2021
Towards personalised management for non-variceal upper gastrointestinal bleeding
Sung JJY, Laine L, Kuipers EJ, Barkun AN. Towards personalised management for non-variceal upper gastrointestinal bleeding. Gut 2021, 70: 818-824. PMID: 33649044, DOI: 10.1136/gutjnl-2020-323846.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsEndoscopy, GastrointestinalGastrointestinal HemorrhageHemostasis, EndoscopicHumansPractice Guidelines as TopicPrecision MedicineUpper Gastrointestinal TractConceptsIndividual patientsNon-variceal upper gastrointestinal bleedingPre-endoscopic assessmentUpper gastrointestinal bleedingImportant clinical issuePostendoscopic managementGastrointestinal bleedingPatient characteristicsEndoscopic evaluationPoint of careOptimal treatmentInternational guidelinesClinical issuesInternational professional societiesClinical settingSpecific management strategiesStages of managementPatientsTreatmentProfessional societiesManagement strategiesGuidelinesBleedingHaemostasisLesions
2020
Monitoring Fecal Microbiota Transplantation Practice in a Rapidly Evolving Health and Regulatory Environment
Kelly CR, Laine LA, Wu GD. Monitoring Fecal Microbiota Transplantation Practice in a Rapidly Evolving Health and Regulatory Environment. Gastroenterology 2020, 159: 2004-2006. PMID: 32841646, PMCID: PMC7443160, DOI: 10.1053/j.gastro.2020.08.039.Commentaries, Editorials and Letters
2019
Management of acute upper gastrointestinal bleeding
Stanley AJ, Laine L. Management of acute upper gastrointestinal bleeding. The BMJ 2019, 364: l536. PMID: 30910853, DOI: 10.1136/bmj.l536.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnti-Bacterial AgentsBlood TransfusionDisease ManagementEndoscopy, GastrointestinalEsophageal and Gastric VaricesGastrointestinal HemorrhageHumansLiver CirrhosisPortasystemic Shunt, Transjugular IntrahepaticPractice Guidelines as TopicProton Pump InhibitorsResuscitationSeverity of Illness IndexConceptsUpper gastrointestinal bleedingProton pump inhibitorsVariceal bleedingUlcer bleedingGastrointestinal bleedingEndoscopic therapyVasoactive drugsPump inhibitorsHigh-dose proton pump inhibitorsAcute upper gastrointestinal bleedingDose proton pump inhibitorsTransjugular intrahepatic portosystemic shuntNon-variceal bleedingRecurrent ulcer bleedingRecurrent variceal bleedingRed cell transfusionCommon medical emergencyIntrahepatic portosystemic shuntEarly endoscopyCell transfusionHemodynamic instabilityHemoglobin thresholdEndoscopic treatmentIntravenous fluidsPortosystemic shunt
2017
Transparency ethics in practice: Revisiting financial conflicts of interest disclosure forms in clinical practice guidelines
Lu Y, Jones DJ, Sharara N, Kaltenbach T, Laine L, McQuaid K, Soetikno R, Subramanian V, Barkun A. Transparency ethics in practice: Revisiting financial conflicts of interest disclosure forms in clinical practice guidelines. PLOS ONE 2017, 12: e0182856. PMID: 28841650, PMCID: PMC5571907, DOI: 10.1371/journal.pone.0182856.Peer-Reviewed Original ResearchOptimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching
Kaltenbach TR, Soetikno RM, DeVivo R, Laine LA, Barkun A, McQuaid KR, Group O, Cheifetz A, Chiorean M, East J, Farraye F, Leighton J, Levesque B, Lichtenstein G, Marion J, Matsumoto T, Mönkemüller K, Picco M, Odze R, Raju G, Rutter M, Rex D, Shen B, Shergill A, Subramanian V. Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching. Gastrointestinal Endoscopy 2017, 86: 1107-1117.e1. PMID: 28818507, DOI: 10.1016/j.gie.2017.07.045.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseManagement of dysplasiaUse of chromoendoscopyVisible dysplastic lesionsIBD surveillanceQuiescent diseaseBowel diseaseDysplastic lesionsDysplasia detectionColonic inflammatory bowel diseaseColorectal Endoscopic Neoplasia DetectionInflammatory bowel disease patientsBowel disease patientsUptake of strategiesQuality of endoscopyInternational consensus recommendationsEvidence-based advancesAcademic medical centerDetection of dysplasiaImage-enhanced endoscopyUse of EMRDysplasia managementIBD courseColorectal dysplasiaDisease activity
