2024
In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization
Kaushik R, McAvay G, Murphy T, Acampora D, Araujo K, Charpentier P, Chattopadhyay S, Geda M, Gill T, Kaminski T, Lee S, Li J, Cohen A, Hajduk A, Ferrante L. In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization. JAMA Network Open 2024, 7: e2419640. PMID: 38954414, PMCID: PMC11220565, DOI: 10.1001/jamanetworkopen.2024.19640.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumChart-Based Delirium Identification InstrumentOlder adultsFunctional disabilityCOVID-19 hospitalizationCognitive impairmentCohort studyAssociated with increased functional disabilityHospitalized older adultsIncreased functional disabilityAssociation of deliriumPostdischarge follow-upRisk of deliriumTertiary care systemFollow-upPresence of cognitive impairmentProspective cohort studyLogistic regression modelsOlder survivorsCare systemIncreasing cognitive impairmentMain OutcomesCOVID-19Hospital dischargePrimary outcomeAssociations of Social Support With Physical and Mental Health Symptom Burden After COVID-19 Hospitalization Among Older Adults
Lee S, McAvay G, Geda M, Chattopadhyay S, Acampora D, Araujo K, Charpentier P, Gill T, Hajduk A, Cohen A, Ferrante L. Associations of Social Support With Physical and Mental Health Symptom Burden After COVID-19 Hospitalization Among Older Adults. The Journals Of Gerontology Series A 2024, 79: glae092. PMID: 38558166, PMCID: PMC11059296, DOI: 10.1093/gerona/glae092.Peer-Reviewed Original ResearchConceptsLow social supportMental health symptomsSocial supportSymptom burdenHealth symptomsFollow-up assessmentCOVID-19 hospitalizationMedical Outcomes Study Social Support SurveyPhysical symptomsAssociation of social supportEdmonton Symptom Assessment SystemPatient Health Questionnaire-4Burden of physical symptomsMental health symptom burdenModified Edmonton Symptom Assessment SystemSocial Support SurveyParticipants' mean ageAssociated with higher burdenSupport SurveyOlder survivorsSymptom managementOlder AdultsMental healthHispanic ethnicityLongitudinal associations
2023
All the Lonely People: Social Isolation and Loneliness in Chronic Obstructive Pulmonary Disease
Ferrante L, Cohen A. All the Lonely People: Social Isolation and Loneliness in Chronic Obstructive Pulmonary Disease. Annals Of The American Thoracic Society 2023, 20: 1703-1704. PMID: 38038602, PMCID: PMC10704229, DOI: 10.1513/annalsats.202309-833ed.Commentaries, Editorials and LettersNavigating the COVID‐19 pandemic together: Discussions between persons with early‐stage dementia and their adult children
Ali T, Mroz E, Valeika S, Mendez E, Cohen A, Monin J. Navigating the COVID‐19 pandemic together: Discussions between persons with early‐stage dementia and their adult children. International Journal Of Geriatric Psychiatry 2023, 38: e5905. PMID: 36929513, PMCID: PMC10590087, DOI: 10.1002/gps.5905.Peer-Reviewed Original Research
2022
Rationale, Design, and Characteristics of the VALIANT (COVID‐19 in Older Adults: A Longitudinal Assessment) Cohort
