2020
Using longitudinal PSA values and machine learning for predicting progression of early stage prostate cancer in veterans.
Danciu I, Erwin S, Agasthya G, Janet T, McMahon B, Tourassi G, Justice A. Using longitudinal PSA values and machine learning for predicting progression of early stage prostate cancer in veterans. Journal Of Clinical Oncology 2020, 38: e17554-e17554. DOI: 10.1200/jco.2020.38.15_suppl.e17554.Peer-Reviewed Original ResearchDisease progressionClinical data warehouseLast PSAPSA valuesEarly-stage prostate cancerSEER summary stageTime of diagnosisAppropriate treatment planProstate cancer patientsStage prostate cancerHealth record dataProstate cancer diagnosisEvidence-based approachClinical decision supportCancer RegistryRadium-223Cancer patientsGleason scoreSummary stageLaboratory valuesProstate cancerTreatment planOutcome predictionDiagnosisPSA
2019
HIV RNA, CD4+ Percentage, and Risk of Hepatocellular Carcinoma by Cirrhosis Status
Torgersen J, Kallan MJ, Carbonari DM, Park LS, Mehta RL, D’Addeo K, Tate JP, Lim JK, Goetz MB, Rodriguez-Barradas MC, Gibert CL, Bräu N, Brown ST, Roy JA, Taddei TH, Justice AC, Re V. HIV RNA, CD4+ Percentage, and Risk of Hepatocellular Carcinoma by Cirrhosis Status. Journal Of The National Cancer Institute 2019, 112: 747-755. PMID: 31687755, PMCID: PMC7357318, DOI: 10.1093/jnci/djz214.Peer-Reviewed Original ResearchConceptsRisk of HCCHigher HIV RNAHCC risk factorsHIV RNAHIV viremiaHepatocellular carcinomaBaseline cirrhosisCirrhosis statusCohort studyRisk factorsCell percentageVeterans Aging Cohort StudyDevelopment of HCCCurrent HIV RNADetectable HIV viremiaHepatitis C coinfectionAging Cohort StudyDiagnosis of cirrhosisLonger durationDetectable HIVLow CD4C coinfectionCurrent CD4Hazard ratioCancer Registry
2014
Cancer Incidence in HIV-Infected Versus Uninfected Veterans: Comparison of Cancer Registry and ICD-9 Code Diagnoses
Park LS, Tate JP, Rodriguez-Barradas MC, Rimland D, Goetz MB, Gibert C, Brown ST, Kelley MJ, Justice AC, Dubrow R. Cancer Incidence in HIV-Infected Versus Uninfected Veterans: Comparison of Cancer Registry and ICD-9 Code Diagnoses. Journal Of AIDS & Clinical Research 2014, 05: 1000318. PMID: 25580366, PMCID: PMC4285627, DOI: 10.4172/2155-6113.1000318.Peer-Reviewed Original ResearchVeterans Affairs Central Cancer RegistryVeterans Aging Cohort StudyStandardized incidence ratiosIncidence rate ratiosUninfected veteransIncident cancerCancer RegistryCancer riskICD-9End Results (SEER) ratesHigh positive predictive valueAging Cohort StudyICD-9 code diagnosisCentral Cancer RegistryICD-9 diagnosisPositive predictive valueFalse-positive diagnosesHIV/AIDSElevated cancer riskRace/ethnicityCohort studyProspective cohortHIV statusIncidence ratiosCancer burden
2012
HIV as an independent risk factor for incident lung cancer
Sigel K, Wisnivesky J, Gordon K, Dubrow R, Justice A, Brown ST, Goulet J, Butt AA, Crystal S, Rimland D, Rodriguez-Barradas M, Gibert C, Park LS, Crothers K. HIV as an independent risk factor for incident lung cancer. AIDS 2012, 26: 1017-1025. PMID: 22382152, PMCID: PMC3580210, DOI: 10.1097/qad.0b013e328352d1ad.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosIndependent risk factorUninfected patientsLung cancerSimilar HIVHIV infectionSurveillance biasRisk factorsIncidence rateVeterans Aging Cohort Study Virtual CohortVeterans Affairs Central Cancer RegistryChronic obstructive pulmonary diseaseIncident lung cancerObstructive pulmonary diseaseCentral Cancer RegistryLung cancer stageSimilar stage distributionRace/ethnicityExcess smokingMultivariable adjustmentAnalytic cohortPulmonary diseaseBacterial pneumoniaCancer RegistryPotential confounders