2023
Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application
Heerdt P, Martin-Flores M, Oakland H, Joseph P, Singh I. Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 1929-1937. PMID: 37422337, PMCID: PMC10529383, DOI: 10.1053/j.jvca.2023.06.011.Peer-Reviewed Original ResearchConceptsRight heart catheterizationHeart catheterizationDiastolic functionRV volumesBeat measuresDiagnostic right heart catheterizationReference standardRight ventricular contractilityEnd-diastolic pressurePressure waveform analysisEnd-systolic elastancePotential clinical utilityClinical applicationRV volume measurementsVolume measurementsRV contractilityRV systolicVentricular contractilityRV pressureBland-Altman analysisClinical utilityAnesthetized swineNitric oxideExperimental modelContractility
2019
A pressure-based single beat method for estimation of right ventricular ejection fraction: proof of concept
Heerdt PM, Kheyfets V, Charania S, Elassal A, Singh I. A pressure-based single beat method for estimation of right ventricular ejection fraction: proof of concept. European Respiratory Journal 2019, 55: 1901635. PMID: 31771999, PMCID: PMC7885179, DOI: 10.1183/13993003.01635-2019.Peer-Reviewed Original ResearchConceptsSingle-beat methodEjection fractionEnd-systolic ventricular elastanceRight ventricular ejection fractionRV pressure waveformsRight ventricular contractilityVentricular ejection fractionRV ejection fractionEes/EaVentricular contractilityCardiovascular decompensationVentricular elastancePressure waveform
2015
Exercise Intolerance in Pulmonary Hypertension
Singh I, Zappetti D. Exercise Intolerance in Pulmonary Hypertension. Clinical Pulmonary Medicine 2015, 22: 258-259. DOI: 10.1097/cpm.0000000000000122.Peer-Reviewed Original Research