2019
Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison
Lampe FC, Rodger AJ, Burman W, Grulich A, Friedland G, Sadr WE, Neaton J, Corbelli GM, Emery S, Molina JM, Orkin C, Gatell J, Gerstoft J, Ruxrungtham K, de Souza M, Phillips AN. Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison. AIDS 2019, 33: 2337-2350. PMID: 31764099, PMCID: PMC6882545, DOI: 10.1097/qad.0000000000002359.Peer-Reviewed Original ResearchConceptsEarly antiretroviral treatmentHIV-serodifferent partnersAntiretroviral treatmentMonth 12Month 24CD4 cell countHIV-positive adultsSexual behaviorHIV infectiousnessImmediate armViral suppressionPrimary outcomeHigh prevalenceCondomless sexCell countMSMCells/Lower absolute levelsSexHeterosexual menTreatmentHeterosexualsArmAbsolute levelsPrevalence
2015
Transmission risk behaviour at enrolment in participants in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial
Rodger A, Lampe F, Grulich A, Fisher M, Friedland G, Phanuphak N, Bogner, Pereira L, Rietmeijer C, Burman W, Phillips A, Group I. Transmission risk behaviour at enrolment in participants in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial. HIV Medicine 2015, 16: 64-76. PMID: 25711325, PMCID: PMC4341939, DOI: 10.1111/hiv.12235.Peer-Reviewed Original ResearchConceptsAntiretroviral treatmentCondomless sexHIV-1 RNA copies/Risk behaviorsRegion of recruitmentSelf-reported risk behaviorsHIV viral loadHIV-positive participantsRNA copies/Transmission risk behaviorsHIV-positive peopleSubstantial proportionRecent sexual behaviorHeterosexual menSerodifferent partnersMedian ageRisk behavior questionnaireViral loadClinical statusLifestyle factorsBlack ethnicityCopies/Trial participantsStart StudyWhite ethnicity