2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfection
2014
One size does not fit all: why universal decolonization strategies to prevent methicillin-resistant Staphylococcus aureus colonization and infection in adult intensive care units may be inappropriate for neonatal intensive care units
Nelson MU, Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. One size does not fit all: why universal decolonization strategies to prevent methicillin-resistant Staphylococcus aureus colonization and infection in adult intensive care units may be inappropriate for neonatal intensive care units. Journal Of Perinatology 2014, 34: 653-655. PMID: 25010223, PMCID: PMC4152419, DOI: 10.1038/jp.2014.125.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitAdult intensive care unitsCare unitUniversal decolonizationMethicillin-resistant Staphylococcus aureus (MRSA) colonizationMRSA-positive clinical cultureUnique patient populationLarge multicenter trialsStaphylococcus aureus colonizationLong-term safetyMupirocin applicationAdverse eventsPreterm infantsLarge multicenterMulticenter trialPatient populationAureus colonizationDecolonization strategiesClinical culturesDisease controlHealthcare ResearchTrialsTrial methodsWidespread implementation
2013
Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial
Harris AD, Pineles L, Belton B, Johnson JK, Shardell M, Loeb M, Newhouse R, Dembry L, Braun B, Perencevich EN, Hall KK, Morgan DJ, Shahryar S, Price C, Gadbaw J, Drees M, Kett D, Muñoz-Price L, Jacob J, Herwaldt L, Sulis C, Yokoe D, Maragakis L, Lissauer M, Zervos M, Warren D, Carver R, Anderson D, Calfee D, Bowling J, Safdar N. Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial. JAMA 2013, 310: 1571-1580. PMID: 24097234, PMCID: PMC4026208, DOI: 10.1001/jama.2013.277815.Peer-Reviewed Original ResearchMeSH KeywordsAgedCross InfectionEnterococcusFemaleGloves, ProtectiveGram-Positive Bacterial InfectionsGuideline AdherenceHand DisinfectionHumansInfection ControlIntensive Care UnitsMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPersonnel, HospitalStaphylococcal InfectionsSurgical AttireVancomycin ResistanceConceptsIntensive care unitMethicillin-resistant Staphylococcus aureusVancomycin-resistant EnterococcusIntervention ICUsSurgical intensive care unitPrimary outcomeHand hygiene complianceSecondary outcomesAdverse eventsPatient contactUniversal gloveVRE acquisitionUsual careMRSA acquisitionGown useHygiene complianceAcquisition of MRSAAntibiotic-resistant bacteriaControl intensive care unitHealth care-associated infectionsStudy periodKey secondary outcomesBaseline periodCare-associated infectionsHealth care workers
2007
Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections
Gupta K, MacIntyre A, Vanasse G, Dembry LM. Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections. Journal Of Clinical Microbiology 2007, 45: 3930-3934. PMID: 17942648, PMCID: PMC2168566, DOI: 10.1128/jcm.01510-07.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBeta-LactamsChildChild, PreschoolCommunity-Acquired InfectionsDrug PrescriptionsFemaleHealth Services ResearchHumansInfantInfant, NewbornMaleMethicillin ResistanceMiddle AgedPrevalenceStaphylococcal InfectionsStaphylococcus aureusUnited StatesConceptsCA-MRSA soft tissue infectionsSoft tissue infectionsInitial empirical therapyCA-MRSA isolatesEmpirical therapyAntimicrobial therapyCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolatesStaphylococcal chromosomal cassette mec type IVS. aureus soft tissue infectionsResistant Staphylococcus aureus infectionsMethicillin-Resistant Staphylococcus aureus IsolatesInactive antimicrobial therapyRate of prescribingCA-MRSA infectionsInitial antimicrobial therapyMajority of patientsMedical record reviewSubset of patientsCommunity-Associated MethicillinStaphylococcus aureus infectionPanton-Valentine leukocidinStaphylococcus aureus isolatesBeta-lactam antibioticsDiscordant therapyRate of use
1997
RENAL AND PERIRENAL ABSCESSES
Dembry LM, Andriole VT. RENAL AND PERIRENAL ABSCESSES. Infectious Disease Clinics Of North America 1997, 11: 663-680. PMID: 9378929, DOI: 10.1016/s0891-5520(05)70379-2.Peer-Reviewed Original ResearchConceptsRenal cortical abscessCortical abscessesIntrarenal abscessAntibiotic therapyAcute multifocal bacterial nephritisAcute focal bacterial nephritisFocal bacterial nephritisRenal corticomedullaryPerirenal abscessRenal abscessSerious prognosisXanthogranulomatous pyelonephritisClinical presentationElusive diagnosisNegative uropathogensAntistaphylococcal therapyComplete nephrectomyAbscessRadiographic studiesRadiologic techniquesTherapyNephritisDiagnosisPyelonephritisNephrectomy