2020
FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C
So-Armah KA, Lim JK, Re V, Tate JP, Chang CH, Butt AA, Gibert CL, Rimland D, Marconi VC, Goetz MB, Ramachandran V, Brittain E, Long M, Nguyen KL, Rodriguez-Barradas MC, Budoff MJ, Tindle HA, Samet JH, Justice AC, Freiberg MS, Team V. FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C. Progress In Cardiovascular Diseases 2020, 63: 184-191. PMID: 32068085, PMCID: PMC7278895, DOI: 10.1016/j.pcad.2020.02.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsFemaleHealth StatusHeart FailureHepatitis CHIV InfectionsHIV Long-Term SurvivorsHumansIncidenceLiver CirrhosisMaleMiddle AgedPrognosisRisk AssessmentRisk FactorsSeverity of Illness IndexStroke VolumeTime FactorsUnited StatesVentricular Function, LeftVeterans HealthViral LoadConceptsType of HFIncident heart failureHeart failureHepatitis C statusAdvanced fibrosisLiver fibrosisEjection fractionHazard ratioC statusVeterans Aging Cohort StudyRisk of HFpEFLast clinic visitReduced ejection fractionAging Cohort StudyLiver fibrosis scoresPrevalent cardiovascular diseaseFirst HF eventProportional hazards modelIncident HFpEFHepatitis CClinic visitsCohort studyPrimary outcomeFibrosis scoreHF events
2017
FIB‐4 stage of liver fibrosis predicts incident heart failure among HIV‐infected and uninfected patients
So‐Armah K, Lim JK, Re V, Tate JP, Chang C, Butt AA, Gibert CL, Rimland D, Marconi VC, Goetz MB, Rodriguez‐Barradas M, Budoff MJ, Tindle HA, Samet JH, Justice AC, Freiberg MS, Team F. FIB‐4 stage of liver fibrosis predicts incident heart failure among HIV‐infected and uninfected patients. Hepatology 2017, 66: 1286-1295. PMID: 28543215, PMCID: PMC5609079, DOI: 10.1002/hep.29285.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusFibrosis/cirrhosisHIV/HCV statusAdvanced fibrosis/cirrhosisLiver fibrosisCHF eventsHCV statusFIB-4Hepatitis CAdvanced liver fibrosis/cirrhosisIncident CHFCongestive heart failure riskCardiovascular disease risk factorsVeterans Aging Cohort StudyProportional hazards regression modelsLiver fibrosis/cirrhosisIncident CHF eventsRisk of CHFFibrosis-4 indexIncident heart failureDisease risk factorsHeart failure riskAging Cohort StudyCardiovascular disease riskPrevalent cardiovascular disease
2012
HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation
Armah KA, McGinnis K, Baker J, Gibert C, Butt AA, Bryant KJ, Goetz M, Tracy R, Oursler KK, Rimland D, Crothers K, Rodriguez-Barradas M, Crystal S, Gordon A, Kraemer K, Brown S, Gerschenson M, Leaf DA, Deeks SG, Rinaldo C, Kuller LH, Justice A, Freiberg M. HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation. Clinical Infectious Diseases 2012, 55: 126-136. PMID: 22534147, PMCID: PMC3493182, DOI: 10.1093/cid/cis406.Peer-Reviewed Original ResearchConceptsBiomarkers of inflammationVeterans Aging Cohort StudyAltered coagulationMonocyte activationUninfected veteransCardiovascular diseaseElevated biomarkersComorbid conditionsHigh prevalenceCD4 cell countElevated IL-6Aging Cohort StudyOngoing HIV replicationPrevalent cardiovascular diseaseHIV-1 RNAHuman immunodeficiency virusCopies/mLElevated sCD14More dyslipidemiaCD4 countHepatitis CCohort studyComorbid diseasesCurrent smokingHIV infection
2010
The Association Between Alcohol Consumption and Prevalent Cardiovascular Diseases Among HIV-Infected and HIV-Uninfected Men
Freiberg MS, McGinnis KA, Kraemer K, Samet JH, Conigliaro J, Ellison R, Bryant K, Kuller LH, Justice AC. The Association Between Alcohol Consumption and Prevalent Cardiovascular Diseases Among HIV-Infected and HIV-Uninfected Men. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2010, 53: 247-253. PMID: 20009766, PMCID: PMC2858978, DOI: 10.1097/qai.0b013e3181c6c4b7.Peer-Reviewed Original ResearchConceptsPrevalent cardiovascular diseaseCardiovascular diseaseAlcohol consumptionHigh prevalenceAlcohol abuseHazardous drinkingRisk factorsOdds ratioModerate drinkingTraditional CVD risk factorsVeterans Aging Cohort StudyCVD risk factorsTraditional risk factorsAging Cohort StudyHIV-uninfected (HIV-) menHIV-InfectedSimilar HIVAntiretroviral therapyCD4 countCohort studyProspective cohortPast drinkersKidney diseaseHIVLogistic regression