insulinAdipose tissueAnaerobic threshold
2019
Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice
Nakandakari S, Muñoz V, Kuga G, Gaspar R, Sant'Ana M, Pavan I, da Silva L, Morelli A, Simabuco F, da Silva A, de Moura L, Ropelle E, Cintra D, Pauli J. Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice. Brain Behavior And Immunity 2019, 79: 284-293. PMID: 30797044, DOI: 10.1016/j.bbi.2019.02.016.Peer-Reviewed Original ResearchConceptsHigh-fat dietYoung miceShort-term HFD feedingMice fed high-fat dietFed high-fat dietHippocampus of miceER stressDisease developmentShort-term consumptionAlzheimer's disease developmentPotential molecular mechanismsHOMA-IRHFD feedingAD markersMicroglial cellsAD pathogenesisRisk factorsInflammatory signalsDiet modulatesΒ-amyloidCleaved caspase3HippocampusApoptosis markersHigh expressionMice