2011
EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues
Kelly LM, Pereira JP, Yi T, Xu Y, Cyster JG. EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues. The Journal Of Immunology 2011, 187: 3026-3032. PMID: 21844396, PMCID: PMC3169736, DOI: 10.4049/jimmunol.1101262.Peer-Reviewed Original ResearchConceptsActivated B cellsB cellsAb responsesNonlymphoid tissuesCCR7-dependent mannerSecondary lymphoid organsDependent Ab responsesB cell migrationLigand activityCCR7 downregulationLymphoid organsFollicular regionsEBI2Outer follicleT zoneCD40 engagementCell linesLipid ligandsLymphoidCell migrationGene 2CellsTissueSerial movementsEarly wave
2005
Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients
Schwab SR, Pereira J, Matloubian M, Xu Y, Huang Y, Cyster JG. Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients. Science 2005, 309: 1735-1739. PMID: 16151014, DOI: 10.1126/science.1113640.Peer-Reviewed Original ResearchMeSH KeywordsAldehyde-LyasesAnimalsB-LymphocytesChemotaxis, LeukocyteEnzyme InhibitorsFood Coloring AgentsHematopoietic Stem CellsImidazolesImmunosuppressive AgentsLymphLymph NodesLymphoid TissueLymphopeniaLysophospholipidsMiceMice, Inbred C57BLPyridoxineReceptors, LysosphingolipidRNA InterferenceSphingosineThymus GlandT-LymphocytesVitamin B 6