1995
A Familial Awake Movement Disorder Mimicking Restless Legs in a Sleep Apnea Patient
Yamashiro Y, Chodirker B, Hobson D, Kryger M. A Familial Awake Movement Disorder Mimicking Restless Legs in a Sleep Apnea Patient. Sleep 1995, 18: 604-607. PMID: 8552932, DOI: 10.1093/sleep/18.7.604.Peer-Reviewed Original ResearchConceptsRestless legs syndromeMovement disordersFamilial movement disordersLegs syndromeSleep apneaNasal continuous positive airway pressureContinuous positive airway pressurePositive airway pressureObstructive sleep apneaPeriodic limb movementsSleep apnea syndromeSleep apnea patientsSleep onset insomniaSupine posturingAirway pressureObese menApnea syndromeLeg sensationsRestless legsNocturnal arousalsMean durationApnea patientsDaytime sleepinessSuccessful treatmentClinical significance
1994
The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus
Shoenut J, Kerr P, Micflikier A, Yamashiro Y, Kryger M. The Effect of Nasal CPAP on Nocturnal Reflux in Patients With Aperistaltic Esophagus. CHEST Journal 1994, 106: 738-741. PMID: 8082351, DOI: 10.1378/chest.106.3.738.Peer-Reviewed Original ResearchConceptsNocturnal refluxNasal CPAPAperistaltic esophagusLES pressureReflux eventsNasal continuous positive airway pressureContinuous positive airway pressureLower esophageal sphincter pressurePositive airway pressureEsophageal sphincter pressureGroup of patientsScleroderma esophagusScleroderma groupAirway pressureSphincter pressureSleep apneaPercentage of timeCPAPPatientsSecond nightRefluxEsophagusFirst nightAchalasiaGroupWhy Should Sleep Apnea Be Diagnosed and Treated?
Yamashiro Y, Kryger M. Why Should Sleep Apnea Be Diagnosed and Treated? Clinical Pulmonary Medicine 1994, 1: 250-259. DOI: 10.1097/00045413-199407000-00007.Peer-Reviewed Original ResearchNasal continuous positive airway pressureObstructive sleep apneaSevere sequelaeRepetitive upper airway obstructionsContinuous positive airway pressureUpper airway obstructionPositive airway pressureTreatment of choiceGoal of treatmentPrimary pathophysiologic eventEffect of treatmentAirway obstructionAirway pressureSevere complicationsPatients' qualitySleep apneaMultisystem dysfunctionPathophysiologic eventsCommon disorderUndiagnosed patientsSevere casesSequelaePatient's lifeApneaPatientsAcute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep
Yamashiro Y, Kryger M. Acute Effect of Nasal CPAP on Periodic Limb Movements Associated with Breathing Disorders During Sleep. Sleep 1994, 17: 172-175. PMID: 8036372, DOI: 10.1093/sleep/17.2.172.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressurePeriodic limb movementsSleep-disordered breathingPLMS indexAcute effectsContinuous positive airway pressureLimb movementsSplit-night protocolPositive airway pressureNCPAP treatmentNasal CPAPAirway pressureBreathing disordersBreathingTreatmentFuture investigationsApneaCPAPPatientsSleep
1993
Nasal Continuous Positive Airway Pressure
Kerr P, Shoenut J, Steens R, Millar T, Micflikier A, Kryger M. Nasal Continuous Positive Airway Pressure. Journal Of Clinical Gastroenterology 1993, 17: 276-280. PMID: 8308210, DOI: 10.1097/00004836-199312000-00002.Peer-Reviewed Original ResearchConceptsNasal continuous positive airway pressureContinuous positive airway pressureNocturnal gastroesophageal refluxLower esophageal pressurePositive airway pressureGastroesophageal refluxReflux patientsAirway pressureEsophageal pressureObstructive sleep apnea syndrome (OSAS) patientsSleep apnea syndrome patientsMean reflux durationNon-OSA patientsHealthy adult volunteersCPAP effectsNocturnal refluxEsophageal manometryMean durationIntraesophageal pressureLongest refluxSyndrome patientsHealthy volunteersReflux durationPatientsAdult volunteers
1992
MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA
Kryger M. MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA. Clinics In Chest Medicine 1992, 13: 481-492. PMID: 1521414, DOI: 10.1016/s0272-5231(21)00875-3.Peer-Reviewed Original ResearchConceptsPositive airway pressureObstructive sleep apneaAirway pressureSleep apneaNasal continuous positive airway pressureBilevel positive airway pressureContinuous positive airway pressureGeneral therapeutic measuresUpper airway abnormalitiesMinority of patientsLong-term efficacyHours of sleepHypopnea frequencyAirway abnormalitiesObese patientsSurgical managementDrug therapyTherapeutic measuresEffective treatmentPatientsSpecific abnormalitiesApneaWeight lossTreatmentAbnormalitiesNasal CPAP Reduces Gastroesophageal Reflux in Obstructive Sleep Apnea Syndrome
Kerr P, Shoenut J, Millar T, Buckle P, Kryger M. Nasal CPAP Reduces Gastroesophageal Reflux in Obstructive Sleep Apnea Syndrome. CHEST Journal 1992, 101: 1539-1544. PMID: 1600771, DOI: 10.1378/chest.101.6.1539.Peer-Reviewed Original ResearchConceptsNocturnal gastroesophageal refluxGastroesophageal refluxNasal CPAPIntrathoracic pressureNasal continuous positive airway pressureObstructive sleep apnea syndrome (OSAS) patientsContinuous positive airway pressureSleep apnea syndrome patientsObstructive sleep apnea syndromePositive airway pressureSleep apnea syndromeEsophageal pressure recordingAntireflux therapyGER frequencyAirway pressureOSAS patientsApnea syndromeClinical impressionSyndrome patientsPressure recordingsCPAPPatientsConsecutive daysNight twoMean percentage