2018
Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study.
Park LS, Tate JP, Sigel K, Brown ST, Crothers K, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Bedimo RJ, Justice AC, Dubrow R. Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study. Annals Of Internal Medicine 2018, 169: 87-96. PMID: 29893768, PMCID: PMC6825799, DOI: 10.7326/m16-2094.Peer-Reviewed Original ResearchConceptsLong-term viral suppressionViral suppressionLong-term suppressionCancer incidenceCancer riskHIV treatment successLow viral suppressionViral suppression statusProspective cohort studyT-cell countsEffect of CD4HIV-positive veteransCancer incidence ratesNational InstituteNational Cancer InstituteAIDS definingNon-AIDSUninfected veteransAntiretroviral therapyExcess cancer riskProspective cohortCohort studyUninfected personsIncidence rateTreatment success
2013
HIV Infection and the Risk of Acute Myocardial Infarction
Freiberg MS, Chang CC, Kuller LH, Skanderson M, Lowy E, Kraemer KL, Butt AA, Goetz M, Leaf D, Oursler KA, Rimland D, Barradas M, Brown S, Gibert C, McGinnis K, Crothers K, Sico J, Crane H, Warner A, Gottlieb S, Gottdiener J, Tracy RP, Budoff M, Watson C, Armah KA, Doebler D, Bryant K, Justice AC. HIV Infection and the Risk of Acute Myocardial Infarction. JAMA Internal Medicine 2013, 173: 614-622. PMID: 23459863, PMCID: PMC4766798, DOI: 10.1001/jamainternmed.2013.3728.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAcute myocardial infarctionRisk of AMIFramingham risk factorsUninfected veteransRisk factorsMyocardial infarctionAMI eventsHIV statusVeterans Aging Cohort Study Virtual CohortHIV-1 RNA levelsStandard Framingham risk factorsIncident acute myocardial infarctionIncidence of AMISubstance useBaseline cardiovascular diseaseCD4 cell countHepatitis C infectionBody mass indexHIV-1 RNACopies/mLHIV-positive veteransTime-updated analysisDecade of ageRace/ethnicity
2009
Impact of cigarette smoking on mortality in HIV-positive and HIV-negative veterans.
Crothers K, Goulet JL, Rodriguez-Barradas MC, Gibert CL, Oursler KA, Goetz MB, Crystal S, Leaf DA, Butt AA, Braithwaite RS, Peck R, Justice AC. Impact of cigarette smoking on mortality in HIV-positive and HIV-negative veterans. AIDS Education And Prevention 2009, 21: 40-53. PMID: 19537953, PMCID: PMC3118467, DOI: 10.1521/aeap.2009.21.3_supp.40.Peer-Reviewed Original ResearchConceptsHIV-negative veteransIncidence rate ratiosSmoking statusHIV-negative patientsSimilar mortality riskHIV-positive veteransComorbid diseasesCurrent smokingOverall mortalityCigarette smokingPoor outcomeMortality riskHIVPoisson regressionMortalitySmokingRate ratioVeteransDiseaseStudy of mechanismsLow levelsStatusSmokersPatientsCessation
2006
Hepatocellular Carcinoma and Non-Hodgkin's Lymphoma: The Roles of HIV, Hepatitis C Infection, and Alcohol Abuse
McGinnis KA, Fultz SL, Skanderson M, Conigliaro J, Bryant K, Justice AC. Hepatocellular Carcinoma and Non-Hodgkin's Lymphoma: The Roles of HIV, Hepatitis C Infection, and Alcohol Abuse. Journal Of Clinical Oncology 2006, 24: 5005-5009. PMID: 17075119, DOI: 10.1200/jco.2006.05.7984.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceHIV-negative veteransAbuse/dependenceHIV-positive veteransIncident rate ratiosHepatocellular carcinomaGreater riskVeterans Affairs Healthcare SystemFirst HIV diagnosisHepatitis C infectionPresence of HCVRole of HIVNinth Revision codesNon-Hodgkin lymphomaRelationship of HIVHeavy alcohol useHigher relative incidencePoisson regression modelsC infectionHCV infectionHepatitis CHIV diagnosisHIV statusHodgkin's lymphomaRevision codesIntoxication Before Intercourse and Risky Sexual Behavior in Male Veterans With and Without Human Immunodeficiency Virus Infection
