2024
Development and evaluation of a questionnaire to capture environmental and occupational inhalational exposures in adults with fibrotic interstitial lung disease
Swaminathan A, McFatrich M, Mkumba L, Wright L, Redlich C, Snyder L, Reeve B, Patel D, Gulati M. Development and evaluation of a questionnaire to capture environmental and occupational inhalational exposures in adults with fibrotic interstitial lung disease. Respiratory Research 2024, 25: 372. PMID: 39407223, PMCID: PMC11481565, DOI: 10.1186/s12931-024-03000-z.Peer-Reviewed Original ResearchConceptsCognitive interviewsContent validityExposure questionnaireMultidisciplinary teamSemi-structured interview guideEvidence of content validityFibrosing ILDsInterstitial lung diseaseRelevant exposuresFibrotic interstitial lung diseaseClinically relevant exposuresTrained interviewersInterview guideAssessment QuestionnaireQuestionnaireInterviewsLung diseaseAdultsTeamClinicPatientsSource of misunderstandingOccupational inhalation exposureValidityDisease
2021
Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel
Zell J, Wisnewski AV, Liu J, Klein J, Lucas C, Slade M, Iwasaki A, Redlich CA. Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel. PLOS ONE 2021, 16: e0251114. PMID: 34460832, PMCID: PMC8405017, DOI: 10.1371/journal.pone.0251114.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Live SARS-CoV-2Moderate SARS-CoV-2SARS-CoV-2 seroprevalenceWork-related risk factorsTransportation-related occupationsSerum IgG levelsAntigen-specific IgGIgG seropositivity rateBiomarkers of infectionSARS-CoV-2 spikeCOVID-19 exposureUS National Guard soldiersMilitary personnelIgG levelsSeropositivity rateHumoral responseSerum IgGViral exposureBlack raceRisk factorsOdds ratioStudy populationNational Guard soldiersDemographic data
2019
The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement
Blanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Torén K, Vinnikov D, Redlich CA. The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement. American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1312-1334. PMID: 31149852, PMCID: PMC6543721, DOI: 10.1164/rccm.201904-0717st.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNonmalignant respiratory diseasesChronic obstructive pulmonary diseaseObstructive pulmonary diseasePopulation attributable fractionChronic respiratory diseasesRespiratory diseaseWorkplace exposuresPulmonary diseaseHypersensitivity pneumonitisAttributable fractionOccupational burdenOfficial American Thoracic SocietyEuropean Respiratory Society statementCommunity-acquired pneumoniaGranulomatous lung diseaseIdiopathic pulmonary fibrosisPopulation-based studyIncidence rate ratiosPulmonary alveolar proteinosisBurden of diseaseAmerican Thoracic SocietyWorking-age adultsPublic health awarenessAirway diseaseChronic bronchitisRates and occupational characteristics of international seafarers with mental illness
Lefkowitz R, Slade M, Redlich C. Rates and occupational characteristics of international seafarers with mental illness. Occupational Medicine 2019, 69: 279-282. PMID: 31094424, DOI: 10.1093/occmed/kqz069.Peer-Reviewed Original ResearchConceptsMental illnessIncidence ratePossible excess riskIllness incidence ratesMental illness ratesSeafarer populationExcess riskIllness ratesMedical careIllnessInternational seafarersOccupational conditionsIllness claimsOccupational characteristicsSocial supportClaim ratesDescriptive statisticsInsurance providersStudy dataObjective dataHigh thresholdLarge populationPopulationCareYears 2007
2017
Injury, illness, and disability risk in American seafarers
Lefkowitz RY, Slade MD, Redlich CA. Injury, illness, and disability risk in American seafarers. American Journal Of Industrial Medicine 2017, 61: 120-129. PMID: 29250811, DOI: 10.1002/ajim.22802.Peer-Reviewed Original ResearchMeSH KeywordsAdultDatabases, FactualFemaleGastrointestinal DiseasesHumansLogistic ModelsMaleMiddle AgedNaval MedicineOccupational DiseasesOccupational InjuriesOdds RatioRespiratory Tract DiseasesRetrospective StudiesRiskShipsSkin DiseasesStomatognathic DiseasesTelemedicineTransportationUnited StatesConceptsDisability riskHigher disability riskOverall injury rateLogistic regression modelingResultant disabilityRisk factorsHigh riskIllness incidenceInjury ratesPreventive interventionsMedical careIllness ratesInjuryTelemedicine databaseIllnessRegression modelingEssential workforceDescriptive statistical methodsRiskAdditional researchDisabilityIncidenceCareMedical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States
