2021
Pulmonary Hypertension in Obstructive Sleep Apnea
Mohsenin V. Pulmonary Hypertension in Obstructive Sleep Apnea. 2021, 69-76. DOI: 10.1007/978-3-030-57942-5_6.Peer-Reviewed Original ResearchMean pulmonary artery pressurePulmonary hypertensionChronic obstructive pulmonary diseaseMild pulmonary arterial hypertensionPulmonary artery pressurePulmonary arterial hypertensionThird of patientsChronic lung diseaseObstructive pulmonary diseaseObstructive sleep apneaTreatment of OSADaytime hypoxemiaArterial hypertensionArtery pressureObesity hypoventilationHeart failurePulmonary diseaseSleep apneaLung diseaseHypertensionOSAPatientsDiseaseCurrent definitionHypoxemia
2016
Chitinase-3-like protein-1 (YKL-40) as a marker of endothelial dysfunction in obstructive sleep apnea
Jafari B, Mohsenin V. Chitinase-3-like protein-1 (YKL-40) as a marker of endothelial dysfunction in obstructive sleep apnea. Sleep Medicine 2016, 25: 87-92. PMID: 27823723, DOI: 10.1016/j.sleep.2016.08.001.Peer-Reviewed Original ResearchConceptsHypertensive OSAObstructive sleep apneaFlow-mediated vasodilationEndothelial dysfunctionYKL-40Sleep apneaEndothelial-dependent vasodilatory capacityNormotensive OSAChitinase-3-like protein 1Sleep-disordered breathingCharacteristic curve analysisChitinase-3-like proteinHypertension independentVasodilatory capacityCardiovascular morbidityEndothelial functionHypertension statusRisk factorsPrevalent disorderHypertensionNegative correlationDysfunctionPotential biomarkersSignificant negative correlationCurve analysis
2015
Pulmonary Hypertension in Obstructive Sleep Apnea: Is it Clinically Significant? a Critical Analysis of the Association and Pathophysiology
Kholdani C, Fares WH, Mohsenin V. Pulmonary Hypertension in Obstructive Sleep Apnea: Is it Clinically Significant? a Critical Analysis of the Association and Pathophysiology. Pulmonary Circulation 2015, 5: 220-227. PMID: 26064448, PMCID: PMC4449234, DOI: 10.1086/679995.Peer-Reviewed Original ResearchObstructive sleep apneaPulmonary hypertensionPulmonary venous hypertensionVenous hypertensionSleep apneaSetting of OSAPulmonary artery pressurePoor prognostic signHypoxic pulmonary vasoconstrictionMajority of patientsLeft heart dysfunctionAberrant vascular remodelingQuality of lifeResult of apneaVascular cell proliferationArtery pressurePulmonary vasoconstrictionEjection fractionIntermittent hypoxiaPrognostic signHeart dysfunctionLeft heartHigh prevalenceHypertensionVascular remodeling
2012
Rehabilitation of stroke and sleep apnea
Jafari B, Mohsenin V. Rehabilitation of stroke and sleep apnea. 2012, 127-138. DOI: 10.1017/cbo9781139061056.013.Peer-Reviewed Original ResearchManagement of sleepSleep apneaSleep disordersPrimary care practitionersRehabilitation of strokeClinical evidenceVascular disturbancesStroke disorderVascular disordersCardiovascular diseasePrevalent conditionVascular pathologyAccurate diagnosisStrokeSleepDiagnosisDisordersApneaBetter diagnosisHypertensionPulmonologistsNeurologistsCardiologistsManagementDisease
2011
Role Of Nitric Oxide-Dependent Vasodilatation And Carbon Monoxide In Developing Hypertension In Obstructive Sleep Apnea (OSA)
Jafari B, Mohsenin V. Role Of Nitric Oxide-Dependent Vasodilatation And Carbon Monoxide In Developing Hypertension In Obstructive Sleep Apnea (OSA). 2011, a2218-a2218. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2218.Peer-Reviewed Original Research
2001
Sleep-Related Breathing Disorders and Risk of Stroke
Mohsenin V. Sleep-Related Breathing Disorders and Risk of Stroke. Stroke 2001, 32: 1271-1278. PMID: 11387486, DOI: 10.1161/01.str.32.6.1271.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersTransient ischemic attackRisk of strokeBreathing disordersRisk factorsSleep apnea disorderIschemic attackApnea disorderHematologic changesHigh prevalenceNormal sleep stateModifiable risk factorsPresence of hypertensionRecent large epidemiological studiesPossible pathogenetic mechanismsLarge epidemiological studiesDiurnal hypertensionCerebral perfusionSignificant morbidityCerebral hemodynamicsPathogenetic mechanismsEpidemiological studiesStrokeHypertensionPatients
2000
Sleep-related breathing disorders and cardiovascular disease
Roux F, D’Ambrosio C, Mohsenin V. Sleep-related breathing disorders and cardiovascular disease. The American Journal Of Medicine 2000, 108: 396-402. PMID: 10759096, DOI: 10.1016/s0002-9343(00)00302-8.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersBreathing disordersRisk factorsUpper airway resistance syndromeIndependent risk factorMajority of patientsMajor health problemPulmonary hypertensionSympathetic toneBaroreflex controlIntermittent hypoxiaExcessive daytimeSleep apneaCerebrovascular diseaseResistance syndromeEarly recognitionCardiovascular functionCardiovascular diseaseEpidemiologic studiesNeuropsychological dysfunctionHealth problemsMemory impairmentPoor work performanceDisordersHypertension