2015
Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial
Mentz RJ, Velazquez EJ, Metra M, McKendry C, Chiswell K, Fiuzat M, Givertz MM, Voors AA, Teerlink JR, O'Connor CM. Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial. Future Cardiology 2015, 11: 585-595. PMID: 26403536, PMCID: PMC5558519, DOI: 10.2217/fca.15.56.Peer-Reviewed Original ResearchConceptsPROTECT trialComparative effectivenessHigher blood urea nitrogenEffects of torsemideProspective randomized trialsHeart failure patientsBlood urea nitrogenGreater disease severityDays postdischargeFailure patientsHeart failureLoop diureticsRandomized trialsRenal hospitalizationUrea nitrogenDisease severityPatientsFurosemideInverse probabilityTorsemideTrialsDeathOutcomesHospitalizationDiureticsTemporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis
Ersboll M, Samad Z, Al Enezi F, Kisslo J, Schulte PJ, Shaw LK, Køber L, Harrison JK, Bashore T, Brennan M, Velazquez EJ. Temporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2015, 14: 103-109. PMID: 26214813, DOI: 10.1097/hpc.0000000000000048.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisProportion of patientsAortic stenosisSurgical riskHigh-risk aortic valve replacementDisease severityHealth care resource planningAortic valve replacementCalcific aortic stenosisHeart valve surgeryTime of referralTertiary hospital centerNumber of patientsNative aortic valveDuke University HospitalLogistic EuroSCOREValve surgeryValve replacementMedian ageReferral patternsUniversity HospitalAortic valveHospital CenterPatientsReferral
2008
Improvements in Signs and Symptoms During Hospitalization for Acute Heart Failure Follow Different Patterns and Depend on the Measurement Scales Used: An International, Prospective Registry to Evaluate the Evolution of Measures of Disease Severity in Acute Heart Failure (MEASURE-AHF)
Allen LA, Metra M, Milo-Cotter O, Filippatos G, Reisin LH, Bensimhon DR, Gronda EG, Colombo P, Felker GM, Dei L, Kremastinos DT, O'connor CM, Cotter G, Davison BA, Dittrich HC, Velazquez EJ. Improvements in Signs and Symptoms During Hospitalization for Acute Heart Failure Follow Different Patterns and Depend on the Measurement Scales Used: An International, Prospective Registry to Evaluate the Evolution of Measures of Disease Severity in Acute Heart Failure (MEASURE-AHF). Journal Of Cardiac Failure 2008, 14: 777-784. PMID: 18995183, PMCID: PMC3961584, DOI: 10.1016/j.cardfail.2008.07.188.Peer-Reviewed Original ResearchConceptsAcute heart failureHeart failurePatient-reported dyspneaProspective international cohortSymptoms of dyspneaPatient-reported symptomsVisual analog scaleMultiple clinical measuresAHF episodeAHF therapiesProspective registryEjection fractionPhysician assessmentAnalog scaleMean ageVAS measuresInternational cohortClinical measuresDyspneaPhysical signsDischarge decisionsDisease severitySymptomsDifferent patternsHospitalization