IL-7Ralow memory CD8+ T cells are clonally anergic cells and defect in aerobic glycolysis pathway (HUM4P.274)
Sim J, Kim J, Seol M, Lee S, Cho B, Ko Y, Oh K, Lee D, Kim J, Park A, Kang I, Choi K, Kim H. IL-7Ralow memory CD8+ T cells are clonally anergic cells and defect in aerobic glycolysis pathway (HUM4P.274). The Journal Of Immunology 2015, 194: 122.5-122.5. DOI: 10.4049/jimmunol.194.supp.122.5.Peer-Reviewed Original ResearchMemory CD8T cellsIL-2 stimulationCD3/CD28 AbSubset of CD8TCR stimulationExpression of GATA3Aerobic glycolysis pathwayPMA/ionomycin treatmentDistal TCR signalingAnergic statusCD28 AbsPeripheral bloodHuman CD8IL-2C-myc expressionCD8IL-7Anergic cellsCalcium fluxHuman immunologyNF-AT1Nuclear translocationAerobic glycolysisIonomycin treatment