2011
Use of Lambda-Mu-Sigma-Derived Z Score for Evaluating Respiratory Impairment in Middle-Aged Persons
Fragoso C, Gill TM, McAvay G, Van Ness PH, Yaggi HK, Concato J. Use of Lambda-Mu-Sigma-Derived Z Score for Evaluating Respiratory Impairment in Middle-Aged Persons. Respiratory Care 2011, 56: 1771-1777. PMID: 21605489, PMCID: PMC3676885, DOI: 10.4187/respcare.01192.Peer-Reviewed Original ResearchConceptsRespiratory symptomsRespiratory impairmentMiddle-aged personsZ-scoreAirflow limitationSpirometric valuesParticipants ages 45Normal age-related changesNutrition Examination SurveyThird National HealthLambda-muMiddle-age personsAge-related changesPulmonary functionExamination SurveyAtherosclerosis RiskNational HealthAge 45Spirometric dataSymptomsMortalityCommunity studyImpairmentScoresValid strategyRespiratory Impairment and Mortality in Older Persons
Fragoso C, Gill T, McAvay G, Yaggi H, Van Ness P, Concato J. Respiratory Impairment and Mortality in Older Persons. Journal Of Investigative Medicine 2011, 59: 1089. DOI: 10.2310/jim.0b013e31822bb213.Peer-Reviewed Original ResearchRespiratory symptomsRespiratory impairmentOlder personsAirflow limitationPulmonary functionRestrictive patternNHANES IIIZ-scoreSpirometric Z-scoresCardiovascular Health StudyRisk of deathNutrition Examination SurveyThird National HealthAge-related changesCause mortalityHazard ratioMultivariable analysisExamination SurveyNational HealthOdds ratioSpirometric measuresOutcome dataHealth StudyCHS populationFifth percentile
2009
The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease
Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM. The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2009, 181: 446-451. PMID: 20019341, PMCID: PMC3159085, DOI: 10.1164/rccm.200909-1366oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseFEV1/FVCObstructive pulmonary diseaseRisk of deathRespiratory symptomsPulmonary diseaseAdjusted hazard ratioRatio of FEV1Hazard ratioOdds ratioFVCClinical validityFifth percentileZ-scoreIdentifies personsSymptomsWhite personsDiseaseMeaningful outcomesDeathLambda-muPrevalenceRiskRepresentative sampleHigh threshold