2017
Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching
Kaltenbach TR, Soetikno RM, DeVivo R, Laine LA, Barkun A, McQuaid KR, Group O, Cheifetz A, Chiorean M, East J, Farraye F, Leighton J, Levesque B, Lichtenstein G, Marion J, Matsumoto T, Mönkemüller K, Picco M, Odze R, Raju G, Rutter M, Rex D, Shen B, Shergill A, Subramanian V. Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching. Gastrointestinal Endoscopy 2017, 86: 1107-1117.e1. PMID: 28818507, DOI: 10.1016/j.gie.2017.07.045.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseManagement of dysplasiaUse of chromoendoscopyVisible dysplastic lesionsIBD surveillanceQuiescent diseaseBowel diseaseDysplastic lesionsDysplasia detectionColonic inflammatory bowel diseaseColorectal Endoscopic Neoplasia DetectionInflammatory bowel disease patientsBowel disease patientsUptake of strategiesQuality of endoscopyInternational consensus recommendationsEvidence-based advancesAcademic medical centerDetection of dysplasiaImage-enhanced endoscopyUse of EMRDysplasia managementIBD courseColorectal dysplasiaDisease activity
2016
Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis
Park S, Abdi T, Gentry M, Laine L. Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis. The American Journal Of Gastroenterology 2016, 111: 1692. PMID: 27725645, DOI: 10.1038/ajg.2016.418.Peer-Reviewed Original ResearchConceptsRelapse/exacerbationHistological remissionEndoscopic remissionClinical remissionHistological activityClinical outcomesUlcerative colitisHistological statusClinical relapseHistological featuresLamina propriaChronic inflammatory cell infiltrateAdditional prognostic utilityHistological disease activityProportion of patientsInflammatory bowel diseaseInflammatory cell infiltrateLack of blindingImproved clinical outcomesDifferent histological featuresSpecific histological featuresRandom-effects modelFixed-effects modelDisease activityUC patients
2015
Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men
Clark BT, Protiva P, Nagar A, Imaeda A, Ciarleglio MM, Deng Y, Laine L. Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men. Gastroenterology 2015, 150: 396-405. PMID: 26439436, PMCID: PMC4728019, DOI: 10.1053/j.gastro.2015.09.041.Peer-Reviewed Original ResearchConceptsAdequate bowel preparationBBPS scoreSurveillance colonoscopyBowel preparationColon segmentsBBPS scoresSecond examinationWest Haven Veterans Affairs Medical CenterVeterans Affairs Medical CenterFirst examinationGuideline-recommended intervalsProspective observational studyDetection of adenomasIdentification of polypsColonoscopic evaluationPrimary outcomeSurveillance intervalsBlinded endoscopistsColonoscopy examinationObservational studyPrEP scaleMedical CenterInitial examinationStudy subjectsAdequate preparation