2000
Thrombospondin Type 1 Repeats Interact with Matrix Metalloproteinase 2 REGULATION OF METALLOPROTEINASE ACTIVITY*
Bein K, Simons M. Thrombospondin Type 1 Repeats Interact with Matrix Metalloproteinase 2 REGULATION OF METALLOPROTEINASE ACTIVITY*. Journal Of Biological Chemistry 2000, 275: 32167-32173. PMID: 10900205, DOI: 10.1074/jbc.m003834200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBinding SitesBlotting, WesternCatalytic DomainCattleCell LineCollagenasesEnzyme ActivationEnzyme PrecursorsHumansMatrix Metalloproteinase 2Matrix Metalloproteinase 3Matrix Metalloproteinase 9Matrix Metalloproteinase InhibitorsPeptide FragmentsPrecipitin TestsProperdinProtein BindingProtein Structure, TertiaryRepetitive Sequences, Amino AcidSaccharomyces cerevisiaeThrombinThrombospondin 1ThrombospondinsTwo-Hybrid System TechniquesConceptsIntact thrombospondin-1Thrombospondin-1Ability of TSP1Matrix metalloproteinase-2Two-hybrid systemType 1 repeatsCatalytic domainCDNA clonesProtein interactionsThrombospondin type 1Terminal regionGelatin-binding domainAmino acidsInhibitors of angiogenesisCatalytic centerMMP activityTSP2Western blottingProteinTissue cultureClonesMapping sitesMetalloproteinase activityActivationMetalloproteinase-2
1998
Myb-dependent Regulation of Thrombospondin 2 Expression ROLE OF mRNA STABILITY*
Bein K, Ware J, Simons M. Myb-dependent Regulation of Thrombospondin 2 Expression ROLE OF mRNA STABILITY*. Journal Of Biological Chemistry 1998, 273: 21423-21429. PMID: 9694906, DOI: 10.1074/jbc.273.33.21423.Peer-Reviewed Original ResearchConceptsNIH 3T3 cellsC-MybWild-type NIH 3T3 cellsTranscription factor c-MybEndogenous target genesPost-transcriptional mechanismsPromoter-reporter assaysMRNA stability studiesDifferential display analysisSimilar transcriptional levelsTSP-2 expressionV-SrcHomology searchCDNA endsGene productsTarget genesTranscriptional levelMRNA stabilityV-mycCell cycleTSP-1C-JunHematopoietic cellsDNA probesHomologous products