Featured Publications
Association of Social Isolation With Disability Burden and 1-Year Mortality Among Older Adults With Critical Illness
Falvey JR, Cohen AB, O’Leary J, Leo-Summers L, Murphy TE, Ferrante LE. Association of Social Isolation With Disability Burden and 1-Year Mortality Among Older Adults With Critical Illness. JAMA Internal Medicine 2021, 181: 1433-1439. PMID: 34491282, PMCID: PMC8424527, DOI: 10.1001/jamainternmed.2021.5022.Peer-Reviewed Original ResearchConceptsCritical illnessICU hospitalizationSocial isolation scoresOlder adultsICU admissionCohort studyPrimary outcomeDisability burdenSocial isolationCommunity-dwelling older adultsGreater disability burdenIsolation scoresPost-ICU disabilityObservational cohort studyAging Trends StudyICU stayMortality cohortHospital dischargeSecondary outcomesHospital admissionMedian ageIllness severityAdverse outcomesNational HealthHospitalization dataPre–Intensive Care Unit Cognitive Status, Subsequent Disability, and New Nursing Home Admission among Critically Ill Older Adults
Ferrante LE, Murphy TE, Gahbauer EA, Leo-Summers LS, Pisani MA, Gill TM. Pre–Intensive Care Unit Cognitive Status, Subsequent Disability, and New Nursing Home Admission among Critically Ill Older Adults. Annals Of The American Thoracic Society 2018, 15: 622-629. PMID: 29446993, PMCID: PMC5949607, DOI: 10.1513/annalsats.201709-702oc.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionNew nursing home admissionsNursing home admissionCare unit admissionHome admissionCritical illnessUnit admissionModerate impairmentCognitive statusCognitive impairmentOlder adultsMinimal impairmentMultivariable analysisIntensive care unit stayMini-Mental State ExaminationProspective cohort studyIll Older AdultsModerate cognitive impairmentUnit stayCohort studySecondary outcomesSubsequent disabilityPrimary outcomeMean agePrognostic informationIn-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization
Kaushik R, McAvay G, Murphy T, Acampora D, Araujo K, Charpentier P, Chattopadhyay S, Geda M, Gill T, Kaminski T, Lee S, Li J, Cohen A, Hajduk A, Ferrante L. In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization. JAMA Network Open 2024, 7: e2419640. PMID: 38954414, PMCID: PMC11220565, DOI: 10.1001/jamanetworkopen.2024.19640.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumChart-Based Delirium Identification InstrumentOlder adultsFunctional disabilityCOVID-19 hospitalizationCognitive impairmentCohort studyAssociated with increased functional disabilityHospitalized older adultsIncreased functional disabilityAssociation of deliriumPostdischarge follow-upRisk of deliriumTertiary care systemFollow-upPresence of cognitive impairmentProspective cohort studyLogistic regression modelsOlder survivorsCare systemIncreasing cognitive impairmentMain OutcomesCOVID-19Hospital dischargePrimary outcome
2022
Association Between Daily Average of Mobility Achieved During Physical Therapy Sessions and Hospital-Acquired or Ventilator-Associated Pneumonia among Critically Ill Patients
Qi W, Murphy TE, Doyle MM, Ferrante LE. Association Between Daily Average of Mobility Achieved During Physical Therapy Sessions and Hospital-Acquired or Ventilator-Associated Pneumonia among Critically Ill Patients. Journal Of Intensive Care Medicine 2022, 38: 418-424. PMID: 36278257, PMCID: PMC10065937, DOI: 10.1177/08850666221133318.Peer-Reviewed Original ResearchConceptsVentilator-associated pneumoniaHAP/ventilator-associated pneumoniaMechanical ventilation statusPhysical therapy sessionsPhysical therapyIll patientsChronic Health Evaluation IIBaseline ambulatory statusImproved physical functionIncidence of HAPProgressive mobility programRetrospective cohort studyTherapy sessionsAcute PhysiologyAmbulatory statusCohort studyMedical ICUEarly mobilizationHospital-AcquiredPrimary outcomeDecreased riskPhysical functionEvaluation IIRisk factorsProtective associationSWEAT ICU—An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs
Agarwal A, Chen JT, Coopersmith CM, Denson JL, Dickert NW, Ferrante LE, Gershengorn HB, Gosine AD, Hayward BJ, Kaur N, Khan A, Lamberton C, Landsittel D, Lyons PG, Mikkelsen ME, Nadig NR, Pietropaoli AP, Poole BR, Viglianti EM, Sevransky JE, Network O. SWEAT ICU—An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs. Critical Care Explorations 2022, 4: e0774. PMID: 36259061, PMCID: PMC9575792, DOI: 10.1097/cce.0000000000000774.Peer-Reviewed Original ResearchPatient mortalityICU physiciansObservational studyStudy daysPhysician workloadCross-sectional observational studyMultivariable logistic regression modelAdult ICU patientsSecondary outcome measuresPhysician burnoutNumber of patientsOptimal staffing modelLogistic regression modelsMedian patientICU patientsPrimary outcomeWell-Being IndexPrimary exposurePhysician careOverall prevalencePatient outcomesAcademic ICUsOutcome measuresDay 28Binomial mixed effects models