2022
Early infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia
I U U, Adeiza M, Ideh R, Ogbuagu O. Early infant diagnosis of HIV infection at the John F. Kennedy Medical Center, Monrovia, Liberia. HIV Research & Clinical Practice 2022, 23: 136-140. PMID: 35703420, DOI: 10.1080/25787489.2022.2086093.Peer-Reviewed Original ResearchMeSH KeywordsChildCross-Sectional StudiesFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLiberiaMalePregnancyRetrospective StudiesConceptsVertical transmission rateVertical transmissionMTCT programmePCR testingEarly infant diagnosis programHIV DNA PCR testingRetrospective cross-sectional analysisDemographics of mothersDNA PCR testingExpansion of preventionHIV DNA PCRHIV-positive childrenHIV-positive mothersInfectious disease clinicPost-exposure prophylaxisEarly neonatal deathNew HIV infectionsMode of deliveryLogistic regression analysisBinomial logistic regression analysisCross-sectional analysisPMTCT programmeCaesarean sectionExclusive breastfeedingDisease clinic
2021
High HIV Detection in a Tertiary Facility in Liberia: Implications and Opportunities
Ogbuagu O, Wachekwa I, Yasin F, Nuta C, Donato S, Toomey J, Adeiza M, Barakat LA. High HIV Detection in a Tertiary Facility in Liberia: Implications and Opportunities. Annals Of Global Health 2021, 87: 117. PMID: 34900617, PMCID: PMC8622250, DOI: 10.5334/aogh.3243.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildFemaleHIV InfectionsHumansLiberiaPregnancyPregnancy Complications, InfectiousPrevalenceRetrospective StudiesYoung AdultConceptsHIV testing dataNon-pregnant individualsHIV detection rateTertiary facilityPrevention interventionsJohn F. Kennedy Medical CenterHospital-based retrospective analysisSignificant public health challengeStudy periodAnnual diagnosis ratePre-exposure prophylaxisPositive HIV testLarge tertiary hospitalCase detection ratePublic health challengeYears of ageNational prevalence estimatesDetection rateHIV/AIDSAntenatal clinicHIV testHIV testingTertiary hospitalPregnant womenUNAIDS 95
2018
Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus–infected patients compared to non-nucleoside and protease inhibitor–based regimens in a real-world clinical setting
Jacobson K, Ogbuagu O. Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus–infected patients compared to non-nucleoside and protease inhibitor–based regimens in a real-world clinical setting. Medicine 2018, 97: e13016. PMID: 30412140, PMCID: PMC6221636, DOI: 10.1097/md.0000000000013016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsFemaleHIV InfectionsHumansMaleMiddle AgedRetrospective StudiesViral LoadConceptsVirologic suppressionInhibitor-based regimensAntiretroviral therapyMedian timeIntegrase strand transfer inhibitor (INSTI) classHuman immunodeficiency virus-infected patientsIntegrase inhibitor-based regimensMedian baseline CD4 countHuman immunodeficiency virus (HIV) patientsRetrospective single-center studyClinical settingProtease inhibitorsReal-world clinical settingART regimen typeVirologic suppression ratesBaseline CD4 countSingle-center studyVirus-infected patientsCells/μLCopies/mLStudy inclusion criteriaNon-nucleoside reverseRoutine clinical settingLower median timeART initiation