2023
Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center
Caraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center. JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.Commentaries, Editorials and Letters
2021
Falls in older adults after hospitalization for acute myocardial infarction
Goldstein DW, Hajduk AM, Song X, Tsang S, Geda M, McClurken JB, Tinetti ME, Krumholz HM, Chaudhry SI. Falls in older adults after hospitalization for acute myocardial infarction. Journal Of The American Geriatrics Society 2021, 69: 3476-3485. PMID: 34383963, PMCID: PMC8882265, DOI: 10.1111/jgs.17398.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionSerious fallsOlder patientsMyocardial infarctionRisk factorsAge 75Older adultsMedical record adjudicationLonger hospital stayMonths of dischargeProspective cohort studyMedical record reviewSelf-reported fallsAdults age 75Logistic regression analysisAcademic medical centerHospital stayCohort studyClinical factorsRecord reviewFunctional mobilityNew medicationsFall riskMedical CenterImpaired mobility
2016
Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers
Chen R, Desai NR, Ross JS, Zhang W, Chau KH, Wayda B, Murugiah K, Lu DY, Mittal A, Krumholz HM. Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers. The BMJ 2016, 352: i637. PMID: 26888209, PMCID: PMC4768882, DOI: 10.1136/bmj.i637.Peer-Reviewed Original ResearchConceptsAcademic medical centerInterventional clinical trialsClinical trialsMedical CenterStudy completionPrimary completion dateClinical trial resultsReporting of resultsSectional analysisInterventional trialsProportion of trialsTrial resultsTrialsMonthsPhase IIManual reviewLead investigatorUnited StatesProportionRate of publicationReportingCompletionPatientsCenter
2013
Quality of Discharge Practices and Patient Understanding at an Academic Medical Center
Horwitz LI, Moriarty JP, Chen C, Fogerty RL, Brewster UC, Kanade S, Ziaeian B, Jenq GY, Krumholz HM. Quality of Discharge Practices and Patient Understanding at an Academic Medical Center. JAMA Internal Medicine 2013, 173: 1715-1722. PMID: 23958851, PMCID: PMC3836871, DOI: 10.1001/jamainternmed.2013.9318.Peer-Reviewed Original ResearchConceptsPatient understandingAcademic medical centerDischarge instructionsPatients' perceptionsDischarge practicesDischarge careTransitional carePostdischarge interviewsMedical CenterProspective observational cohort studyDischarge care qualityPatients 65 yearsAcute coronary syndromeObservational cohort studyPatient-centered perspectiveCardiology appointmentsCoronary syndromeCohort studyPostdischarge careHeart failureDischarge planningMean agePrimary careDiet advicePatient's perspectiveComprehensive quality of discharge summaries at an academic medical center
Horwitz LI, Jenq GY, Brewster UC, Chen C, Kanade S, Van Ness P, Araujo KL, Ziaeian B, Moriarty JP, Fogerty RL, Krumholz HM. Comprehensive quality of discharge summaries at an academic medical center. Journal Of Hospital Medicine 2013, 8: 436-443. PMID: 23526813, PMCID: PMC3695055, DOI: 10.1002/jhm.2021.Peer-Reviewed Original ResearchConceptsDays of dischargeDischarge summariesAcute coronary syndromeProspective cohort studyAdvanced practice nursesImproved patient outcomesAcademic medical centerDischarge summary qualityCoronary syndromeCohort studyOutpatient cliniciansHeart failureOutside physiciansPractice nursesOutpatient physiciansPatient outcomesMedical CenterConsensus conferenceJoint CommissionMedical societiesPatientsSafe transitionTotalPhysiciansDays
2012
Discontinuation of Antihyperglycemic Therapy After Acute Myocardial Infarction: Medical Necessity or Medical Error?
Lovig KO, Horwitz L, Lipska K, Kosiborod M, Krumholz HM, Inzucchi SE. Discontinuation of Antihyperglycemic Therapy After Acute Myocardial Infarction: Medical Necessity or Medical Error? The Joint Commission Journal On Quality And Patient Safety 2012, 38: 403-407. PMID: 23002492, PMCID: PMC3534988, DOI: 10.1016/s1553-7250(12)38051-3.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLeft ventricular ejection fractionAntihyperglycemic therapyDiabetic patientsMyocardial infarctionMedical necessityOne-year mortalityDetailed chart reviewVentricular ejection fractionIschemic heart diseaseNational Medicare databaseMedical errorsAcademic medical centerQuality improvement opportunitiesChart reviewClinical characteristicsOlder patientsRecurrent hypoglycemiaEjection fractionMedicare databaseBlood glucoseHeart diseasePrincipal diagnosisCommunity hospitalMedical Center
2008
Use of Recommended Ambulatory Care Services: Is the Veterans Affairs Quality Gap Narrowing?