Cohen A, McAvay G, Geda M, Chattopadhyay S, Lee S, Acampora D, Araujo K, Charpentier P, Gill T, Hajduk A, Ferrante L. Rationale, Design, and Characteristics of the VALIANT (COVID‐19 in Older Adults: A Longitudinal Assessment) Cohort. Journal Of The American Geriatrics Society 2022, 71: 832-844. PMID: 36544250, PMCID: PMC9877652, DOI: 10.1111/jgs.18146.Peer-Reviewed Original ResearchConceptsPatient-centered outcomesCOVID-19 hospitalizationCognitive impairmentPhysical functionOlder COVID-19 survivorsCOVID-19-related symptomsCOVID-19Older adultsIntensive care unitCOVID-19 survivorsPersistent cognitive impairmentSix-month followMost older adultsThird of participantsElectronic health recordsStepdown unitAcute illnessBurdensome symptomsCare unitSupplemental oxygenMedian lengthProspective studyMean ageBlack raceBaseline interviewBenefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia
Ouellet GM, O'Leary JR, Leggett CG, Skinner J, Tinetti ME, Cohen AB. Benefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia. Journal Of The American Geriatrics Society 2022, 71: 561-568. PMID: 36310367, PMCID: PMC9957933, DOI: 10.1111/jgs.18108.Peer-Reviewed Original ResearchConceptsNursing home residentsAtrial fibrillationAdvanced dementiaHome residentsStroke riskLong-stay nursing home residentsMedicare Part D claimsDementia-related mortalityGuideline-recommended thresholdHarms of anticoagulationRetrospective cohort studyMultivariable survival analysisValvular heart diseaseRisk of deathPart D claimsMonths of lifeMinimum Data SetAnticoagulant discontinuationAnticoagulated individualsMean CHAVASc scoreCause mortalityMultivariable adjustmentOral anticoagulantsCohort studyThe association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias
Gilstrap L, Cohen A, Ouellet GM, Goyal P, Gladders B, Flint D, Skinner J. The association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias. Journal Of The American Geriatrics Society 2022, 71: 404-413. PMID: 36240493, DOI: 10.1111/jgs.18086.Peer-Reviewed Original ResearchConceptsHigh riskBB useHeart failureAlzheimer's diseaseLong-term mortality ratesConcurrent Alzheimer's diseaseBeta-blocker useReduced ejection fractionMedicare Part ARisk/benefitBB therapyEjection fractionContemporary patientsHFrEFHigh prevalenceSimilar riskMortality ratePatientsCognitive impairmentMortalityDiseaseADRDRiskTherapyOutcomesEmergency department‐to‐community care transition barriers: A qualitative study of older adults
Gettel CJ, Serina PT, Uzamere I, Hernandez‐Bigos K, Venkatesh AK, Rising KL, Goldberg EM, Feder SL, Cohen AB, Hwang U. Emergency department‐to‐community care transition barriers: A qualitative study of older adults. Journal Of The American Geriatrics Society 2022, 70: 3152-3162. PMID: 35779278, PMCID: PMC9669106, DOI: 10.1111/jgs.17950.Peer-Reviewed Original ResearchConceptsCare transitionsOlder adultsClinical careImmediate post-discharge periodED discharge processEmergency clinical careEmergency department visitsPost-discharge periodAdverse health outcomesOutpatient clinical careDepartment visitsIntact patientsEmergency departmentHealth outcomesOlder adults' willingnessU.S. healthcare systemBaseline activityEffective interventionsIntervention developmentHealthcare systemAdultsCareAdults' willingnessSymptom explanationsEDAssociations between hospitalist physician workload, length of stay, and return to the hospital