Cassidy LD, Doney B, Wang ML, Kurth L, Conner PR, Collins JJ, Carson M, Molenaar D, Redlich CA, Storey E. Medical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States. Journal Of Occupational And Environmental Medicine 2017, 59: s13-s21. PMID: 29200134, PMCID: PMC5728423, DOI: 10.1097/jom.0000000000001197.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAsthma, OccupationalChemical IndustryEnvironmental MonitoringFemaleForced Expiratory VolumeHumansMaleMiddle AgedOccupational ExposurePopulation SurveillanceProgram EvaluationReferral and ConsultationSpirometrySurveys and QuestionnairesSymptom AssessmentToluene 2,4-DiisocyanateUnited StatesYoung AdultConceptsLung function criteriaOccupational health programWeb-based data collection systemTDI workersOccupational asthmaPossible asthmaStudy protocolHealth outcomesMultidisciplinary teamHealth programsMedical monitoringAsthmaFurther evaluationEligible workersFurther assessmentResearch protocolPotential casesSubsequent evaluationProduction workersSymptomsToluene diisocyanateWorkersEvaluationIncidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry
Collins JJ, Anteau S, Conner PR, Cassidy LD, Doney B, Wang ML, Kurth L, Carson M, Molenaar D, Redlich CA, Storey E. Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry. Journal Of Occupational And Environmental Medicine 2017, 59: s22-s27. PMID: 29200135, PMCID: PMC5763544, DOI: 10.1097/jom.0000000000000890.Peer-Reviewed Original ResearchThe Limits of Pattern Recognition: Nodular Lung Disease in a Syrian Refugee
Lefkowitz RY, Mitma AA, Altassan K, Redlich CA. The Limits of Pattern Recognition: Nodular Lung Disease in a Syrian Refugee. Annals Of The American Thoracic Society 2017, 14: 1591-1594. PMID: 28961033, DOI: 10.1513/annalsats.201702-163cc.Peer-Reviewed Case Reports and Technical Notes
2016
Patterns of Energy Drink Use and Associated Symptoms Among a Population of Connecticut Factory Workers
Pensa MA, Galusha DH, Stowe MH, Lefkowitz RY, Redlich CA. Patterns of Energy Drink Use and Associated Symptoms Among a Population of Connecticut Factory Workers. Journal Of Occupational And Environmental Medicine 2016, 58: e188-e190. PMID: 27158968, DOI: 10.1097/jom.0000000000000728.Peer-Reviewed Original Research
2015
Elevated Blood Lead Levels Related to the Use of Firearms
Cook JM, Sakr CJ, Redlich CA, DeLoreto AL. Elevated Blood Lead Levels Related to the Use of Firearms. Journal Of Occupational And Environmental Medicine 2015, 57: e136-e138. PMID: 26461876, DOI: 10.1097/jom.0000000000000553.Peer-Reviewed Case Reports and Technical NotesRisk factors for merchant seafarer repatriation due to injury or illness at sea
Lefkowitz RY, Slade MD, Redlich CA. Risk factors for merchant seafarer repatriation due to injury or illness at sea. International Maritime Health 2015, 66: 61-66. PMID: 26119673, DOI: 10.5603/imh.2015.0016.Peer-Reviewed Original ResearchConceptsRisk factorsLogistic regressionModifiable risk factorsSignificant risk factorsFrequent causeGastrointestinal illnessSerious outcomesIllness casesBack injuriesInjuryIllnessSeafarer injuryTelemedicine databaseMajor causeStudy periodDescriptive statisticsYear periodFuture studiesCauseFactorsRegressionCohortStudy“Injury, illness, and work restriction in merchant seafarers”
Lefkowitz RY, Slade MD, Redlich CA. “Injury, illness, and work restriction in merchant seafarers”. American Journal Of Industrial Medicine 2015, 58: 688-696. PMID: 25939921, DOI: 10.1002/ajim.22459.Peer-Reviewed Original Research
2014
Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: Initial one‐year follow‐up
Gui W, Wisnewski AV, Neamtiu I, Gurzau E, Sparer JA, Stowe MH, Liu J, Slade MD, Rusu OA, Redlich CA. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: Initial one‐year follow‐up. American Journal Of Industrial Medicine 2014, 57: 1207-1215. PMID: 25266741, PMCID: PMC4198484, DOI: 10.1002/ajim.22385.Peer-Reviewed Original ResearchMeSH KeywordsAdultAir Pollutants, OccupationalAirway ObstructionAsthma, OccupationalFemaleFollow-Up StudiesForced Expiratory VolumeHumansImmunoglobulin EImmunoglobulin GLost to Follow-UpMaleMiddle AgedOccupational ExposurePolyurethanesPrevalenceProspective StudiesTime FactorsToluene 2,4-DiisocyanateVital CapacityYoung AdultConceptsAsthma symptomsIsocyanate asthmaInception cohort studyHealth effectsCurrent asthma symptomsTDI levelsFirst yearFurther longitudinal evaluationAirflow obstructionCohort studyInception cohortOccupational asthmaTDI exposureRespiratory healthSkin exposureLongitudinal evaluationAsthmaOne-yearPersonal samplingSymptomsRiskExposureFindingsFEV1Spirometry
2013
Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure
Wisnewski AV, Liu J, Redlich CA. Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure. Chemico-Biological Interactions 2013, 205: 38-45. PMID: 23791970, PMCID: PMC3767171, DOI: 10.1016/j.cbi.2013.06.005.Peer-Reviewed Original Research
