2003
Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations
Safitri I, Jalloh A, Tantular I, Pusarawati S, Win T, Liu Q, Ferreira M, Dachlan Y, Horii T, Kawamoto F. Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations. Parasitology International 2003, 52: 117-131. PMID: 12798923, DOI: 10.1016/s1383-5769(02)00088-0.Peer-Reviewed Original Research
2002
Wide distribution of Plasmodium ovale in Myanmar
Win T, Lin K, Mizuno S, Zhou M, Liu Q, Ferreira M, Tantular I, Kojima S, Ishii A, Kawamoto F. Wide distribution of Plasmodium ovale in Myanmar. Tropical Medicine And International Health 2002, 7: 231-239. PMID: 11903985, DOI: 10.1046/j.1365-3156.2002.00857.x.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionPlasmodium ovaleP. ovaleP. ovale-infected patientsThin smearsPCR-positive patientsPlasmodium ovale infectionNested polymerase chain reactionHuman malaria parasiteSingle-species infectionsOvale infectionsP. malariaeQuadruple infectionsP. vivaxBlood samplesP. falciparumOvaleMalaria parasitesPatientsPlasmodium speciesInfectionChain reactionMolecular diagnosis
2000
Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates.
Liu Q, Ferreira M, Ndawi B, Ohmae H, Adagu I, Morikawa T, Horii T, Isomura S, Kawamoto F. Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates. The Southeast Asian Journal Of Tropical Medicine And Public Health 2000, 31: 808-17. PMID: 11414433.Peer-Reviewed Original Research
1999
How Prevalant are Plasmodium ovale and P. malariae in East Asia?
Kawamoto F, Liu Q, Ferreira M, Tantular I, Kawamoto F, Liu Q, Ferreira M, Tantular I. How Prevalant are Plasmodium ovale and P. malariae in East Asia? Trends In Parasitology 1999, 15: 422-426. PMID: 10481157, DOI: 10.1016/s0169-4758(99)01511-2.Peer-Reviewed Original ResearchConceptsPlasmodium ovaleMalaria parasitesIntense malaria transmissionHuman malaria parasiteAlternative diagnostic methodPlasmodium malariaeP. malariaeLow prevalenceMalaria speciesMalaria transmissionAcridine orange stainingMalariaeDiagnostic methodsOrange stainingOvalePrevalenceMorphological criteriaPCRAcridine orangeParasites
1998
Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania.
Ferreira M, Liu Q, Kimura M, Ndawi B, Tanabe K, Kawamoto F. Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania. Journal Of Parasitology 1998, 84: 1286-9. PMID: 9920333, DOI: 10.2307/3284693.Peer-Reviewed Original ResearchConceptsMerozoite surface protein 1MSP-1 gene typesSurface protein 1Type-specific polymerase chain reactionMajor malaria vaccine candidatePlasmodium falciparum infectionProtein 1Malaria vaccine candidateMsp-1 geneP. falciparum populationsMost patientsFalciparum infectionPolymerase chain reactionDistinct parasite populationsVaccine candidatesClinical isolatesAllelic typesGene typesPlasmodium falciparumNorthern TanzaniaChain reactionPatientsEpidemiological consequencesRecent findingsParasite populationsSequence Variation in the Small-Subunit rRNA Gene of Plasmodium malariae and Prevalence of Isolates with the Variant Sequence in Sichuan, China
Liu Q, Zhu S, Mizuno S, Kimura M, Liu P, Isomura S, Wang X, Kawamoto F. Sequence Variation in the Small-Subunit rRNA Gene of Plasmodium malariae and Prevalence of Isolates with the Variant Sequence in Sichuan, China. Journal Of Clinical Microbiology 1998, 36: 3378-3381. PMID: 9774600, PMCID: PMC105336, DOI: 10.1128/jcm.36.11.3378-3381.1998.Peer-Reviewed Original ResearchAllelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon.
