1998
Intracellular formation and cell surface expression of a complex of an intact lysosomal protein and MHC class II molecules.
Arunachalam B, Pan M, Cresswell P. Intracellular formation and cell surface expression of a complex of an intact lysosomal protein and MHC class II molecules. The Journal Of Immunology 1998, 160: 5797-806. PMID: 9637490, DOI: 10.4049/jimmunol.160.12.5797.Peer-Reviewed Original ResearchAllelesAnimalsCell Transformation, ViralElectrophoresis, Polyacrylamide GelFlow CytometryFluorescent Antibody Technique, IndirectHerpesvirus 4, HumanHistocompatibility Antigens Class IIHLA-D AntigensHLA-DR AntigensLysosomesMiceOxidoreductasesOxidoreductases Acting on Sulfur Group DonorsProteinsRabbitsSodium Dodecyl SulfateSurface Properties
1992
HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
Riberdy J, Newcomb J, Surman M, Barbosat J, Cresswell P. HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 1992, 360: 474-477. PMID: 1448172, DOI: 10.1038/360474a0.Peer-Reviewed Original ResearchConceptsClass II moleculesInvariant chainMajor histocompatibility complex (MHC) class II moleculesCell linesHLA-DR moleculesClass II binding siteInvariant chain peptideHLA-DR3 moleculesMore MHCClass IIAntigen processingT2 transfectantsAntigenic peptidesHuman cell linesChain peptideVivo conditionsPeptidesLarge proportionProteolytic cleavageMutant cell linesCertain human cell linesEarly stagesTransfectantsPresentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer
Spies T, Cerundolo V, Colonna M, Cresswell P, Townsend A, DeMars R. Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer. Nature 1992, 355: 644-646. PMID: 1538752, DOI: 10.1038/355644a0.Peer-Reviewed Original Research
1990
Isolation and characterization of a galactose-specific carbohydrate binding protein from human lymphoblastic cells
Baum L, Cresswell P. Isolation and characterization of a galactose-specific carbohydrate binding protein from human lymphoblastic cells. Biochemical And Biophysical Research Communications 1990, 173: 1079-1085. PMID: 2268313, DOI: 10.1016/s0006-291x(05)80896-4.Peer-Reviewed Original ResearchB-LymphocytesCarrier ProteinsCell LineDetergentsElectrophoresis, Polyacrylamide GelGalactosidesGalectinsHemagglutininsHumansIsoelectric FocusingMolecular WeightT-Lymphocytes
1984
Analysis of monoclonal antibodies reactive with human class II beta chains by two-dimensional electrophoresis and western blotting
Radka S, Machamer C, Cresswell P. Analysis of monoclonal antibodies reactive with human class II beta chains by two-dimensional electrophoresis and western blotting. Human Immunology 1984, 10: 177-188. PMID: 6611328, DOI: 10.1016/0198-8859(84)90038-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntigen-Antibody ComplexB-LymphocytesElectrophoresis, Polyacrylamide GelHistocompatibility Antigens Class IIHLA AntigensHumansMacromolecular SubstancesMiceMice, Inbred BALB CRatsConceptsMonomorphic monoclonal antibodiesClass II moleculesMonoclonal antibodiesBeta chainClass II beta chainPolymorphic monoclonal antibodiesHLA-DR5HLA-DRMonomorphic determinantsBeta subunitDeterminant absentPolymorphic antibodiesWestern blottingAntibodiesAntigen subunitsTwo-dimensional gel electrophoresisTwo-dimensional electrophoresisDR3
1981
A human leukocyte antigen identified by a monoclonal antibody
Berger A, Davis J, Cresswell P. A human leukocyte antigen identified by a monoclonal antibody. Human Immunology 1981, 3: 231-245. PMID: 6975769, DOI: 10.1016/0198-8859(81)90020-3.Peer-Reviewed Original ResearchConceptsLeukocyte antigenT cell linesB cell linesB lymphocytesCell linesMonoclonal antibodiesHuman leukocyte antigenPeripheral blood cellsBone marrow cellsAllogeneic cellsT cellsB cellsErythroid seriesMore antigensAntigenHuman leukocytesMarrow cellsBlood cellsNegative populationAntibodiesLymphocytesApproximate molecular weightCellsElectrophoretic mobilityMonocytes
1975
Purification of papain-solubilized histocompatibility antigens from a cultured human lymphoblastoid line, RPMI 4265.
Turner M, Cresswell P, Parham P, Strominger J, Mann D, Sanderson A. Purification of papain-solubilized histocompatibility antigens from a cultured human lymphoblastoid line, RPMI 4265. Journal Of Biological Chemistry 1975, 250: 4512-4519. PMID: 1141219, DOI: 10.1016/s0021-9258(19)41332-x.Peer-Reviewed Original ResearchConceptsSodium dodecyl sulfate gel electrophoresisSephadex GDodecyl sulfate gel electrophoresisSulfate gel electrophoresisDiethylaminoethylcellulose columnSingle bandCharge heterogeneityM ureaPreparationDEAE-cellulose columnChromatographyM KClSeparationGel electrophoresisMultiple bandsColumnSialic acid
1973
THE SMALL SUBUNIT OF HL-A ANTIGENS IS ß2-MICROGLOBULIN
Grey H, Kubo R, Colon S, Poulik M, Cresswell P, Springer T, Turner M, Strominger J. THE SMALL SUBUNIT OF HL-A ANTIGENS IS ß2-MICROGLOBULIN. Journal Of Experimental Medicine 1973, 138: 1608-1612. PMID: 4128442, PMCID: PMC2139471, DOI: 10.1084/jem.138.6.1608.Peer-Reviewed Original ResearchPapain-Solubilized HL-A Antigens from Cultured Human Lymphocytes Contain Two Peptide Fragments
Cresswell P, Turner M, Strominger J. Papain-Solubilized HL-A Antigens from Cultured Human Lymphocytes Contain Two Peptide Fragments. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 1603-1607. PMID: 4514327, PMCID: PMC433551, DOI: 10.1073/pnas.70.5.1603.Peer-Reviewed Original ResearchMeSH KeywordsAntigen-Antibody ComplexBuffersCells, CulturedCentrifugation, Density GradientChromatography, GelElectrophoresis, Polyacrylamide GelGlucosamineGlycopeptidesHistocompatibility AntigensHumansIsotope LabelingLymphocytesMannoseMolecular WeightPapainPeptidesSodium Dodecyl SulfateSolubilityTritium