The Long History of Long COVID and Other Chronic Illnesses
The term post-acute infection syndrome refers to chronic diseases that occur after an acute viral, bacterial, or parasitic infection, including chronic Lyme and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Yale School of Medicine is investigating the many questions surrounding post-acute infection syndromes in its new Center for Infection & Immunity.
Fierce 50 Breakthroughs
When the 2018 Nobel Prize in Physiology or Medicine recognized discoveries in cancer immune checkpoints, one name was notably missing from the winners: Lieping Chen, Ph.D., from Yale University. Chen’s lab at Mayo Clinic then first identified B7-H1, which was later renamed PD-L1. In 2002, Chen’s team was the first to report the PD-1/L1 axis as an immune evasion mechanism for cancer cells. “These findings have implications for the design of T cell-based cancer immunotherapy,” Chen and colleagues wrote presciently in their 2002 Nature Medicine article.Source: Fierce
Researchers Develop Algorithm To Predict Whether A Person Gets Long Covid
Researchers with Mount Sinai Hospital and Yale University say they’re the first to identify specific blood biomarkers that can accurately identify long Covid—allowing them to create an algorithm to determine whether a patient is suffering from the lingering condition, according to a new study published Monday in the journal Nature.Source: Forbes
A Human Protein Found in Non-Immune Cells Defends Against COVID-19
Scientists have found that cells that line human lungs and other tissues express a protein that can halt SARS-CoV-2 replication before the virus spreads to nearby cells. Their discovery could one day point to new therapeutic strategies to treat or prevent COVID-19, particularly for individuals who are more vulnerable to severe infection.Source: HHMI
Yale researchers are working on a whole new type of vaccine, targeting the insects that carry pathogens
A group of Yale researchers is working on a new kind of vaccine they believe could change the world: instead of acting against a pathogen, the vaccine would reduce the risk of transmission for mosquito-and-tick-borne illnesses by targeting the insects themselves.Source: Stamford Advocate
Blavatnik Fund for Innovation at Yale Awards $2.5 Million to 11 Faculty-Led Projects
The Blavatnik Fund for Innovation at Yale, made possible by a generous grant from the Blavatnik Family Foundation, supports Yale faculty in the commercialization of biomedical and digital health innovations.Source: Yale Ventures
Akiko Iwasaki to Receive the 2023 Connecticut Medal of Science
Akiko Iwasaki, Sterling Professor of Immunobiology and Professor of Dermatology and of Molecular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases), Yale School of Medicine, and an Investigator for the Howard Hughes Medical Institute, has been selected as the 2023 recipient of the Connecticut Medal of Science. Dr. Iwasaki is recognized for her major discoveries in the areas of innate sensing of viruses, and instruction of adaptive anti-viral immunity.Source: Connecticut Academy of Science and Engineering
Iwasaki to Receive Else Kröner Fresenius Prize Supporting Research Into Long COVID and Similar Conditions
Akiko Iwasaki, PhD, Sterling Professor of Immunobiology and of Molecular, Cellular & Developmental Biology at Yale School of Medicine, has been selected to receive the 2023 Else Kröner Fresenius Prize for Medical Research, one of the most prestigious honors of its kind.