2024
Impact of a multicomponent strategy including decentralized molecular testing for tuberculosis on mortality: planned analysis of a cluster-randomized trial in Uganda
Katamba A, Mochizuki T, Nalugwa T, Nantale M, Oyuku D, Nabwire S, Babirye D, Musinguzi J, Nakawesa A, Nekesa I, Turyahabwe S, Joloba M, Dowdy D, Moore D, Davis J, Shete P, Adams K, Reza T, Fielding K, Cattamanchi A. Impact of a multicomponent strategy including decentralized molecular testing for tuberculosis on mortality: planned analysis of a cluster-randomized trial in Uganda. EClinicalMedicine 2024, 78: 102953. PMCID: PMC11629260, DOI: 10.1016/j.eclinm.2024.102953.Peer-Reviewed Original ResearchCommunity health centersCluster randomized trialHealth centersPragmatic cluster randomized trialMulticomponent strategiesSix-month mortality riskSecondary outcomesPan African Clinical Trials RegistryCluster-level analysisPatient-level covariatesAll-cause mortalityClinical Trials RegistryIntervention armSub-group analysisTB careMortality risk analysisRoutine careVital statusTrial armsMagnitude of effectPresumptive TBRate ratiosProximal outcomesTrial participantsUS National Institutes
2022
Is aggregated surveillance data a reliable method for constructing tuberculosis care cascades? A secondary data analysis from Uganda
White E, Hernández-Ramírez R, Majwala R, Nalugwa T, Reza T, Cattamanchi A, Katamba A, Davis J. Is aggregated surveillance data a reliable method for constructing tuberculosis care cascades? A secondary data analysis from Uganda. PLOS Global Public Health 2022, 2: e0000716. PMID: 36962541, PMCID: PMC10045605, DOI: 10.1371/journal.pgph.0000716.Peer-Reviewed Original ResearchNational TB ProgrammeTreatment initiationAntiretroviral therapySurveillance dataLimits of agreementFacility characteristicsTB surveillance dataTuberculosis care cascadeNumber of peopleXpert-positivesCare cascadeTB careTB treatmentTB programsTuberculosis controlQuality improvement toolsSecondary data analysisHealth facilitiesPositive diagnosisAddress reasonsLinear mixed modelsConcordance correlation coefficientHIVTherapyDiagnosisAssessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia
Saranjav A, Parisi C, Zhou X, Dorjnamjil K, Samdan T, Erdenebaatar S, Chuluun A, Dalkh T, Ganbaatar G, Brooks MB, Spiegelman D, Ganmaa D, Davis JL. Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia. BMJ Open 2022, 12: e061229. PMID: 35973702, PMCID: PMC9386240, DOI: 10.1136/bmjopen-2022-061229.Peer-Reviewed Original ResearchConceptsPrimary health centersTB preventive therapyRoutine surveillance dataHealth centersHousehold contactsCohort studyPreventive therapyTB careTB dispensariesRetrospective cross-sectional cohort studyCross-sectional cohort studySurveillance dataActive TB treatmentGuideline-adherent careHealth system predictorsQuality of tuberculosisOdds of patientsHealth system factorsQuality improvement interventionsLow-quality careCare cascadeTB screeningTB treatmentTuberculosis careIndex patients
2018
The impact of digital health technologies on tuberculosis treatment: a systematic review
Ngwatu B, Nsengiyumva N, Oxlade O, Mappin-Kasirer B, Nguyen N, Jaramillo E, Falzon D, Schwartzman K, Abubakar I, Alipanah N, Bastos M, Boccia D, Chin D, Cohen T, Davis J, Denkinger C, Falzon D, Fielding K, Fox G, Free C, Garfein R, Hayward A, Jaramillo E, Lester R, Lewis J, Mappin-Kasirer B, Marx F, Menzies D, Migliori G, Nahid P, Ngwatu B, Nsengiyumva N, Nguyen N, Oxlade O, Schwartzman K, Siddiqi K, Story A, Thomas B, Trajman A, Yassin M. The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal 2018, 51: 1701596. PMID: 29326332, PMCID: PMC5764088, DOI: 10.1183/13993003.01596-2017.Peer-Reviewed Original ResearchConceptsVideo-observed therapyMedication monitorsStandard careObservational studyTreatment completion ratesTB treatment adherenceProbability of cureTreatment of personsPerson DOTActive tuberculosisTB careClinical outcomesTreatment adherenceTuberculosis treatmentPatient outcomesTreatment completionControl groupTreatment dosesSystematic reviewDigital health technologiesShort message serviceEffect estimatesTuberculosisDigital interventionsCare
2017
Bringing patient-centered tuberculosis diagnosis into the light of day
Davis JL. Bringing patient-centered tuberculosis diagnosis into the light of day. BMC Medicine 2017, 15: 219. PMID: 29258526, PMCID: PMC5738029, DOI: 10.1186/s12916-017-0992-4.Peer-Reviewed Original ResearchConceptsSmear microscopySame-day sputum smear microscopyTB diagnostic toolsPatient-centered TB careEnd TB Strategy goalsPatient-centered careSputum smear microscopyPatient-centered servicesTuberculosis deathsTB careTB StrategyTuberculosis diagnosisDiagnostic careCatastrophic costsRecent evidenceCareDiagnostic toolRelated articles