2017
Turning the tide against tuberculosis
Padayatchi N, Naidu N, Friedland G, Naidoo K, Conradie F, Naidoo K, O’Donnell M. Turning the tide against tuberculosis. International Journal Of Infectious Diseases 2017, 56: 6-9. PMID: 28167256, DOI: 10.1016/j.ijid.2017.01.012.Peer-Reviewed Original Research
2009
Prognosis of patients with AIDS-associated Kaposi's sarcoma receiving antiretroviral therapy +/- chemotherapy in Kwazulu-Natal, South Africa: an analysis of 1-yr survival data from NCT00380770
Uldrick T, Mosam A, Shaik F, Friedland G, Skadden D, Jordaan J, Aboobaker J, Coovadia H. Prognosis of patients with AIDS-associated Kaposi's sarcoma receiving antiretroviral therapy +/- chemotherapy in Kwazulu-Natal, South Africa: an analysis of 1-yr survival data from NCT00380770. Infectious Agents And Cancer 2009, 4: p41. PMCID: PMC4261824, DOI: 10.1186/1750-9378-4-s2-p41.Peer-Reviewed Original Research
2007
Tuberculosis, drug resistance, and HIV/AIDS: A triple threat
Friedland G. Tuberculosis, drug resistance, and HIV/AIDS: A triple threat. Current Infectious Disease Reports 2007, 9: 252. PMID: 17430708, DOI: 10.1007/s11908-007-0039-7.Peer-Reviewed Original ResearchTB drug resistanceHIV/AIDSDrug-resistant tuberculosisDrug resistanceTB control programsRapid molecular diagnostic techniquesMultiple drug resistanceAvailable diagnostic technologiesMolecular diagnostic techniquesTB diagnosisWorldwide epidemicTreatment successTherapeutic strategiesTuberculosisTherapeutic agentsAIDSThird epidemicTreatmentDiagnosisDiagnostic techniquesControl programsDiagnostic technologiesEpidemicTriple threatUrgent need
2005
Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa
Mosam A, Cassol E, Page T, Bodasing U, Cassol S, Dawood H, Friedland GH, Scadden DT, Aboobaker J, Jordaan JP, Lalloo UG, Esterhuizen TM, Coovadia HM. Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa. AIDS 2005, 19: 441-443. PMID: 15750399, DOI: 10.1097/01.aids.0000161775.36652.85.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyKaposi's sarcomaCopies/Generic antiretroviral therapyUndetectable viral loadActive antiretroviral therapyGeneric antiretroviral drugsAntiretroviral efficacyViral loadAntiretroviral drugsLog10 declineClinical experienceSarcomaTherapySaharan AfricaSub-Saharan AfricaHIVPatientsAIDSBaseline
1995
Injection Drug Use and Human Immunodeficiency Virus Infection
Alcabes P, Friedland G. Injection Drug Use and Human Immunodeficiency Virus Infection. Clinical Infectious Diseases 1995, 20: 1467-1479. PMID: 7548494, DOI: 10.1093/clinids/20.6.1467.Peer-Reviewed Original ResearchConceptsSurveillance case definitionHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionDrug usersCase definitionInjection drugsVirus infectionPrevention (CDC) surveillance case definitionDiagnosis of AIDSInjection drug useInjection drug usersHigh mortality rateHIV diseaseHIV infectionDrug injectorsMortality rateDrug useNew casesNatural historyDisease controlAIDSDiagnostic facilitiesAIDS epidemicInitial epidemicLack of advocates
1994
Maturity of human immunodeficiency virus infection and incubation period of acquired immunodeficiency syndrome in injecting drug users
Alcabes P, Muñoz A, Vlahov D, Friedland G. Maturity of human immunodeficiency virus infection and incubation period of acquired immunodeficiency syndrome in injecting drug users. Annals Of Epidemiology 1994, 4: 17-26. PMID: 7911376, DOI: 10.1016/1047-2797(94)90038-8.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeBaltimoreCD4-Positive T-LymphocytesCohort StudiesConfidence IntervalsHIV InfectionsHIV SeroprevalenceHomosexualityHumansIncidenceLeukocyte CountLife TablesMaleModels, StatisticalNew York CityPlatelet CountRegression AnalysisSubstance Abuse, IntravenousSurvival RateTime FactorsConceptsHIV infectionDrug usersImmunodeficiency syndromeMedian timeCombined cohortHomosexual menHuman immunodeficiency virus (HIV) infectionHuman immunodeficiency virus (HIV) epidemicPercent of CD4Immunodeficiency virus infectionIncident HIV infectionProduct-limit methodMarkers of maturityHIV incubation distributionsPlatelet countVirus infectionLarge cohortSeroconversionCohortInfectionConfidence intervalsIncubation distributionAIDSVirus epidemicPopulation groups
1991
Demographic characteristics, drug use, and sexual behavior of i.v. drug user with AIDS in Bronx, New York.