Ferreira M, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura E, Katzin A, Isomura S, Kawamoto F. Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon. American Journal Of Tropical Medicine And Hygiene 1998, 59: 474-80. PMID: 9749647, DOI: 10.4269/ajtmh.1998.59.474.Peer-Reviewed Original ResearchConceptsMalaria-endemic areasSymptomatic malaria patientsAllelic typesMalaria patientsHypoendemic areaPolymerase chain reactionClinical isolatesP. falciparumMerozoite surface protein 1 geneGene typesPlasmodium falciparumProtein 1 geneVariable blocks 2Chain reactionPlasmodium falciparum merozoite surface protein 1 geneMerozoite surface protein-1 locusDirect sequencingContradictory dataFalciparumDistinct clonesIsolatesBlock 2Variable blocksAllelic Diversity at the Merozoite Surface Protein-1 (MSP-1) Locus in Natural Plasmodium falciparum Populations: a Brief Overview
Ferreira M, Kaneko O, Kimura M, Liu Q, Kawamoto F, Tanabe K. Allelic Diversity at the Merozoite Surface Protein-1 (MSP-1) Locus in Natural Plasmodium falciparum Populations: a Brief Overview. Memórias Do Instituto Oswaldo Cruz 1998, 93: 631-638. PMID: 9830530, DOI: 10.1590/s0074-02761998000500013.Peer-Reviewed Original ResearchConceptsMSP-1 gene typesProtein-1 locusMerozoite surface protein-1 locusNon-random associationGene typesAllelic diversityParasite populationsAllelic typesSingle-copy geneFrequency-dependent immune selectionNatural Plasmodium falciparum populationsMsp-1 locusLocal parasite populationMsp-1 allelic typesDifferent gene typesPlasmodium falciparum populationsVariable blocks 2Wild isolatesSelective pressureSouthwestern Brazilian AmazonExtensive polymorphismLociHuman hostMajor malaria vaccine candidateImmune selectionHigh prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai‐Myanmar border, as revealed by acridine orange staining and PCR‐based diagnoses
Zhou M, Liu Q, Wongsrichanalai C, Suwonkerd W, Panart K, Prajakwong S, Pensiri A, Kimura M, Matsuoka H, Ferreira M, Isomura S, Kawamoto F. High prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai‐Myanmar border, as revealed by acridine orange staining and PCR‐based diagnoses. Tropical Medicine And International Health 1998, 3: 304-312. PMID: 9623932, DOI: 10.1046/j.1365-3156.1998.00223.x.Peer-Reviewed Original ResearchConceptsP. malariae infectionP. ovale infectionsP. malariaeThai-Myanmar borderMalaria patientsMalariae infectionOvale infectionsNew variant formAcridine orange staining methodHuman malaria parasitePlasmodium malariaeHigh prevalencePlasmodium ovaleTotal prevalenceP. ovaleP. malariae isolatesAcridine orange stainingMalariaeBurmese patientsInfectionMalaria parasitesPatientsThin smearsPrevalenceMixed infectionsStable Patterns of Allelic Diversity at the Merozoite Surface Protein‐1 Locus of Plasmodium falciparum in Clinical Isolates from Southern Vietnam
Ferreira M, Liu Q, Zhou M, Kimura M, Kaneko O, Van Thien H, Isomura S, Tanabe K, Kawamoto F. Stable Patterns of Allelic Diversity at the Merozoite Surface Protein‐1 Locus of Plasmodium falciparum in Clinical Isolates from Southern Vietnam. Journal Of Eukaryotic Microbiology 1998, 45: 131-136. PMID: 9495041, DOI: 10.1111/j.1550-7408.1998.tb05080.x.Peer-Reviewed Original ResearchConceptsPlasmodium falciparumFrequency-dependent immune selectionSame endemic areaMerozoite surface protein-1 locusSymptomatic patientsParasite populationsPolymerase chain reactionArea 17Endemic areasMesoendemic areaGene typesClinical isolatesAllelic typesPatientsImmune selectionDifferent gene typesChain reactionDistinct subpopulationsFalciparumPresent studyProtein-1 locusIsolatesPopulationPrevalenceAverage number
1996
Sequence variation in the 18S rRNA gene, a target for PCR-based malaria diagnosis, in Plasmodium ovale from southern Vietnam
Kawamoto F, Miyake H, Kaneko O, Kimura M, Nguyen T, Nguyen T, Liu Q, Zhou M, Le D, Kawai S, Isomura S, Wataya Y. Sequence variation in the 18S rRNA gene, a target for PCR-based malaria diagnosis, in Plasmodium ovale from southern Vietnam. Journal Of Clinical Microbiology 1996, 34: 2287-2289. PMID: 8862600, PMCID: PMC229233, DOI: 10.1128/jcm.34.9.2287-2289.1996.Peer-Reviewed Original Research