Cook RL, McGinnis KA, Kraemer KL, Gordon AJ, Conigliaro J, Maisto SA, Samet JH, Crystal S, Rimland D, Bryant KJ, Braithwaite RS, Justice AC. Intoxication Before Intercourse and Risky Sexual Behavior in Male Veterans With and Without Human Immunodeficiency Virus Infection. Medical Care 2006, 44: s31-s36. PMID: 16849966, DOI: 10.1097/01.mlr.0000223710.35008.d9.Peer-Reviewed Original ResearchConceptsHIV-positive veteransInconsistent condom useHuman immunodeficiency virus (HIV) infectionHIV-negative veteransImmunodeficiency virus infectionRisky sexual behaviorMale veteransCondom useVirus infectionSexual behaviorSexual partnersVeterans Aging CohortHIV-positive menMeasures of drugMore partnersHIV infectionHIV-positiveOutpatient clinicMeasures of alcoholAging CohortDrug useAlcohol useLast intercourseIntoxicationPast year
2005
The Impact of Cigarette Smoking on Mortality, Quality of Life, and Comorbid Illness Among HIV‐Positive Veterans
Crothers K, Griffith TA, McGinnis KA, Rodriguez‐Barradas M, Leaf DA, Weissman S, Gibert CL, Butt AA, Justice AC. The Impact of Cigarette Smoking on Mortality, Quality of Life, and Comorbid Illness Among HIV‐Positive Veterans. Journal Of General Internal Medicine 2005, 20: 1142-1145. PMID: 16423106, PMCID: PMC1490270, DOI: 10.1111/j.1525-1497.2005.0255.x.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseQuality of lifeHIV-positive patientsImpact of smokingPhysical component summaryHIV-positive veteransCurrent smokersRespiratory symptomsBacterial pneumoniaActive antiretroviral therapyCD4 cell countHIV RNA levelsProspective observational studyObstructive pulmonary diseaseShort Form-12National VA databasesRace/ethnicityAntiretroviral therapyComorbid illnessesComponent summaryHIV infectionPatient questionnairePulmonary diseaseChart extractionCigarette smoking
2004
Psychiatric and neurocognitive disorders among HIV-positive and negative veterans in care
Justice AC, McGinnis KA, Atkinson JH, Heaton RK, Young C, Sadek J, Madenwald T, Becker JT, Conigliaro J, Brown ST, Rimland D, Crystal S, Simberkoff M. Psychiatric and neurocognitive disorders among HIV-positive and negative veterans in care. AIDS 2004, 18: 49-59. PMID: 15075498, DOI: 10.1097/00002030-200401001-00008.Peer-Reviewed Original ResearchConceptsHIV-negative subjectsHIV-positive subjectsNeurocognitive disordersDepressive symptomsAlcohol abuseDrug abuseHIV-negative veteransVeterans Aging CohortGeneral medicine clinicHIV-positive veteransSymptoms of depressionMemory problemsConvenience subsetOlder HIVHIV infectionMedicine clinicPsychiatric testingHigh prevalencePatient reportsSubstantial prevalenceGreater prevalenceAvailable measuresAging CohortNeurocognitive problemsInfectious diseases
2003
How Harmful Is Hazardous Alcohol Use and Abuse in HIV Infection: Do Health Care Providers Know Who Is at Risk?
Conigliaro J, Gordon AJ, McGinnis KA, Rabeneck L, Justice AC. How Harmful Is Hazardous Alcohol Use and Abuse in HIV Infection: Do Health Care Providers Know Who Is at Risk? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 33: 521-525. PMID: 12869842, DOI: 10.1097/00126334-200308010-00014.Peer-Reviewed Original ResearchConceptsHealth care providersHIV disease progressionCare providersAlcohol diagnosisDisease progressionTransaminase levelsHIV infectionViral loadAlcohol useBinge drinkersHazardous drinkingHealth care providers' awarenessElevated mean corpuscular volumeSevere HIV infectionCD4 cell countPercent of patientsUndetectable viral loadAspartate transaminase levelsDetectable viral loadProspective cohort studyAlcohol Use Disorders Identification TestCare providers' awarenessHIV-positive veteransAlcohol problemsExcessive alcohol use