2022
Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis
Harrington C, Krishnan S, Mack CL, Cravedi P, Assis DN, Levitsky J. Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis. Hepatology 2022, 76: 1862-1879. PMID: 35611859, PMCID: PMC9796683, DOI: 10.1002/hep.32591.Peer-Reviewed Original ResearchConceptsAutoimmune hepatitisNormal serum transaminasesPediatric autoimmune hepatitisFirst-line treatmentAcute liver failureImmune cell phenotypesPredictors of responseHigh clinical valueNovel candidate biomarkersPersonalized therapeutic managementSystemic corticosteroidsCurrent regimensMedication titrationHistological activityMost patientsClinical courseLiver failureLiver injurySerum transaminasesMedication dosingTherapeutic managementUnclear etiologyHepatic fibrosisClinical valueElevated risk
2010
Testing and management of thrombocytopenia and coagulopathy in the pre- and postliver transplant patient.
Assis DN, Schilsky ML. Testing and management of thrombocytopenia and coagulopathy in the pre- and postliver transplant patient. Minerva Gastroenterology 2010, 56: 331-43. PMID: 21037549.Peer-Reviewed Original ResearchConceptsPost-transplant periodLiver diseaseAdvanced liver diseaseManagement of coagulopathyAcute liver failureManagement of thrombocytopeniaImportant clinical skillSuperimposed complicationsHepatic dysfunctionTransplant patientsLiver failureCoagulation changesTransplant periodPathophysiologic changesBlood productsCoagulation testingCoagulopathyThrombocytopeniaPatientsClinical skillsDiseasePreSepsisComplicationsDysfunction