Schrager L, Friedland G, Feiner C, Kahl P. Demographic characteristics, drug use, and sexual behavior of i.v. drug user with AIDS in Bronx, New York. Public Health Reports 1991, 106: 78-84. PMID: 1899944, PMCID: PMC1580205.Peer-Reviewed Original ResearchConceptsDrug usersDemographic characteristicsDrug useHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionIntravenous drug usersMontefiore Medical CenterMethadone maintenance programSharing of needlesInjection of drugsSexual behaviorDrug use behaviorsDrug use practicesHIV infectionImmunodeficiency syndromeVirus infectionMedical CenterEpidemiologic informationShooting galleriesCocaine useAIDSInjection episodesSexual practicesEarly ageInfectionSurvival differences in patients with AIDS.
Friedland G, Saltzman B, Vileno J, Freeman K, Schrager L, Klein R. Survival differences in patients with AIDS. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1991, 4: 144-53. PMID: 1987352.Peer-Reviewed Original ResearchConceptsPneumocystis carinii pneumoniaFavorable survivalCarinii pneumoniaMale sexYounger ageRisk behaviorsInitial AIDS diagnosisSingle medical centerIntravenous drug usePoint of diagnosisInitial AIDSMedian survivalAIDS diagnosisBlack raceSurvival differencesKaposi's sarcomaMedical CenterClinical carePatientsDrug useAIDSSurvivalDiagnosisPowerful predictorMonths
1990
Additional evidence for lack of transmission of HIV infection by close interpersonal (casual) contact
Friedland G, Kahl P, Saltzman B, Rogers M, Feiner C, Mayers M, Schable C, Klein R. Additional evidence for lack of transmission of HIV infection by close interpersonal (casual) contact. AIDS 1990, 4: 639-644. PMID: 2118767, DOI: 10.1097/00002030-199007000-00005.Peer-Reviewed Original ResearchConceptsHousehold contactsHIV infectionAIDS patientsClose interpersonal contactNon-sexual contactsPossibility of transmissionAdult patientsHIV antibodiesMedian durationMedian timeP24 antigenHIV transmissionPhysical examinationSerum antibodiesPatientsLast contactLack of transmissionLast evaluationInitial evaluationMonthsInfectionHIVSymptomsAntigenAIDS
1988
Increased risk of bacterial pneumonia in HIV-infected intravenous drug users without AIDS
Selwyn P, Feingold A, Hartel D, Schoenbaum E, Alderman M, Klein R, Friedland G. Increased risk of bacterial pneumonia in HIV-infected intravenous drug users without AIDS. AIDS 1988, 2: 267-272. PMID: 3140832, DOI: 10.1097/00002030-198808000-00005.Peer-Reviewed Original ResearchConceptsIntravenous drug usersIntravenous drug useBacterial pneumoniaHIV infectionDrug usersDrug useActive intravenous drug useCommunity-acquired bacterial pneumoniaCumulative yearly incidenceMethadone maintenance programSeronegative subjectsSeropositive patientsSeropositive subjectsStudy entryOpportunistic infectionsYearly incidencePneumoniaHemophilus influenzaeStreptococcus pneumoniaeSeropositivesHIVAIDSInfectionStudy periodIncidenceAIDS and Compassion
Friedland G. AIDS and Compassion. JAMA 1988, 259: 2898-2899. PMID: 3367458, DOI: 10.1001/jama.1988.03720190066034.Peer-Reviewed Original Research
1987
Oral findings in patients with acquired immunodeficiency syndrome
Phelan J, Saltzman B, Friedland G, Klein R. Oral findings in patients with acquired immunodeficiency syndrome. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1987, 64: 50-56. PMID: 3475658, DOI: 10.1016/0030-4220(87)90116-2.Peer-Reviewed Original ResearchConceptsImmunodeficiency syndromeKaposi's sarcomaBisexual menPerioral molluscum contagiosumExfoliative cheilitisGingival bleedingOral findingsConsecutive patientsHeterosexual patientsMolluscum contagiosumOral candidiasisCommon findingOral examinationUncertain causePatientsHairy tongueSarcomaLeukoplakiaSignificant differencesSubsequent examinationSyndromeAIDSMenExaminationFindingsSerologic, Immunologic, and Clinical Features of Parenteral Drug Users from Contrasting Populations
Shine D, Moll B, Emeson E, Spigland I, Harris C, Small C, Friedland G, Weiss S, Bodner A. Serologic, Immunologic, and Clinical Features of Parenteral Drug Users from Contrasting Populations. The American Journal Of Drug And Alcohol Abuse 1987, 13: 401-412. PMID: 2961253, DOI: 10.3109/00952998709001524.Peer-Reviewed Original ResearchConceptsT cell ratioParenteral drug usersDrug usersSeropositive patientsDevelopment of AIDSOral thrushClinical featuresHealthy outpatientsHTLV antibodiesClinical evidenceHTLV-IIIPatientsPositive ELISAAbnormal ratioAIDSWeight lossAntibodiesInpatientsDifferent risksLow ratioELISAMonthsOutpatientsImmunodeficiencySerology
1986
Lack of Transmission of HTLV-III/LAV Infection to Household Contacts of Patients with AIDS or AIDS-Related Complex with Oral Candidiasis
Friedland G, Saltzman B, Rogers M, Kahl P, Lesser M, Mayers M, Klein R. Lack of Transmission of HTLV-III/LAV Infection to Household Contacts of Patients with AIDS or AIDS-Related Complex with Oral Candidiasis. New England Journal Of Medicine 1986, 314: 344-349. PMID: 3456076, DOI: 10.1056/nejm198602063140604.Peer-Reviewed Original ResearchConceptsHTLV-III/LAVHousehold contactsOral candidiasisHuman T-cell lymphotropic virus type III/lymphadenopathy-associated virusHTLV-III/LAV infectionType III/lymphadenopathy-associated virusNonsexual household contactsLymphadenopathy-associated virusEvidence of infectionRisk of infectionRisk of transmissionNonsexual contactImmunodeficiency syndromeAIDS patientsPhysical examinationSerum antibodiesIndex patientsPatientsLack of transmissionSexual partnersAIDSInfectionFive-year-old childrenCandidiasisSame household
1985
Intravenous drug abusers and the acquired immunodeficiency syndrome (AIDS). Demographic, drug use, and needle-sharing patterns.