Djulbegovic M, Chen K, Cohen AB, Heacock D, Canavan M, Cushing W, Agarwal R, Simonov M, Chaudhry SI. Associations between hospitalist physician workload, length of stay, and return to the hospital. Journal Of Hospital Medicine 2022, 17: 445-455. PMID: 35662410, PMCID: PMC9248905, DOI: 10.1002/jhm.12847.Peer-Reviewed Original ResearchConceptsLength of stayEmergency departmentPhysician workloadYale-New Haven HospitalMedian patient ageSeverity of illnessElectronic health record dataNumber of patientsHealth record dataWeekend admissionHospital daysPatient ageClinical outcomesObservational studyHospitalist serviceMAIN OUTCOMEPatient complexityHospitalist workloadSociodemographic factorsPatient encountersPatientsLogistic regressionMultilevel PoissonRecord dataOutcomesPerceived dementia risk and advance care planning among older adults
Lee YK, Fried TR, Costello DM, Hajduk AM, O'Leary JR, Cohen AB. Perceived dementia risk and advance care planning among older adults. Journal Of The American Geriatrics Society 2022, 70: 1481-1486. PMID: 35274737, PMCID: PMC9106856, DOI: 10.1111/jgs.17721.Peer-Reviewed Original ResearchConceptsAdvance care planningDementia riskOlder adultsTreatment preferencesCare planningForm of ACPMultivariable-adjusted logistic regressionDurable powerCross-sectional studyCommunity-dwelling adultsHealth behavior modelsMedical conditionsLower oddsACP activityCognitive impairmentLogistic regressionDementiaAdultsHealthcare decisionsSubstantial minorityLiving willsRiskRetirement StudyAppointmentsAssociationGuardianship Before and Following Hospitalization
Moye J, Cohen AB, Stolzmann K, Auguste EJ, Catlin CC, Sager ZS, Weiskittle RE, Woolverton CB, Connors HL, Sullivan JL. Guardianship Before and Following Hospitalization. HEC Forum 2022, 35: 271-292. PMID: 35072897, PMCID: PMC10281591, DOI: 10.1007/s10730-022-09469-9.Peer-Reviewed Original ResearchConceptsLength of stayHospital lengthComparison groupDate of admissionVeterans Healthcare AdministrationRetrospective cohortMedical complicationsCourt-appointed guardianNeuropsychiatric comorbiditiesUnnecessary hospitalizationStayPatientsEthics CommitteeMean lengthComorbiditiesHospitalizationGuardianship statusAppointmentsHealthcare administrationSeparate analysisGroupDaysPersonsGuardiansComplications
2021
Association of Social Isolation With Disability Burden and 1-Year Mortality Among Older Adults With Critical Illness
Falvey JR, Cohen AB, O’Leary J, Leo-Summers L, Murphy TE, Ferrante LE. Association of Social Isolation With Disability Burden and 1-Year Mortality Among Older Adults With Critical Illness. JAMA Internal Medicine 2021, 181: 1433-1439. PMID: 34491282, PMCID: PMC8424527, DOI: 10.1001/jamainternmed.2021.5022.Peer-Reviewed Original ResearchConceptsCritical illnessICU hospitalizationSocial isolation scoresOlder adultsICU admissionCohort studyPrimary outcomeDisability burdenSocial isolationCommunity-dwelling older adultsGreater disability burdenIsolation scoresPost-ICU disabilityObservational cohort studyAging Trends StudyICU stayMortality cohortHospital dischargeSecondary outcomesHospital admissionMedian ageIllness severityAdverse outcomesNational HealthHospitalization dataAnticoagulant Use for Atrial Fibrillation Among Persons With Advanced Dementia at the End of Life
Ouellet GM, Fried TR, Gilstrap LG, O’Leary J, Austin AM, Skinner JS, Cohen AB. Anticoagulant Use for Atrial Fibrillation Among Persons With Advanced Dementia at the End of Life. JAMA Internal Medicine 2021, 181: 1121-1123. PMID: 33970197, PMCID: PMC8111560, DOI: 10.1001/jamainternmed.2021.1819.Peer-Reviewed Original ResearchHow should advance care planning be done when a surrogate is making decisions?
