2022
Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice
Maskey A, Srivastava K, Soffer G, Dunkin D, Yuan Q, Li X. Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice. Journal Of Inflammation Research 2022, 15: 5527-5540. PMID: 36176352, PMCID: PMC9514888, DOI: 10.2147/jir.s372449.Peer-Reviewed Original ResearchAirborne allergensNormal controlsEosinophilic inflammationEosinophilic esophagitisTh2 cytokinesAntigen-specific IgE levelsCommon chronic inflammatory diseaseImportant pathologic roleMild eosinophilic inflammationSevere eosinophilic esophagitisSevere eosinophilic inflammationIL-4/ILBronchoalveolar lavage fluidChronic inflammatory diseaseMulti-organ inflammationGene-deficient miceChemokine gene expressionIgA levelsIgE levelsIgG levelsSerum totalSpecific IgETotal IgAWT miceLavage fluid
2020
Community Private Practice Clinical Experience with Peanut Oral Immunotherapy
Afinogenova Y, Rubin T, Patel S, Powell R, Gilo J, Denno M, Soffer G, Lee J, Mendelson L, Factor J. Community Private Practice Clinical Experience with Peanut Oral Immunotherapy. The Journal Of Allergy And Clinical Immunology In Practice 2020, 8: 2727-2735. PMID: 32247684, DOI: 10.1016/j.jaip.2020.03.016.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyPeanut-specific IgE levelsCutaneous adverse eventsRespiratory adverse eventsGastrointestinal adverse eventsAdverse eventsSpecific IgE levelsPeanut-allergic patientsOral immunotherapySystemic reactionsIgE levelsAdverse reactionsRetrospective chart reviewSpecific patient characteristicsMaintenance phaseAllergic profileGastrointestinal symptomsChart reviewImmunologic factorsPatient characteristicsPatient demographicsBlood pressureEosinophilic esophagitisAllergy testingPeanut allergy