2022
Prediction of Distant Metastases After Stereotactic Body Radiation Therapy for Early Stage NSCLC: Development and External Validation of a Multi-Institutional Model
Gao S, Jin L, Meadows H, Shafman T, Gross C, Yu J, Aerts H, Miccio J, Stahl J, Mak R, Decker R, Kann B. Prediction of Distant Metastases After Stereotactic Body Radiation Therapy for Early Stage NSCLC: Development and External Validation of a Multi-Institutional Model. Journal Of Thoracic Oncology 2022, 18: 339-349. PMID: 36396062, DOI: 10.1016/j.jtho.2022.11.007.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyEarly-stage NSCLCBody radiation therapyDistant metastasisStage NSCLCRadiation therapyHigh-risk patient subgroupsExternal validationPatient-level riskMulti-institutional databaseTime-dependent areaGray regression modelsRandom survival forest modelDM riskSystemic therapyPatient subgroupsIndividualized riskNSCLCPatientsDM ratesDiscriminatory performanceRandom survival forestTherapyInternal validationGood calibration
2021
Optimal Timing of SBRT for Treatment of Oligometastatic Disease: A Single Institution Retrospective Analysis
Gao S, Yu J, Park H, Decker R. Optimal Timing of SBRT for Treatment of Oligometastatic Disease: A Single Institution Retrospective Analysis. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e476-e477. DOI: 10.1016/j.ijrobp.2021.07.1324.Peer-Reviewed Original ResearchCurative-intent stereotactic body radiation therapyStereotactic body radiation therapyUpfront systemic therapyKarnofsky performance scoreProgression-free survivalSystemic therapyOverall survivalOligometastatic diseaseSequential therapyWorse survivalOligometastatic settingConcurrent therapyImproved survivalHigher Karnofsky performance scoreSingle-institution retrospective analysisOptimal timingCox proportional hazards modelExtracranial metastatic lesionsImproved overall survivalPrimary tumor locationMajority of patientsConcurrent systemic therapyMultivariate Cox analysisBody radiation therapyProportional hazards model
2020
Development and External Validation of a Nomogram to Predict Distant Metastases after Stereotactic Body Radiation Therapy in Early Stage Non-Small Cell Lung Cancer Patients
Gao S, Dosoretz A, Shafman T, Gross C, Yu J, Meadows H, Decker R, Mak R, Kann B. Development and External Validation of a Nomogram to Predict Distant Metastases after Stereotactic Body Radiation Therapy in Early Stage Non-Small Cell Lung Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e90. DOI: 10.1016/j.ijrobp.2020.07.1190.Peer-Reviewed Original ResearchDevelopment and Validation of a Deep Learning Algorithm to Predict Radiation Pneumonitis and Esophagitis Following Lung Stereotactic Body Radiation Therapy
Chang E, Du J, Decker R, Yu J, Park H, Aneja S. Development and Validation of a Deep Learning Algorithm to Predict Radiation Pneumonitis and Esophagitis Following Lung Stereotactic Body Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e14. DOI: 10.1016/j.ijrobp.2020.02.496.Peer-Reviewed Original ResearchLung stereotactic body radiation therapyStereotactic body radiation therapyBody radiation therapyRadiation pneumonitisRadiation therapyTrends in Use and Comparison of Stereotactic Body Radiation Therapy, Brachytherapy, and Dose-Escalated External Beam Radiation Therapy for the Management of Localized, Intermediate-Risk Prostate Cancer
Nguyen KA, Lee A, Patel SA, Chakravorty A, Yu JB, Kishan AU, Chang AJ. Trends in Use and Comparison of Stereotactic Body Radiation Therapy, Brachytherapy, and Dose-Escalated External Beam Radiation Therapy for the Management of Localized, Intermediate-Risk Prostate Cancer. JAMA Network Open 2020, 3: e2017144. PMID: 32970153, PMCID: PMC7516602, DOI: 10.1001/jamanetworkopen.2020.17144.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyBody radiation therapyRadiation therapyProstate cancerIntermediate-risk prostate cancerExternal beam radiation therapyManagement of LocalizedExternal beam radiotherapyUse of brachytherapyBeam radiation therapyCohort studyBeam radiotherapyTherapyDisease managementCancerBrachytherapyPatientsRadiotherapy
2019
An Externally Validated Nomogram to Predict Distant Metastases after Stereotactic Body Radiation Therapy in Early Stage Non-Small Cell Lung Cancer Patients
Gao S, Kann B, Dosoretz A, Shafman T, Gross C, Yu J, Decker R. An Externally Validated Nomogram to Predict Distant Metastases after Stereotactic Body Radiation Therapy in Early Stage Non-Small Cell Lung Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2019, 105: s145-s146. DOI: 10.1016/j.ijrobp.2019.06.146.Peer-Reviewed Original ResearchComparative Effectiveness of SBRT
Aneja S, Kumar R, Yu J. Comparative Effectiveness of SBRT. 2019, 415-424. DOI: 10.1007/978-3-030-16924-4_34.Peer-Reviewed Original ResearchStereotactic body radiation therapyAlternative treatment modalityBody radiation therapyComparative effectiveness studiesCost-effectiveness studiesLarge database analysisRetrospective seriesTreatment modalitiesRadiation therapySBRT treatmentComparative effectivenessEffectiveness studiesDatabase analysisStereotactic treatmentTreatmentPatientsLungTherapyProstateLiverBrainModerate hypofractionation and stereotactic body radiation therapy in the treatment of prostate cancer
