2014
Electron Microscopy Contribution to Diagnosing Transplant Glomerulopathy: A Single-Center Experience
Rigo D, Barrón MB, Martinatto C, Mukdsi J, Orías M, Novoa P. Electron Microscopy Contribution to Diagnosing Transplant Glomerulopathy: A Single-Center Experience. Transplantation Proceedings 2014, 46: 2975-2980. PMID: 25420804, DOI: 10.1016/j.transproceed.2014.07.008.Peer-Reviewed Original ResearchConceptsInterstitial fibrosis/tubular atrophyDeceased donor renal transplantLower graft survivalPercent of patientsKidney transplant biopsiesSingle-center experienceIdentification of patientsGraft dysfunctionGraft survivalRenal transplantTransplant biopsiesTransplant glomerulopathyGraft pathologyTubular atrophyStudy criteriaHistologic changesPatientsAverage evolution timeEarly changesAccurate diagnosisLight microscopyTransplantation timeBiopsyDiagnosisTransplantation
2013
Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertension
Romero CA, Alfie J, Galarza C, Waisman G, Peixoto AJ, Tabares AH, Orias M. Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertension. International Journal Of Cardiology Cardiovascular Risk And Prevention 2013, 7: 157-162. PMID: 23403215, DOI: 10.1016/j.jash.2013.01.001.Peer-Reviewed Original ResearchConceptsSystemic vascular resistanceStroke volume indexDiastolic hypertensionCardiac indexHemodynamic patternsHeart rateTotal arterial compliance indexAmbulatory blood pressure monitoringHigher systemic vascular resistanceNormal systemic vascular resistanceArterial compliance indexLow cardiac indexHigher cardiac indexBlood pressure monitoringSVR groupVascular resistanceYounger patientsBlood pressureHypertensive individualsHypertension patientsPathophysiologic mechanismsMean agePulse pressureHypertensionPressure monitoring
2011
Preemptive Kidney Transplantation: Experience in Two Centers
Rigo DH, Ziraldo L, Di Monte L, Jimenez MP, Giotto AP, Gutierrez L, Rodriguez I, Orias M, Novoa PA. Preemptive Kidney Transplantation: Experience in Two Centers. Transplantation Proceedings 2011, 43: 3355-3358. PMID: 22099795, DOI: 10.1016/j.transproceed.2011.09.083.Peer-Reviewed Original ResearchConceptsPreemptive kidney transplantEnd-stage renal diseaseDelayed graft functionSubclinical rejectionKidney transplantDeceased donorsInterstitial fibrosis/tubular atrophyDeceased donor groupChronic allograft nephropathyPreemptive kidney transplantationRenal replacement therapyDonor kidney transplantsLong-term dialysisQuality of lifeAllograft nephropathyGraft functionKidney transplantationPreemptive transplantationMonths posttransplantationSerum creatinineTransplantation centersRenal diseaseTubular atrophyCalcineurin inhibitorsPoor outcome
2010
Hypothesis: It Is Time to Reconsider Phenotypes in Hypertension
Orias M, Tabares AH, Peixoto AJ. Hypothesis: It Is Time to Reconsider Phenotypes in Hypertension. Journal Of Clinical Hypertension 2010, 12: 350-356. PMID: 20546376, PMCID: PMC8673086, DOI: 10.1111/j.1751-7176.2010.00266.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2007
Association of ACE genotype and predominantly diastolic hypertension: a preliminary study
Jiménez PM, Conde C, Casanegra A, Romero C, Hugo Tabares A, Orías M. Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. Journal Of The Renin-Angiotensin-Aldosterone System 2007, 8: 42-44. PMID: 17487825, DOI: 10.3317/jraas.2007.006.Peer-Reviewed Original ResearchConceptsPDH patientsDiastolic hypertensionBlood pressureGenotype distributionACE I/D polymorphismAngiotensin-converting enzyme polymorphismACE genotype DDAngiotensin II activityNormotensive control individualsCardiovascular risk factorsHigher plasma ACE levelsSystolic blood pressurePlasma ACE levelsChi-square testMmHg systolicEssential hypertensionPeripheral resistanceNormotensive controlsACE genotypeACE levelsRisk factorsDD genotypeD polymorphismHypertensionPatients
2000
Reproducibility of ambulatory blood pressure monitoring in hemodialysis patients
Peixoto A, Santos S, Mendes R, Crowley S, Maldonado R, Orias M, Mansoor G, White W. Reproducibility of ambulatory blood pressure monitoring in hemodialysis patients. American Journal Of Kidney Diseases 2000, 36: 983-990. PMID: 11054355, DOI: 10.1053/ajkd.2000.19100.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure monitoringInterdialytic ambulatory blood pressure monitoringBlood pressure monitoringPost-HD valuesHD patientsPressure monitoringReproducibility of ABPMDrug regimenHemodialysis patientsHemodialysis practiceHD sessionNocturnal declineInterdialytic periodPatientsBP determinationRegimenPeriodSleepCoefficient of variationKCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels
Lang R, Lee G, Liu W, Tian S, Rafi H, Orias M, Segal A, Desir G. KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels. American Journal Of Physiology. Renal Physiology 2000, 278: f1013-f1021. PMID: 10836990, DOI: 10.1152/ajprenal.2000.278.6.f1013.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCyclic Nucleotide-Gated Cation ChannelsDNA PrimersFemaleHumansIn Vitro TechniquesIon Channel GatingIon ChannelsMembrane PotentialsOocytesPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsPotassium Channels, Voltage-GatedRabbitsRecombinant ProteinsSecond Messenger SystemsShaker Superfamily of Potassium ChannelsXenopus laevis