Cohen AB, DeMartino ES. How should advance care planning be done when a surrogate is making decisions? Journal Of The American Geriatrics Society 2021, 69: 2103-2105. PMID: 34002373, PMCID: PMC8373712, DOI: 10.1111/jgs.17222.Commentaries, Editorials and LettersCharacteristics of Older Adults Who Cannot Identify a Healthcare Agent
Cohen AB, Paiva AL, Redding CA, Fried TR. Characteristics of Older Adults Who Cannot Identify a Healthcare Agent. Journal Of General Internal Medicine 2021, 37: 1313-1314. PMID: 33904034, PMCID: PMC8971249, DOI: 10.1007/s11606-021-06798-2.Peer-Reviewed Original ResearchDemographic Characteristics Driving Disparities in Receipt of Long-term Services and Supports in the Community Setting
Travers JL, Naylor MD, Coe NB, Meng C, Li F, Cohen AB. Demographic Characteristics Driving Disparities in Receipt of Long-term Services and Supports in the Community Setting. Medical Care 2021, 59: 537-542. PMID: 33827107, PMCID: PMC8119333, DOI: 10.1097/mlr.0000000000001544.Peer-Reviewed Original ResearchConceptsMinority older adultsWhite older adultsOlder adultsFunctional limitation scoresLimitation scoresUnadjusted analysesDaily livingFunctional limitationsNH careAlzheimer's diseaseCommunity settingsMarital statusAdultsAdult nursingFunctional needsRetirement StudyCareNursingMinority groupsGroupDisparitiesLong-term serviceDifferencesDementiaDisease
2020
Cognitively Impaired Older Persons' and Caregivers' Perspectives on Dementia‐Specific Advance Care Planning
Fried TR, Cohen AB, Harris JE, Moreines L. Cognitively Impaired Older Persons' and Caregivers' Perspectives on Dementia‐Specific Advance Care Planning. Journal Of The American Geriatrics Society 2020, 69: 932-937. PMID: 33216955, PMCID: PMC8300881, DOI: 10.1111/jgs.16953.Peer-Reviewed Original ResearchEnd-of-Life Care for Persons Under Guardianship
Moye J, Stolzmann K, Auguste EJ, Cohen AB, Catlin CC, Sager ZS, Weiskittle RE, Woolverton CB, Connors HL, Sullivan JL. End-of-Life Care for Persons Under Guardianship. Journal Of Pain And Symptom Management 2020, 62: 81-90.e2. PMID: 33212143, PMCID: PMC8124075, DOI: 10.1016/j.jpainsymman.2020.11.008.Peer-Reviewed Original ResearchConceptsPalliative care consultationVeterans Health AdministrationLife careCare consultationsHealth AdministrationIntensive care unit careIntensive care unitTransitions of careVeterans Healthcare AdministrationQuality of endHealth care challengesSurrogate decision makersSample of personsICU admissionUnit careCare unitAdverse outcomesPalliative careExtended lengthQuality endCareComparison groupHealth carePatient narrativesAdministrationGuardianship and End‐of‐Life Care for Veterans with Dementia in Nursing Homes
Cohen AB, Han L, OʼLeary JR, Fried TR. Guardianship and End‐of‐Life Care for Veterans with Dementia in Nursing Homes. Journal Of The American Geriatrics Society 2020, 69: 342-348. PMID: 33170957, PMCID: PMC7902349, DOI: 10.1111/jgs.16900.Peer-Reviewed Original ResearchConceptsDays of lifeHospital deathHigh-intensity treatmentMechanical ventilationTube placementHome residentsCardiopulmonary resuscitationNursing homesIntensive care unit admissionMinimum Data Set assessmentsCare unit admissionRetrospective cohort studyNursing home residentsHigh-intensity endMore nursing homesUnit admissionICU admissionCohort studySecondary outcomesPrimary outcomeHospital transferLife hospitalizationsSevere dementiaLife careDementia severitySucceeding in Aging Research During the Pandemic: Strategies for Fellows and Junior Faculty
Cohen AB, Parks AL, Whitson HE, Zieman S, Brown CJ, Boyd C, Covinsky KE, Steinman MA. Succeeding in Aging Research During the Pandemic: Strategies for Fellows and Junior Faculty. Journal Of The American Geriatrics Society 2020, 69: 8-11. PMID: 33047812, PMCID: PMC7675665, DOI: 10.1111/jgs.16868.Commentaries, Editorials and Letters