Friedland G, Harris C, Butkus-Small C, Shine D, Moll B, Darrow W, Klein R. Intravenous drug abusers and the acquired immunodeficiency syndrome (AIDS). Demographic, drug use, and needle-sharing patterns. JAMA Internal Medicine 1985, 145: 1413-7. PMID: 3875327, DOI: 10.1001/archinte.145.8.1413.Peer-Reviewed Original ResearchConceptsDrug abuser patientsIntravenous drug abusersDrug abusersImmunodeficiency syndromeNeedle sharingHomosexual menPutative AIDS agentPercent of patientsEvidence of AIDSBlood-borne routeDrug use patternsDrug use practicesARC patientsSexual habitsDrug usePatientsShooting galleriesSpread of AIDSAIDS agentsAIDSAIDS transmissionMale homosexualsDemographic characteristicsAbusersSyndrome
1984
Oral Candidiasis in High-Risk Patients as the Initial Manifestation of the Acquired Immunodeficiency Syndrome
Klein R, Harris C, Small C, Moll B, Lesser M, Friedland G. Oral Candidiasis in High-Risk Patients as the Initial Manifestation of the Acquired Immunodeficiency Syndrome. New England Journal Of Medicine 1984, 311: 354-358. PMID: 6738653, DOI: 10.1056/nejm198408093110602.Peer-Reviewed Original ResearchConceptsT4/T8 ratioOral candidiasisT8 ratioImmunodeficiency syndromeOpportunistic infectionsHigh-risk patientsMajor opportunistic infectionIntravenous drug abusersAcquired Immunodeficiency SyndromeSerious opportunistic infectionsGeneralized lymphadenopathyInitial manifestationSimilar patientsKaposi's sarcomaHigh riskPatientsHealthy adultsCandidiasisLymphadenopathyBisexual menAIDSSarcomaSyndromeInfectionMonths
1983
Acquired Immunodeficiency Syndrome Ophthalmic Manifestations in Ambulatory Patients
Rosenberg P, Uliss A, Friedland G, Harris C, Small C, Klein R. Acquired Immunodeficiency Syndrome Ophthalmic Manifestations in Ambulatory Patients. Ophthalmology 1983, 90: 874-878. PMID: 6314220, DOI: 10.1016/s0161-6420(83)80010-4.Peer-Reviewed Original ResearchConceptsAmbulatory patientsIntravenous drug abuseCotton wool spotsEpidemiology of AIDSCytomegalovirus retinitisOcular findingsOcular involvementOphthalmic manifestationsImmunodeficiency syndromePatientsMajor manifestationsDrug abuseManifestationsRetinitisSyndromeOphthalmologistsEpidemiologyAIDSFindingsImmunodeficiency in Female Sexual Partners of Men with the Acquired Immunodeficiency Syndrome
Harris C, Small C, Klein R, Friedland G, Moll B, Emeson E, Spigland I, Steigbigel N. Immunodeficiency in Female Sexual Partners of Men with the Acquired Immunodeficiency Syndrome. New England Journal Of Medicine 1983, 308: 1181-1184. PMID: 6221192, DOI: 10.1056/nejm198305193082001.Peer-Reviewed Original ResearchConceptsFemale sexual partnersMale patientsImmunodeficiency syndromeSexual partnersProdrome of AIDSSuppressor T cellsAcquired Immunodeficiency SyndromeImmunologic abnormalitiesProdromal illnessBiologic agentsT cellsDrug abusersHealthy adultsSyndromeCurrent outbreakDecreased ratioWomenPatientsHeterosexual menIllnessAbnormalitiesAIDSMenLymphadenopathyLymphopenia