Human β2‐adrenergic receptor polymorphisms: No association with essential hypertension in black or white Americans
Xie H, Stein C, Kim R, Gainer J, Sofowora G, Dishy V, Brown N, Goree R, Haines J, Wood A. Human β2‐adrenergic receptor polymorphisms: No association with essential hypertension in black or white Americans. Clinical Pharmacology & Therapeutics 2000, 67: 670-675. PMID: 10872649, DOI: 10.1067/mcp.2000.106293.Peer-Reviewed Original ResearchConceptsHypertensive subjectsEssential hypertensionGlu27 alleleBeta2-adrenergic receptor genotypesBeta2-adrenergic receptor polymorphismsWhite subjectsReceptor variantsBeta2-adrenergic receptor geneNormotensive white subjectsPresence of hypertensionBlack subjectsHomozygous genotypeBeta2-adrenergic receptorCommon genetic polymorphismsHypertensive groupNormotensive subjectsBlood pressurePopulation-based case-control association studiesVascular responsesCase-control association studyReceptor polymorphismsReceptor genotypeHypertensionReceptor responsesHuman beta2-adrenergic receptor