2010
Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate
Wisnewski AV, Liu J, Redlich CA. Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate. Analytical Biochemistry 2010, 400: 251-258. PMID: 20123080, PMCID: PMC3106273, DOI: 10.1016/j.ab.2010.01.037.Peer-Reviewed Original ResearchConceptsHigh-performance liquid chromatographyDiphenylmethane diisocyanateConjugation sitesReaction productsCross-linking agentTandem mass spectrometryPolyurethane productionMass spectrometryMDI-exposed workersCause of asthmaHuman albuminSerum immunoglobulin GLiquid chromatographyReaction specificityDiisocyanateSecond lysineMDI conjugationAirway inflammationAnalytical methodSelf proteinsProteomic methodologiesEpitope specificityAntigenic changesClinical researchConjugates
2003
Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate
Wisnewski AV, Herrick CA, Liu Q, Chen L, Bottomly K, Redlich CA. Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate. Journal Of Allergy And Clinical Immunology 2003, 112: 538-546. PMID: 13679813, DOI: 10.1016/s0091-6749(03)01865-7.Peer-Reviewed Original ResearchConceptsGamma/delta T cellsDelta T cellsHuman immune responseT cellsT cell receptorImmune responseAlpha/beta T cell receptorBeta T cell receptorHuman airway epithelial cellsIFN-γ productionGamma/deltaT cell proliferationAirway epithelial cellsHuman T cell lineT cell linesHuman T cellsCell typesOccupational asthmaCytokine productionPeripheral bloodIL-13IL-5Antigen-mediated selectionAntigen leadIFN-gamma
1990
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction.
Omiecinski C, Redlich C, Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. Cancer Research 1990, 50: 4315-21. PMID: 1694720.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsBase SequenceBlotting, NorthernBlotting, SouthernCytochrome P-450 Enzyme SystemDNAGene Expression Regulation, EnzymologicGenesIsoenzymesLiverMethylcholanthreneMolecular Sequence DataOligonucleotide ProbesOrgan SpecificityPhenobarbitalPolymerase Chain ReactionRatsRats, Inbred StrainsReference ValuesRNARNA, MessengerConceptsPolymerase chain reactionHuman pulmonary alveolar macrophagesChain reactionP450IA1 mRNAEarly gestational stageEnvironmental chemical exposuresPulmonary alveolar macrophagesDevelopmental ageTransplacental treatmentFetal ratsHuman gestationGestational stagesRat lungAlveolar macrophagesDay 15Related cancersHuman tissue samplesIndividual susceptibilityDay 45Fetal liver developmentTarget cellsMRNA expression patternsRatsTissue samplesChemical exposure