Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
Agarwal B, Swaroop P, Protiva P, Raj S, Shirin H, Holt P. Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells. Apoptosis 2003, 8: 649-654. PMID: 14739610, DOI: 10.1023/a:1026199929747.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsApoptosisColonic NeoplasmsCurcuminCyclooxygenase 2IsoenzymesProstaglandin-Endoperoxide SynthasesPyrazolesSulfonamidesSulindacConceptsHCT116 cellsHT29 cellsProtein expressionColon cancer cellsColon cancer cell linesCell numberCOX-2 protein expressionCancer cell linesApoptosisProtein levelsCancer cellsCell linesExpressionSelective inhibitorHT29CellsFlow cytometryCOX-2 protein levelsInhibitorsCOX-2COX-2 expressionHCT116High levelsRoleΜM