2016
Upper Gastrointestinal Bleeding Due to a Peptic Ulcer
Laine L. Upper Gastrointestinal Bleeding Due to a Peptic Ulcer. New England Journal Of Medicine 2016, 374: 2367-2376. PMID: 27305194, DOI: 10.1056/nejmcp1514257.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsParadigm Shift in the Surveillance and Management of Dysplasia in Inflammatory Bowel Disease (West)
Soetikno R, Kaltenbach T, McQuaid KR, Subramanian V, Kumar R, Barkun AN, Laine L. Paradigm Shift in the Surveillance and Management of Dysplasia in Inflammatory Bowel Disease (West). Digestive Endoscopy 2016, 28: 266-273. PMID: 26866420, DOI: 10.1111/den.12634.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsColonoscopyColorectal NeoplasmsEarly Detection of CancerHumansInflammatory Bowel DiseasesPopulation SurveillancePractice Guidelines as TopicConceptsManagement of dysplasiaColorectal cancerUlcerative colitisInflammatory bowel disease colitisCrohn's disease (CD) colitisInflammatory bowel diseaseEarly colorectal cancerDysplasia associated lesionHigh-definition colonoscopyInstitute of MedicineNew surveillance paradigmMost dysplasiaColorectal dysplasiaResectable lesionsSurveillance colonoscopyBowel diseaseGRADE methodologyAssociated lesionsTargeted biopsiesConsensus statementHigh riskGeneral populationEndoscopic recognitionGuideline developmentDysplasia
2015
A roadmap to the implementation of chromoendoscopy in inflammatory bowel disease colonoscopy surveillance practice
Sanduleanu S, Kaltenbach T, Barkun A, McCabe RP, Velayos F, Picco MF, Laine L, Soetikno R, McQuaid KR. A roadmap to the implementation of chromoendoscopy in inflammatory bowel disease colonoscopy surveillance practice. Gastrointestinal Endoscopy 2015, 83: 213-222. PMID: 26364967, DOI: 10.1016/j.gie.2015.08.076.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsColitis, UlcerativeColonoscopyColorectal NeoplasmsColoring AgentsDisease ManagementEarly Detection of CancerHumansInflammatory Bowel DiseasesPractice Guidelines as Topic
2009
Prescription rates of protective co‐therapy for NSAID users at high GI risk and results of attempts to improve adherence to guidelines
LAINE L, CONNORS L, GRIFFIN MR, CURTIS SP, KAUR A, CANNON CP. Prescription rates of protective co‐therapy for NSAID users at high GI risk and results of attempts to improve adherence to guidelines. Alimentary Pharmacology & Therapeutics 2009, 30: 767-774. PMID: 19594486, DOI: 10.1111/j.1365-2036.2009.04090.x.Peer-Reviewed Original ResearchAdherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary‐care providers
SPIEGEL BM, FARID M, VAN OIJEN MG, LAINE L, HOWDEN CW, ESRAILIAN E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary‐care providers. Alimentary Pharmacology & Therapeutics 2009, 29: 871-881. PMID: 19183152, PMCID: PMC2953468, DOI: 10.1111/j.1365-2036.2009.03935.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunity Health ServicesDyspepsiaFemaleGastroenterologyGuideline AdherenceHumansMaleMiddle AgedNurse PractitionersPhysicians, FamilyPractice Guidelines as TopicSurveys and QuestionnairesConceptsPrimary care providersProton pump inhibitorsCommunity gastroenterologistsFirst-line proton pump inhibitorsLong-term PPI useLower guideline adherencePPI useAdverse eventsGuideline adherenceDyspepsia managementPump inhibitorsPCP groupPractice guidelinesTherapeutic decisionsBest practice guidelinesDyspepsiaGastroenterologistsConfirmatory testingAdherenceVignette surveyGuidelinesMore concernBest practicesProvidersGroup
2007
Is an evidence-based approach to creating guidelines always the right one?