Ross JS, Keyhani S, Keenan PS, Bernheim SM, Penrod JD, Boockvar KS, Federman AD, Krumholz HM, Siu AL. Use of Recommended Ambulatory Care Services: Is the Veterans Affairs Quality Gap Narrowing? JAMA Internal Medicine 2008, 168: 950-958. PMID: 18474759, DOI: 10.1001/archinte.168.9.950.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAmbulatory CareBehavioral Risk Factor Surveillance SystemBreast NeoplasmsCholesterolColorectal NeoplasmsCounselingDiabetes MellitusDiabetic RetinopathyDisease ManagementDyslipidemiasFemaleHospitals, VeteransHumansInfluenza VaccinesMaleMiddle AgedPneumococcal VaccinesPreventive Health ServicesQuality of Health CareSmoking CessationUnited StatesVeteransConceptsVeterans Affairs Medical CenterAmbulatory care servicesInsured adultsCancer screeningCare servicesBehavior Risk Factor Surveillance SystemRisk Factor Surveillance SystemCardiovascular risk reductionColorectal cancer screeningChronic disease careBreast cancer screeningQuality improvement initiativesQuality of careUS health care systemInfectious disease preventionHealth care systemHealth Care Quality Improvement InitiativeEye examinationSelf-reported useDisease careCancer preventionMellitus managementMedical CenterAmbulatory careService use
2007
Changes in outcomes for internal medicine inpatients after work-hour regulations.
Horwitz LI, Kosiborod M, Lin Z, Krumholz HM. Changes in outcomes for internal medicine inpatients after work-hour regulations. Annals Of Internal Medicine 2007, 147: 97-103. PMID: 17548401, DOI: 10.7326/0003-4819-147-2-200707170-00163.Peer-Reviewed Original ResearchConceptsIntensive care unit utilizationLength of stayDrug-drug interactionsWork-hour regulationsNonteaching servicesHospital deathPharmacist interventionsReadmission ratesConsecutive patientsRetrospective cohort studyInternal medicine patientsInternal medicine inpatientsUnit utilizationAdverse drug-drug interactionsTeaching serviceAcademic medical centerCohort studyDischarge dispositionMedicine inpatientsMedicine patientsFatigue-related errorsMedical CenterRehabilitation facilityRate of dischargePatients
2003
A Critical Evaluation of Critical Pathways in Head and Neck Cancer
Yueh B, Weaver EM, Bradley EH, Krumholz HM, Heagerty P, Conley A, Sasaki CT. A Critical Evaluation of Critical Pathways in Head and Neck Cancer. JAMA Otolaryngology - Head & Neck Surgery 2003, 129: 89-95. PMID: 12525201, DOI: 10.1001/archotol.129.1.89.Peer-Reviewed Original ResearchConceptsNeck cancerCritical pathwaysLaryngectomy patientsManagement of headLow-volume proceduresLinear spline regression modelsPathway adoptionObservational cohortPathway patientsContemporary cohortHistorical cohortPathway implementationMedical CenterSpline regression modelsConfounding variablesLaryngectomyPatientsUtilization trendsCohortPrior reportsIndependent impactLOSSignificant differencesCancer
2000
Utilization and effectiveness of a weight-based heparin nomogram at a large academic medical center.
Balcezak TJ, Krumholz HM, Getnick GS, Vaccarino V, Lin ZQ, Cadman EC. Utilization and effectiveness of a weight-based heparin nomogram at a large academic medical center. The American Journal Of Managed Care 2000, 6: 329-38. PMID: 10977433.Peer-Reviewed Original ResearchConceptsWeight-based nomogramWeight-based heparin nomogramTherapeutic rangeTherapeutic thresholdHeparin nomogramIntravenous heparin therapyProportion of patientsProspective cohort analysisLarge academic medical centerInternal medicine serviceComputerized order entry systemAcademic medical centerEffective patient careSupratherapeutic aPTTsHeparin therapyConsecutive patientsOrder entry systemEfficacious therapyMedical CenterCohort analysisMedicine servicePatient carePhysician behaviorNomogramPatients
1999
Quality of care for patients hospitalized with heart failure at academic medical centers
Nohria A, Chen Y, Morton D, Walsh R, Vlasses P, Krumholz H. Quality of care for patients hospitalized with heart failure at academic medical centers. American Heart Journal 1999, 137: 1028-1034. PMID: 10347327, DOI: 10.1016/s0002-8703(99)70358-3.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionCongestive heart failureAcademic medical centerTime of dischargeStandard of careMedical CenterHeart failureACE inhibitorsAssessment of LVEFDiagnosis of CHFDaily weightEnzyme inhibitor therapyRetrospective chart reviewVentricular ejection fractionLarge clinical trialsPatient education guidelinesQuality of careHealth care policyChart reviewDietary counselingHospital dischargeEjection fractionInhibitor therapyTreatment guidelinesMedication compliance