Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia.
Corl K, Zeba F, Caffrey A, Hermenau M, Lopes V, Phillips G, Merchant R, Levy M, LaPlante K. Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia. Critical Care Medicine 2020, 48: 525-532. PMID: 32205599, DOI: 10.1097/ccm.0000000000004212.Peer-Reviewed Original ResearchConceptsS. aureus bacteremiaStaphylococcus aureus bacteremiaSeptic shock patientsSeptic shockAntibiotic administrationShock patientsMethicillin-sensitive S. aureus bacteremiaMethicillin-resistant S. aureusThirty-day mortalityTiming of antibioticsAssociated with mortalityVeterans Affairs Health SystemThirty-dayRetrospective analysisBacteremiaEmergency department presentationsMultivariate analysisOdds ratioPatientsEmergency departmentAntibioticsMortalityAdministrationOddsHealth systemAssociation of prescription opioid use on mortality and hospital length of stay in the intensive care unit
Hardy N, Zeba F, Ovalle A, Yanac A, Nzugang-Noutonsi C, Abadier M, Ovalle A, Chahin A. Association of prescription opioid use on mortality and hospital length of stay in the intensive care unit. PLOS ONE 2021, 16: e0250320. PMID: 33886667, PMCID: PMC8061930, DOI: 10.1371/journal.pone.0250320.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAnalgesics, OpioidCase-Control StudiesCritical CareElectronic Health RecordsFemaleHospital MortalityHumansIntensive Care UnitsLength of StayLongitudinal StudiesMaleMiddle AgedOpioid-Related DisordersPatient ReadmissionRetrospective StudiesRisk FactorsUnited StatesConceptsPrescription opioid useIntensive care unitIntensive care unit admissionAssociation of prescription opioid useOpioid usePrescribed opioidsPatients prescribed chronic opioidsAccurate medication reconciliationRisk of hospital readmissionIncreased risk of hospital readmissionLongitudinal retrospective cohort studyAcademic medical centerCare unitCritical care settingHospital lengthAssociated with increased hospital lengthMedication reconciliationHospital stayTertiary-care academic medical centerCare settingsHospital length of stayRetrospective cohort studyAssociated with increased mortalityLength of stayNon-prescription opioid use