2012
Transferability of Aliphatic Isocyanates from Recently Applied Paints to the Skin of Auto Body Shop Workers
De Vries TT, Bello D, Stowe MH, Harari H, Slade MD, Redlich CA. Transferability of Aliphatic Isocyanates from Recently Applied Paints to the Skin of Auto Body Shop Workers. Journal Of Occupational And Environmental Hygiene 2012, 9: 699-711. PMID: 23067057, DOI: 10.1080/15459624.2012.728893.Peer-Reviewed Original ResearchConceptsSkin exposureSkin samplesAuto body shop workersOccupational asthmaIsocyanate asthmaCommon causeSkin wipesGreater riskSkin contactPotent sensitizerInitial sampling timeShop workersPositive samplesAsthmaAuto body shopsHigh-performance liquid chromatographyExposureCross-linking chemicalsRiskGeometric meanLiquid chromatography
2010
Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate
Wisnewski AV, Liu J, Redlich CA. Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate. Analytical Biochemistry 2010, 400: 251-258. PMID: 20123080, PMCID: PMC3106273, DOI: 10.1016/j.ab.2010.01.037.Peer-Reviewed Original ResearchConceptsHigh-performance liquid chromatographyDiphenylmethane diisocyanateConjugation sitesReaction productsCross-linking agentTandem mass spectrometryPolyurethane productionMass spectrometryMDI-exposed workersCause of asthmaHuman albuminSerum immunoglobulin GLiquid chromatographyReaction specificityDiisocyanateSecond lysineMDI conjugationAirway inflammationAnalytical methodSelf proteinsProteomic methodologiesEpitope specificityAntigenic changesClinical researchConjugates