2012
Skin and respiratory symptoms among workers with suspected work-related disease
Arrandale V, Kudla I, Kraut A, Scott J, Tarlo S, Redlich C, Holness D. Skin and respiratory symptoms among workers with suspected work-related disease. Occupational Medicine 2012, 62: 420-426. PMID: 22915563, DOI: 10.1093/occmed/kqs133.Peer-Reviewed Original ResearchConceptsWork-related skinHistory of eczemaRespiratory symptomsConcurrent skinSkin outcomesRespiratory diseaseWork-related skin diseaseMultiple logistic regression modelInterviewer-administered questionnaireWork-related respiratory diseaseImpaired barrier functionWork-related diseasesLogistic regression modelsCurrent smokingSmoking habitsMean ageOccupational exposureRespirator useGreater oddsSkin diseasesHealth historySymptomsMost subjectsBarrier functionDiseaseBiomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG
Wisnewski AV, Stowe MH, Nerlinger A, Opare-addo P, Decamp D, Kleinsmith CR, Redlich CA. Biomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG. Annals Of Work Exposures And Health 2012, 56: 901-910. PMID: 22449630, PMCID: PMC3471419, DOI: 10.1093/annhyg/mes024.Peer-Reviewed Original ResearchConceptsPersonal protective equipmentSkin exposureExposure surveillanceSpecific serum immunoglobulin GHexamethylene diisocyanate exposureSerum IgG levelsSerum immunoglobulin GNight shift workEnzyme-linked immunosorbentAdverse health effectsAsthma historyDiisocyanate exposureIgG levelsSerum levelsIgG titersChemical allergensPPE useImmune responseRespirator useIsocyanate exposureExposure biomarkersPractical biomarkersBasic demographicsHigh titersHygiene effortsSkin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms
Arrandale V, Meijster T, Pronk A, Doekes G, Redlich CA, Holness DL, Heederik D. Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms. International Archives Of Occupational And Environmental Health 2012, 86: 167-175. PMID: 22411214, PMCID: PMC3555349, DOI: 10.1007/s00420-012-0760-x.Peer-Reviewed Original ResearchConceptsAuto body shop workersExposure-response relationshipRespiratory symptomsSkin symptomsItchy skinShop workersBakery workersPossible exposure-response relationshipSignificant exposure-response associationsExposure-response associationsRespiratory outcomesMean ageDry skinSkin exposureSymptomsAverage exposureStatistical significanceWheat allergensSkinExposureAssociationPrevious studiesResultsDataMethodsDataWorkers
2011
An Official American Thoracic Society Statement: Work-Exacerbated Asthma
Henneberger PK, Redlich CA, Callahan DB, Harber P, Lemière C, Martin J, Tarlo SM, Vandenplas O, Torén K. An Official American Thoracic Society Statement: Work-Exacerbated Asthma. American Journal Of Respiratory And Critical Care Medicine 2011, 184: 368-378. PMID: 21804122, DOI: 10.1164/rccm.812011st.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsWork-exacerbated asthmaWork-related symptomsClinical characteristicsOccupational asthmaOfficial American Thoracic Society StatementAmerican Thoracic Society StatementWorsening of asthmaOnset of asthmaStandard medical managementMedical managementAdverse outcomesDescriptive epidemiologyOA casesRisk factorsAdverse socioeconomic outcomesCase definitionOccupational exposureSociety statementMedian prevalenceAsthmaWork exposurePreventive interventionsMedical careMedical literatureSystematic search
2007
Cost‐Effectiveness of Various Diagnostic Approaches for Occupational Asthma
Kennedy WA, Girard F, Chaboillez S, Cartier A, Côté J, Hargreave F, Labrecque M, Malo JL, Tarlo SM, Redlich CA, Lemière C. Cost‐Effectiveness of Various Diagnostic Approaches for Occupational Asthma. Canadian Respiratory Journal 2007, 14: 276-280. PMID: 17703242, PMCID: PMC2676393, DOI: 10.1155/2007/206519.Peer-Reviewed Original ResearchConceptsSpecific inhalation challengeOccupational asthmaSputum testingProbabilistic sensitivity analysesPEF monitoringDiagnosis of OASputum cell countsProportion of eosinophilsExpiratory flow monitoringAdditional correct diagnosisBase-case analysisInhalation challengeClinical outcomesOA patientsTreeAge ProClinical dataSerial measurementsCorrect diagnosisPatientsCanadian hospitalsCell countDiagnostic approachGold standardDiagnosisCost-effective alternative
2006
Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma
Ye YM, Kim CW, Kim HR, Kim HM, Suh CH, Nahm DH, Park HS, Redlich CA, Wisnewski AV. Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma. Journal Of Allergy And Clinical Immunology 2006, 118: 885-891. PMID: 17030242, DOI: 10.1016/j.jaci.2006.06.026.Peer-Reviewed Original Research