2022
Blue light potentiates safety and bactericidal activity of p-Toluquinone
Wang S, Wong K, Li Y, Ishii M, Li X, Wei L, Lu M, Wu M. Blue light potentiates safety and bactericidal activity of p-Toluquinone. Journal Of Photochemistry And Photobiology B Biology 2022, 230: 112427. PMID: 35338920, DOI: 10.1016/j.jphotobiol.2022.112427.Peer-Reviewed Original ResearchConceptsMultiple drug resistanceBacterial infectionsBactericidal activityE. coli infectionHospital-acquired infectionsMDR bacterial infectionsMDR Escherichia coliNon-specific natureColi infectionCombinatory therapyOxygen species generationInfectionScratch woundBrief exposureEnterococcus faecalisSpecies generationKilling efficacyOpposite effectRecurrenceTherapy
2021
Bacteria-specific phototoxic reactions triggered by blue light and phytochemical carvacrol
Lu M, Wang S, Wang T, Hu S, Bhayana B, Ishii M, Kong Y, Cai Y, Dai T, Cui W, Wu M. Bacteria-specific phototoxic reactions triggered by blue light and phytochemical carvacrol. Science Translational Medicine 2021, 13 PMID: 33408183, DOI: 10.1126/scitranslmed.aba3571.Peer-Reviewed Original ResearchConceptsPhototoxic reactionsMammalian cellsMultidrug-resistant bacterial infectionsSkin wound infectionThird-degree burn woundsAdverse eventsBacterial colony-forming unitsWound infectionCombined therapyAntibiotic susceptibilityMDR bacteriaBacterial infectionsBurn woundsSingle treatmentColony-forming unitsBlue lightArray of bacteriaInfectionWound healingHost DNABacterial resistanceMature biofilmsOxygen speciesSuccessive passagesTreatment