2022
Delayed Mortality Among Solid Organ Transplant Recipients Hospitalized for COVID-19
Heldman MR, Kates OS, Safa K, Kotton CN, Multani A, Georgia SJ, Steinbrink JM, Alexander BD, Blumberg EA, Haydel B, Hemmige V, Hemmersbach-Miller M, La Hoz RM, Moni L, Condor Y, Flores S, Munoz CG, Guitierrez J, Diaz EI, Diaz D, Vianna R, Guerra G, Loebe M, Yabu JM, Kramer KH, Tanna SD, Ison MG, Rakita RM, Malinis M, Azar MM, McCort ME, Singh PP, Velioglu A, Mehta SA, van Duin D, Goldman JD, Lease ED, Wald A, Limaye AP, Fisher CE, Besharatian B, Crespo M, Tomic R, Sehgal S, Weisshaar D, Girgis R, Lawrence C, Nelson J, Bennett W, Leandro J, Sait A, Rumore A, West P, Jeng A, Bajrovic V, Bilgili E, Anderson-Haag T, Nastase A, Badami A, Alvarez-Garcia J, Bowman-Anger L, Julien L, Ortiz-Bautista C, Friedman-Morocco R, Gajurel K, Cahuayme-Zuniga L, Wakefield M, Fung M, Theodoropoulos N, Chuang S, Bhandaram S, Veroux M, Chopra B, Florescu D, Witteck D, Diaz D, Ripley K, Saharia K, Akkina S, McCarty T, Webb A, Arya A, Vedula G, El-Amm J, Dokus M, Narayanan A, de Camargo P, Ouseph R, Breuckner A, Luk A, Aujayeb A, Ganger D, Keith D, Meloni F, Haidar G, Zapernick L, Morales M, Goyal N, Sharma T, Malhotra U, Kuo A, Rossi A, Edwards A, Keller B, Beneri C, Derringer D, Dominguez E, Carlson E, Hashim F, Murad H, Wilkens H, Neumann H, Gani I, Kahwaji J, Popoola J, Michaels M, Jakharia N, De la Cruz O, Puing A, Motallebzadeh R, Velagapudi R, Kapoor R, Allam S, Silveira F, Vora S, Kelly U, Reddy U, Dharnidharka V, Wadei H, Zurabi L. Delayed Mortality Among Solid Organ Transplant Recipients Hospitalized for COVID-19. Clinical Infectious Diseases 2022, 78: 711-718. PMID: 35212363, PMCID: PMC9383518, DOI: 10.1093/cid/ciac159.Peer-Reviewed Original ResearchSOT recipientsDay 28Day 90Multivariable Cox proportional hazards modelsSolid organ transplant recipientsCOVID-19Cox proportional hazards modelCOVID-19 focusOrgan transplant recipientsChronic lung diseaseBody mass indexProportional hazards modelSARS-CoV-2 detectionLung transplantMulticenter registryTransplant recipientsHeart failureMass indexIllness onsetVital statusLung diseaseRisk factorsDay 29Lower mortalityMortality
2021
A retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients
Ringer M, Azmy V, Kaman K, Tang D, Cheung H, Azar MM, Price C, Malinis M. A retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients. Transplant Infectious Disease 2021, 23: e13556. PMID: 33378571, PMCID: PMC7883059, DOI: 10.1111/tid.13556.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedCase-Control StudiesCohort StudiesComorbidityCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeFemaleGlucocorticoidsGraft RejectionHeart TransplantationHospitalizationHumansImmunologic FactorsImmunosuppressive AgentsInterleukin-10Interleukin-6Kidney TransplantationLiver TransplantationMaleMiddle AgedReceptors, Interleukin-2Retrospective StudiesSARS-CoV-2Severity of Illness IndexTreatment OutcomeYoung AdultConceptsCytokine release syndromeBody mass indexNon-SOT patientsSOT groupSOT patientsRelease syndromeInterleukin-6COVID-19-related cytokine release syndromeSoluble interleukin-2 receptor levelsControl groupInterleukin-2 receptor levelsSolid organ transplant patientsSolid organ transplant recipientsImpact of immunomodulationInterleukin-10 levelsOrgan transplant recipientsOrgan transplant patientsCritical care needsMulti-center studyCoronavirus disease 2019COVID-19Interleukin levelsIndex hospitalizationTransplant patientsTransplant recipients