1996
Direct Vasomotor Effects of Isoflurane in Subepicardial Resistance Vessels from Collateral-dependent and Normal Coronary Circulation of Pigs
Park K, Lowenstein E, Dai H, Lopez J, Stamler A, Simons M, Sellke F. Direct Vasomotor Effects of Isoflurane in Subepicardial Resistance Vessels from Collateral-dependent and Normal Coronary Circulation of Pigs. Anesthesiology 1996, 85: 584-591.. PMID: 8853089, DOI: 10.1097/00000542-199609000-00018.Peer-Reviewed Original ResearchConceptsDirect vasomotor effectResistance vesselsVasomotor effectsNormal vesselsCoronary arteryEndothelin-1Sodium nitroprussideEndothelium-independent dilator sodium nitroprussideNormal coronary circulationResistance coronary arteriesCoronary resistance vesselsChronic coronary occlusionConcentration-dependent constrictionThromboxane analog U46619 1 microMLeft circumflex arteryRapid atrial pacingMyocardial blood flowEndothelial dysfunctionVasoconstrictive effectAtrial pacingCircumflex arteryCoronary occlusionConstrictive effectOccluder placementCoronary circulation
1995
β-Adrenergic Modulation of the Collateral-Dependent Coronary Microcirculation
Sellke F, Wang S, Friedman M, Bin Dai H, Harada K, Lopez J, Simons M. β-Adrenergic Modulation of the Collateral-Dependent Coronary Microcirculation. Journal Of Surgical Research 1995, 59: 185-190. PMID: 7630126, DOI: 10.1006/jsre.1995.1152.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorCollateral-dependent LCx regionLCx regionCoronary microcirculationBlood flowProximal left circumflex coronary arteryLeft circumflex coronary arteryCollateral-dependent areaCollateral-dependent perfusionCoronary arterial microvesselsCoronary microvascular responsesLCX blood flowProximal (<b>d</b>) LCX arteryCircumflex coronary arteryCollateral-dependent myocardiumRapid atrial pacingEndothelial growth factorΒ-Adrenergic ModulationAdenylate cyclase activator forskolinRelaxations of microvesselsCyclase activator forskolinChronic treatmentLeft anteriorMicrovascular relaxationAtrial pacing