Beckta J, Nosrati J, Yu J. Moderate hypofractionation and stereotactic body radiation therapy in the treatment of prostate cancer. Urologic Oncology Seminars And Original Investigations 2019, 37: 619-627. PMID: 30738746, DOI: 10.1016/j.urolonc.2019.01.015.Peer-Reviewed Original ResearchConceptsModerate hypofractionationRadiation therapyStereotactic body radiation therapyProstate cancer radiation therapyTreatment of prostate cancerCancer radiation therapyReduced duration of treatmentDuration of treatmentStandard of careCurative intentProstate cancerHigh dosesHypofractionationReduced durationDaily sessionsFractionation schemeTherapyEffective alternativeTreatmentProstatePatientsCancerDoseMonthsCare
2018
Systemic Therapy with Stereotactic Body Radiation Therapy (SBRT) for Early-Stage Non-Small Cell Lung Carcinoma (NSCLC): A Multi-institutional Analysis
Kann B, Miccio J, Stahl J, Verma V, Dosoretz A, Park H, Shafman T, Gross C, Yu J, Decker R. Systemic Therapy with Stereotactic Body Radiation Therapy (SBRT) for Early-Stage Non-Small Cell Lung Carcinoma (NSCLC): A Multi-institutional Analysis. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: s10-s11. DOI: 10.1016/j.ijrobp.2018.06.119.Peer-Reviewed Original Research
2017
Stereotactic Body Radiation Therapy for Oligometastatic Disease: A Multi-Institutional Retrospective Survival Analysis
Bui D, Magnuson W, Lester-Coll N, Qian J, Ross R, Soulos P, Shafman T, Dosoretz A, Evans S, Yu J, Gross C, Decker R. Stereotactic Body Radiation Therapy for Oligometastatic Disease: A Multi-Institutional Retrospective Survival Analysis. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e443. DOI: 10.1016/j.ijrobp.2017.06.1664.Peer-Reviewed Original ResearchStereotactic body radiation therapyRetrospective survival analysisBody radiation therapyOligometastatic diseaseDeep Neural Network to Predict Local Failure Following Stereotactic Body Radiation Therapy: Integrating Imaging and Clinical Data to Predict Outcomes
Aneja S, Shaham U, Kumar R, Pirakitikulr N, Nath S, Yu J, Carlson D, Decker R. Deep Neural Network to Predict Local Failure Following Stereotactic Body Radiation Therapy: Integrating Imaging and Clinical Data to Predict Outcomes. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s47. DOI: 10.1016/j.ijrobp.2017.06.120.Peer-Reviewed Original ResearchStereotactic body radiation therapyBody radiation therapyClinical dataRadiation therapyLocal failure
2016
A Biologically Effective Dose of ≥105 Gy Is Associated With Improved Overall Survival in Stage I Non-Small Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy
Stahl J, Ross R, Harder E, Mancini B, Soulos P, Dosoretz A, Finkelstein S, Shafman T, Husain Z, Evans S, Yu J, Gross C, Decker R. A Biologically Effective Dose of ≥105 Gy Is Associated With Improved Overall Survival in Stage I Non-Small Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: s174-s175. DOI: 10.1016/j.ijrobp.2016.06.438.Peer-Reviewed Original Research
2015
Higher Facility Case Volume of Stereotactic Body Radiation Therapy Is Associated With Improved Overall Survival in Clinical Stage I Non-Small Cell Lung Cancer
Park H, Wang E, Corso C, Rutter C, Wilson L, Kim A, Gross C, Yu J, Decker R. Higher Facility Case Volume of Stereotactic Body Radiation Therapy Is Associated With Improved Overall Survival in Clinical Stage I Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: s186-s187. DOI: 10.1016/j.ijrobp.2015.07.447.Peer-Reviewed Original ResearchSurvival Comparison of 3 Versus 4-5 Fractions for Stereotactic Body Radiation Therapy in Stage I Non-Small Cell Lung Cancer
Park H, Corso C, Rutter C, Kim A, Yu J, Husain Z, Decker R. Survival Comparison of 3 Versus 4-5 Fractions for Stereotactic Body Radiation Therapy in Stage I Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: s100. DOI: 10.1016/j.ijrobp.2015.07.240.Peer-Reviewed Original Research
2014
Cost Effectiveness Analysis of Stereotactic Body Radiation Therapy for Oligometastatic Non-Small Cell Lung Cancer Outcomes/Health Services Research
Lester-Coll N, Goldberg S, Yu J, Decker R. Cost Effectiveness Analysis of Stereotactic Body Radiation Therapy for Oligometastatic Non-Small Cell Lung Cancer Outcomes/Health Services Research. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s58. DOI: 10.1016/j.ijrobp.2014.08.271.Peer-Reviewed Original ResearchStereotactic body radiation therapyBody radiation therapyHealth services researchCost-effectiveness analysisRadiation therapyServices researchEffectiveness analysisTherapyCost Effectiveness of Biopsy Prior to Stereotactic Body Radiation Therapy (SBRT) for Screening-Detected FDG-Avid Lung Nodules
Rutter C, Lester-Coll N, Yu J, Decker R. Cost Effectiveness of Biopsy Prior to Stereotactic Body Radiation Therapy (SBRT) for Screening-Detected FDG-Avid Lung Nodules. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s137. DOI: 10.1016/j.ijrobp.2014.05.593.Peer-Reviewed Original ResearchStereotactic body radiation therapyBody radiation therapyRadiation therapyLung nodulesCost effectivenessTherapy