2021
Genes, environment, and developmental timing: New insights from translational approaches to understand early origins of respiratory diseases
Gutierrez MJ, Perez GF, Gomez JL, Rodriguez‐Martinez C, Castro‐Rodriguez J, Nino G. Genes, environment, and developmental timing: New insights from translational approaches to understand early origins of respiratory diseases. Pediatric Pulmonology 2021, 56: 3157-3165. PMID: 34388306, PMCID: PMC8858026, DOI: 10.1002/ppul.25598.Peer-Reviewed Original ResearchMeSH KeywordsDNA MethylationEpigenesis, GeneticEpigenomicsHumansMicroRNAsRespiratory SystemRespiratory Tract DiseasesConceptsDevelopmental timingHistone modificationsPotential molecular mechanismsEpigenetic paradigmEpigenetic reprogrammingGenetic reprogrammingDevelopmental programDNA methylationMolecular mechanismsMolecular programmingReprogrammingEarly originsGenesLatest insightsNew insightsOmicsMethylationMicroRNAsHomeostasisLife-long consequencesInsightsTranslational approachRespiratory mucosaRespiratory diseaseCurrent evidence
2019
Epigenetics in Asthma
Gomez JL. Epigenetics in Asthma. Current Allergy And Asthma Reports 2019, 19: 56. PMID: 31776749, PMCID: PMC6986424, DOI: 10.1007/s11882-019-0886-y.BooksMeSH KeywordsAsthmaDNA MethylationEpigenesis, GeneticEpigenomicsGene SilencingHistonesHumansMicroRNAsConceptsChildhood asthmaCommon chronic respiratory diseasePurpose of ReviewAsthmaChronic respiratory diseasesUnderlying pathophysiological processesHuman asthmaAllergic inflammationAsthma endotypesHealthcare utilizationAsthma pathogenesisEpigenetic mechanismsImmune cellsRespiratory diseaseAsthmaHuman studiesPathophysiological processesSummaryThis reviewSpecific methylation signaturesNovel findingsMethylation signaturesCurrent literatureAdditional researchFuture studiesRegulatory roleEndotypes