2013
Natural ventilation reduces high TB transmission risk in traditional homes in rural KwaZulu-Natal, South Africa
Lygizos M, Shenoi SV, Brooks RP, Bhushan A, Brust J, Zelterman D, Deng Y, Northrup V, Moll AP, Friedland GH. Natural ventilation reduces high TB transmission risk in traditional homes in rural KwaZulu-Natal, South Africa. BMC Infectious Diseases 2013, 13: 300. PMID: 23815441, PMCID: PMC3716713, DOI: 10.1186/1471-2334-13-300.Peer-Reviewed Original ResearchConceptsTB transmission riskInfectious TB patientsTransmission riskTB patientsRural South AfricaDrug-resistant TBTB control effortsHealth care facilitiesPaucity of dataHousehold settingsRural KwaZulu-NatalPrevalent TBResistant TBTB transmissionCare facilitiesMultivariate analysisHIV areasVentilationAChSignificant decreaseWells-Riley equationPatientsRiskLow ventilationHour period
2010
Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community
Andrews JR, Shah NS, Weissman D, Moll AP, Friedland G, Gandhi NR. Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community. PLOS ONE 2010, 5: e15735. PMID: 21209951, PMCID: PMC3012092, DOI: 10.1371/journal.pone.0015735.Peer-Reviewed Original ResearchConceptsDrug-resistant tuberculosisTB treatment failureXDR-TBHIV prevalence settingsRisk factorsTreatment failureOdds ratioMDR/XDR-TBOnly significant risk factorRetrospective case-control studyDrug resistanceMDR-TB patientsSignificant risk factorsStrong risk factorMultivariate logistic regressionTB drug resistanceCase-control studyHigh HIV prevalence communitiesDemographic risk factorsDrug susceptibility testing methodsHIV prevalence communitiesTB settingsClinical deteriorationMDR-TBTB treatment
2004
Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care
Kozal MJ, Amico KR, Chiarella J, Schreibman T, Cornman D, Fisher W, Fisher J, Friedland G. Antiretroviral resistance and high-risk transmission behavior among HIV-positive patients in clinical care. AIDS 2004, 18: 2185-2189. PMID: 15577652, DOI: 10.1097/00002030-200411050-00011.Peer-Reviewed Original ResearchConceptsHIV-positive patientsTransmission risk behaviorsHIV transmission risk behaviorsViral loadUnprotected sexual eventsRisk behaviorsAntiretroviral therapyCopies/Clinical careHIV sexual transmission risk behaviorsUnprotected sexHigh-risk transmission behaviorsSexual transmission risk behaviorLower mental health scoresHIV transmission eventsUndetectable viral loadProportion of patientsHIV drug resistanceDrug-resistant HIVMental health scoresCross-sectional studyHIV transmission behaviorsDrug resistance dataAntiretroviral resistanceResistant HIV
1987
Oral findings in patients with acquired immunodeficiency syndrome
Phelan J, Saltzman B, Friedland G, Klein R. Oral findings in patients with acquired immunodeficiency syndrome. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1987, 64: 50-56. PMID: 3475658, DOI: 10.1016/0030-4220(87)90116-2.Peer-Reviewed Original ResearchConceptsImmunodeficiency syndromeKaposi's sarcomaBisexual menPerioral molluscum contagiosumExfoliative cheilitisGingival bleedingOral findingsConsecutive patientsHeterosexual patientsMolluscum contagiosumOral candidiasisCommon findingOral examinationUncertain causePatientsHairy tongueSarcomaLeukoplakiaSignificant differencesSubsequent examinationSyndromeAIDSMenExaminationFindingsA Prospective Longitudinal Study of Neuropsychological and Psychosocial Factors in Asymptomatic Individuals at Risk for Htlv-III/Lav Infection in a Methadone Program: Preliminary Findings
Silberstein C, McKegney F, O'dowd M, Selwyn P, Schoenbaum E, Drucker E, Feiner C, Cox C, Friedland G. A Prospective Longitudinal Study of Neuropsychological and Psychosocial Factors in Asymptomatic Individuals at Risk for Htlv-III/Lav Infection in a Methadone Program: Preliminary Findings. International Journal Of Neuroscience 1987, 32: 669-676. PMID: 3596916, DOI: 10.3109/00207458709043321.Peer-Reviewed Original ResearchConceptsProspective longitudinal studyWAIS similaritiesAssociative learning testHTLV-III/LAV infectionDigit Span ForwardLongitudinal studyImpaired neuropsychological functionLearning TestNeuropsychological functionPsychosocial measuresTest performanceFinger tappingPsychosocial factorsPsychological stressCognitive impairmentPreliminary findingsHTLV-III/LAVIntravenous drug abusersHigh-risk populationAbsence of AIDSDrug useDrug abusersAsymptomatic individualsMethadone programsUnivariate analysis
1984
AIDS Precautions for Other High-Risk Groups?
Klein R, Friedland G. AIDS Precautions for Other High-Risk Groups? Infection Control And Hospital Epidemiology 1984, 5: 466-466. PMID: 6567609, DOI: 10.1017/s0195941700060847.Peer-Reviewed Original ResearchOral Candidiasis in High-Risk Patients as the Initial Manifestation of the Acquired Immunodeficiency Syndrome
Klein R, Harris C, Small C, Moll B, Lesser M, Friedland G. Oral Candidiasis in High-Risk Patients as the Initial Manifestation of the Acquired Immunodeficiency Syndrome. New England Journal Of Medicine 1984, 311: 354-358. PMID: 6738653, DOI: 10.1056/nejm198408093110602.Peer-Reviewed Original ResearchConceptsT4/T8 ratioOral candidiasisT8 ratioImmunodeficiency syndromeOpportunistic infectionsHigh-risk patientsMajor opportunistic infectionIntravenous drug abusersAcquired Immunodeficiency SyndromeSerious opportunistic infectionsGeneralized lymphadenopathyInitial manifestationSimilar patientsKaposi's sarcomaHigh riskPatientsHealthy adultsCandidiasisLymphadenopathyBisexual menAIDSSarcomaSyndromeInfectionMonths