Fried M, Quigley E, Hunt R, Guyatt G, Anderson B, Bjorkman D, Farthing M, Fedail S, Green-Thompson R, Hampton J, Krabshuis J, Laine L, Horton R. Is an evidence-based approach to creating guidelines always the right one? Nature Reviews Gastroenterology & Hepatology 2007, 5: 60-61. PMID: 17998924, DOI: 10.1038/ncpgasthep0997.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAre global guidelines desirable, feasible and necessary?
Fried M, Quigley E, Hunt R, Guyatt G, Anderson B, Bjorkman D, Farthing M, Fedail S, Green-Thompson R, Hampton J, Krabshuis J, Laine L, Horton R. Are global guidelines desirable, feasible and necessary? Nature Reviews Gastroenterology & Hepatology 2007, 5: 2-3. PMID: 17998926, DOI: 10.1038/ncpgasthep0994.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2004
Guidelines for the appropriate use of non‐steroidal anti‐inflammatory drugs, cyclo‐oxygenase‐2‐specific inhibitors and proton pump inhibitors in patients requiring chronic anti‐inflammatory therapy
Dubois RW, Melmed GY, Henning JM, Laine L. Guidelines for the appropriate use of non‐steroidal anti‐inflammatory drugs, cyclo‐oxygenase‐2‐specific inhibitors and proton pump inhibitors in patients requiring chronic anti‐inflammatory therapy. Alimentary Pharmacology & Therapeutics 2004, 19: 197-208. PMID: 14723611, DOI: 10.1111/j.0269-2813.2004.01834.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProton pump inhibitorsCost of NSAIDsPump inhibitorsGastrointestinal eventsChronic anti-inflammatory therapyRAND/UCLA Appropriateness MethodNon-steroidal anti-inflammatory drugsAnti-inflammatory therapyAnti-inflammatory drugsDrug treatment strategiesCommunity-based settingsCardiovascular riskProphylactic useAppropriateness MethodTreatment strategiesLower riskNSAIDsPatientsClinical scenariosAspirinAppropriate useInhibitorsRiskCare entitiesLiterature review
1999
Review article: nonsteroidal anti‐inflammatory drug‐associated gastrointestinal complications—guidelines for prevention and treatment
Schoenfeld, Kimmey, Scheiman, Bjorkman, Laine. Review article: nonsteroidal anti‐inflammatory drug‐associated gastrointestinal complications—guidelines for prevention and treatment. Alimentary Pharmacology & Therapeutics 1999, 13: 1273-1285. PMID: 10540041, DOI: 10.1046/j.1365-2036.1999.00617.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalGastrointestinal DiseasesHumansPractice Guidelines as TopicRandomized Controlled Trials as TopicConceptsGastrointestinal complicationsPylori infectionSerious gastrointestinal complicationsH. pylori infectionHelicobacter pylori infectionProton pump inhibitorsLowest possible dosagePotential of treatmentNSAID therapyNSAID useAnalgesic therapyCorticosteroid useGastrointestinal bleedingUlcer diseaseAntisecretory agentsPump inhibitorsChronic ingestionPain relieversNSAIDsComplicationsPatientsExact associationPossible dosageRoutine testingPast history