2016
Sex-Based Selectivity of PPARγ Regulation in Th1, Th2, and Th17 Differentiation
Park HJ, Park HS, Lee JU, Bothwell AL, Choi JM. Sex-Based Selectivity of PPARγ Regulation in Th1, Th2, and Th17 Differentiation. International Journal Of Molecular Sciences 2016, 17: 1347. PMID: 27548145, PMCID: PMC5000743, DOI: 10.3390/ijms17081347.Peer-Reviewed Original ResearchConceptsEffector T cell differentiationT cellsT cell differentiationAdaptive immunityFemale T cellsMale T cellsPeroxisome proliferator-activated receptor gammaIL-17 productionDifferentiation of Th1PPARγ agonist pioglitazoneProliferator-activated receptor gammaNaïve T cellsSplenic T cellsMouse splenic T cellsImportant immune regulatorPioglitazone treatmentTfh responsesTh17 cellsAgonist pioglitazoneTreg functionAutoimmune diseasesEstrogen exposureImmune regulatorsCell differentiationTh1
2014
Insights into the Role of Follicular Helper T Cells in Autoimmunity
Park H, Kim D, Lim S, Kim W, Youn J, Choi Y, Choi J. Insights into the Role of Follicular Helper T Cells in Autoimmunity. Immune Network 2014, 14: 21-29. PMID: 24605077, PMCID: PMC3942504, DOI: 10.4110/in.2014.14.1.21.Peer-Reviewed Original ResearchTfh cell differentiationFollicular helper T cellsTfh cellsSystemic lupus erythematosusHelper T cellsT cellsAutoimmune diseasesB cellsBcl-6 expressionRheumatoid arthritisGerminal centersBCL-6Follicular regulatory T cellsB cell folliclesRegulatory T cellsNaïve T cellsMemory B cellsSurface moleculesCell differentiationImportant surface moleculesTfr cellsTreg cellsIL-21Lupus erythematosusPD-1