2023
Racial, Ethnic, and Socioeconomic Differences in Food Allergies in the US
Jiang J, Warren C, Brewer A, Soffer G, Gupta R. Racial, Ethnic, and Socioeconomic Differences in Food Allergies in the US. JAMA Network Open 2023, 6: e2318162. PMID: 37314805, PMCID: PMC10267771, DOI: 10.1001/jamanetworkopen.2023.18162.Peer-Reviewed Original ResearchConceptsNon-Hispanic Black individualsNon-Hispanic white individualsParent-reported food allergyFood allergyWhite individualsBlack individualsEpinephrine autoinjector useFood allergy outcomesSurvey-weighted proportionsEmergency department visitsCommon food allergensFood allergy reactionsPopulation-based surveyCross-sectional survey studySimilar symptom presentationsLower ratesAutoinjector useDepartment visitsClinical outcomesPhysician diagnosisAllergy outcomesRepresentative sampleAllergy reactionsMAIN OUTCOMEPrevalence ratesThe emerging role of child life specialists in the pediatric food allergy clinic
Mathew M, Stahl U, Soffer G. The emerging role of child life specialists in the pediatric food allergy clinic. Annals Of Allergy Asthma & Immunology 2023, 131: 296-297. PMID: 37209837, DOI: 10.1016/j.anai.2023.05.013.Peer-Reviewed Original Research
2022
Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies
Maskey A, Wang Z, Chen X, Dunkin D, Yang N, Soffer G, Yuan Q, Li X. Computational analysis to define efficacy & molecular mechanisms of 7, 4’- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies. Frontiers In Immunology 2022, 13: 1015437. PMID: 36591238, PMCID: PMC9797535, DOI: 10.3389/fimmu.2022.1015437.Peer-Reviewed Original ResearchConceptsLevels of TNFIL-6Abdominal painEosinophilic esophagitisBiopsy samplesAbnormal bowel movementsTreatment of EoEMain treatment optionDihydroxy flavonesSignificant reductionTraditional Chinese medicine practiceDietary eliminationEoE therapyGE refluxSwallowed steroidsBowel movementsEoE patientsEsophageal dysfunctionGI symptomsEosinophilic inflammationImmunological mechanismsSteroid treatmentUpper endoscopyIgE productionChinese medicine practiceHealth disparities in pediatric food allergy
Tepler E, Wong KH, Soffer GK. Health disparities in pediatric food allergy. Annals Of Allergy Asthma & Immunology 2022, 129: 417-423. PMID: 35476967, DOI: 10.1016/j.anai.2022.04.022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPediatric food allergyFood allergyHealth disparitiesSocioeconomic disparitiesSocioeconomic statusOutcome of childrenLow socioeconomic statusGoogle Scholar databasesAllergen-free foodsLong-term managementAcute managementAllergy careOverall prevalenceFood assistance programsAllergyHealth outcomesScholar databasesGreater riskLiterature searchOriginal research articlesChildrenPossible interventionsPrevalenceCurrent literatureDiagnosis
2021
An integrative medicine review of primary prevention of allergy in pediatrics
Boolchandani H, Horwitz R, Soffer G. An integrative medicine review of primary prevention of allergy in pediatrics. Complementary Therapies In Medicine 2021, 58: 102695. PMID: 33636296, DOI: 10.1016/j.ctim.2021.102695.Peer-Reviewed Original ResearchConceptsAtopic diseasesAllergic diseasesPrimary preventionIntegrative medicineIntegrative medicine approachesLong-term outcomesNarrative review articlePrevention of diseaseMedicine ReviewsCounseling patientsPediatric populationAllergy preventionMedicine approachDiseasePreventionAllergyMedicineReview articlePatientsPregnancyPediatricsPrevalenceSensitization
2020
Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report.
Soffer G, Kaman K, Li XM. Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report. The Yale Journal Of Biology And Medicine 2020, 93: 685-688. PMID: 33380930, PMCID: PMC7757072.Peer-Reviewed Original ResearchConceptsTraditional Chinese medicineEosinophilic esophagitisChinese medicineQuality of lifeComplete remissionTopical steroidsFood eliminationTh2 cytokinesCase reportLabel useEoESuccessful managementEsophagitisTreatmentFurther modalitiesMedicineRemissionPatientsPathophysiologyCytokinesSteroidsPrevalenceCommunity Private Practice Clinical Experience with Peanut Oral Immunotherapy
Afinogenova Y, Rubin T, Patel S, Powell R, Gilo J, Denno M, Soffer G, Lee J, Mendelson L, Factor J. Community Private Practice Clinical Experience with Peanut Oral Immunotherapy. The Journal Of Allergy And Clinical Immunology In Practice 2020, 8: 2727-2735. PMID: 32247684, DOI: 10.1016/j.jaip.2020.03.016.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyPeanut-specific IgE levelsCutaneous adverse eventsRespiratory adverse eventsGastrointestinal adverse eventsAdverse eventsSpecific IgE levelsPeanut-allergic patientsOral immunotherapySystemic reactionsIgE levelsAdverse reactionsRetrospective chart reviewSpecific patient characteristicsMaintenance phaseAllergic profileGastrointestinal symptomsChart reviewImmunologic factorsPatient characteristicsPatient demographicsBlood pressureEosinophilic esophagitisAllergy testingPeanut allergy