2009
A role for CMV infection in expansion of dysfunctional IL-7 receptor alpha low memory CD8+ T cell with aging. (83.11)
Lee W, Kang S, Lee S, Shah K, Kang I. A role for CMV infection in expansion of dysfunctional IL-7 receptor alpha low memory CD8+ T cell with aging. (83.11). The Journal Of Immunology 2009, 182: 83.11-83.11. DOI: 10.4049/jimmunol.182.supp.83.11.Peer-Reviewed Original ResearchLeukocyte Ig-like receptor-1Memory CD8T cellsAge-associated expansionCMV infectionChronic persistent viral infectionIL-7 receptor alpha chainT cell receptor repertoireHuman memory CD8TCR-mediated proliferationPersistent viral infectionCell receptor repertoireIg-like receptor-1Receptor alpha chainCytomegalovirus infectionIL-15Receptor beta chainElderly donorsCD8Young donorsViral infectionReceptor repertoireReceptor 1CMVExpression correlates
2008
Dual roles of IL‐15 in maintaining IL‐7 receptor alpha low CCR7− memory CD8+ T cells in humans via recovering the PI3K/AKT pathway
Kang I, Kim H, Hwang K. Dual roles of IL‐15 in maintaining IL‐7 receptor alpha low CCR7− memory CD8+ T cells in humans via recovering the PI3K/AKT pathway. The FASEB Journal 2008, 22: 846.18-846.18. DOI: 10.1096/fasebj.22.1_supplement.846.18.Peer-Reviewed Original ResearchPI3K/Akt pathwayMemory CD8Lower CCR7IL-15T cellsAkt pathwayIL-7 receptor alphaMemory T cell survivalIL-7 receptor alpha chainHuman peripheral bloodT cell survivalReceptor alpha chainHigher CCR7Peripheral CD8T cell receptor triggeringPeripheral bloodReceptor beta chainT-betCD8IL-7CCR7Effector functionsReceptor alphaEnhanced gene expressionProliferative function