2024
Lung function and health-related quality of life among adult patients following pulmonary TB treatment.
Zawedde J, Abelman R, Musisi E, Nyabigambo A, Sanyu I, Kaswabuli S, Byanyima P, Lewis E, Sessolo A, Lalitha R, Kiwanuka N, Crothers K, Worodria W, Davis J, Huang L. Lung function and health-related quality of life among adult patients following pulmonary TB treatment. The International Journal Of Tuberculosis And Lung Disease 2024, 28: 419-426. PMID: 39187999, DOI: 10.5588/ijtld.24.0029.Peer-Reviewed Original ResearchConceptsSt. George's Respiratory QuestionnaireQuality of lifeAbnormal lung functionSpirometric restrictionHealth-related quality of lifeLung functionPost-TB lung diseaseHealth-related qualityFemale sexRisk factorsFunctional abnormalitiesGeorge's Respiratory QuestionnairePTB treatmentPulmonary TB treatmentAssociated with increased morbidityChronic lung complicationsPrevalence ratiosResource-limited settingsChest X-rayLung function abnormalitiesRespiratory QuestionnaireSGRQ scoreAssociated with lung function abnormalitiesSmoking statusBilateral consolidation
2022
Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia
Saranjav A, Parisi C, Zhou X, Dorjnamjil K, Samdan T, Erdenebaatar S, Chuluun A, Dalkh T, Ganbaatar G, Brooks MB, Spiegelman D, Ganmaa D, Davis JL. Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia. BMJ Open 2022, 12: e061229. PMID: 35973702, PMCID: PMC9386240, DOI: 10.1136/bmjopen-2022-061229.Peer-Reviewed Original ResearchMeSH KeywordsContact TracingCross-Sectional StudiesHumansMaleMongoliaRetrospective StudiesTuberculosisTuberculosis, PulmonaryConceptsPrimary health centersTB preventive therapyRoutine surveillance dataHealth centersHousehold contactsCohort studyPreventive therapyTB careTB dispensariesRetrospective cross-sectional cohort studyCross-sectional cohort studySurveillance dataActive TB treatmentGuideline-adherent careHealth system predictorsQuality of tuberculosisOdds of patientsHealth system factorsQuality improvement interventionsLow-quality careCare cascadeTB screeningTB treatmentTuberculosis careIndex patients
2021
Evaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study.
Diaz G, Victoria AM, Meyer AJ, Niño Y, Luna L, Ferro BE, Davis J. Evaluating the Quality of Tuberculosis Contact Investigation in Cali, Colombia: A Retrospective Cohort Study. American Journal Of Tropical Medicine And Hygiene 2021, 104: 1309-1316. PMID: 33617470, PMCID: PMC8045602, DOI: 10.4269/ajtmh.20-0809.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultColombiaContact TracingFamily CharacteristicsFemaleHumansMaleMiddle AgedOdds RatioRetrospective StudiesTuberculosisTuberculosis, PulmonaryYoung AdultConceptsRetrospective cohort studyTuberculosis contact investigationContact investigationTB patientsHousehold visitsTB evaluationClinic visitsCohort studyEarly TB diagnosisIndex TB patientsTB contact investigationActive TB patientsTherapy initiationPreventive therapyTB diagnosisSymptomatic contactsMultivariable modelClinic referralsIndex patientsPatientsContact tracingVisitsCumulative probabilityLittle dataReferral
2018
The impact of digital health technologies on tuberculosis treatment: a systematic review
Ngwatu B, Nsengiyumva N, Oxlade O, Mappin-Kasirer B, Nguyen N, Jaramillo E, Falzon D, Schwartzman K, Abubakar I, Alipanah N, Bastos M, Boccia D, Chin D, Cohen T, Davis J, Denkinger C, Falzon D, Fielding K, Fox G, Free C, Garfein R, Hayward A, Jaramillo E, Lester R, Lewis J, Mappin-Kasirer B, Marx F, Menzies D, Migliori G, Nahid P, Ngwatu B, Nsengiyumva N, Nguyen N, Oxlade O, Schwartzman K, Siddiqi K, Story A, Thomas B, Trajman A, Yassin M. The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal 2018, 51: 1701596. PMID: 29326332, PMCID: PMC5764088, DOI: 10.1183/13993003.01596-2017.Peer-Reviewed Original ResearchConceptsVideo-observed therapyMedication monitorsStandard careObservational studyTreatment completion ratesTB treatment adherenceProbability of cureTreatment of personsPerson DOTActive tuberculosisTB careClinical outcomesTreatment adherenceTuberculosis treatmentPatient outcomesTreatment completionControl groupTreatment dosesSystematic reviewDigital health technologiesShort message serviceEffect estimatesTuberculosisDigital interventionsCare
2017
Bringing patient-centered tuberculosis diagnosis into the light of day
Davis JL. Bringing patient-centered tuberculosis diagnosis into the light of day. BMC Medicine 2017, 15: 219. PMID: 29258526, PMCID: PMC5738029, DOI: 10.1186/s12916-017-0992-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultCosts and Cost AnalysisDiagnostic Tests, RoutineHumansIncidenceMicroscopyPatient-Centered CareSputumTuberculosisTuberculosis, PulmonaryConceptsSmear microscopySame-day sputum smear microscopyTB diagnostic toolsPatient-centered TB careEnd TB Strategy goalsPatient-centered careSputum smear microscopyPatient-centered servicesTuberculosis deathsTB careTB StrategyTuberculosis diagnosisDiagnostic careCatastrophic costsRecent evidenceCareDiagnostic toolRelated articles
2015
Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis
Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL. Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis. The Journal Of Infectious Diseases 2015, 212: 990-998. PMID: 25762787, PMCID: PMC4548467, DOI: 10.1093/infdis/jiv149.Peer-Reviewed Original ResearchConceptsDrug-tolerant bacilliDrug exposureDrug-susceptible pulmonary tuberculosisDrug-tolerant Mycobacterium tuberculosisDrug-susceptible Mycobacterium tuberculosisMycobacterium tuberculosisTuberculosis treatment regimensInitial drug exposureReverse transcription-polymerase chain reactionMessenger RNA expressionM. tuberculosis gene expressionDrug efflux pumpsSerial sputaPulmonary tuberculosisTreatment initiationNovel drug targetsTreatment regimensPolymerase chain reactionToxin-antitoxin genesHuman tuberculosisRate of declineDrug responsivenessStress signatureMarked downregulationDrug tolerance