Induction of Mouse Embryonal Carcinoma Cell Differentiation and Activation of the Retinoic Acid Receptor β2 Promoter by 1,25-Dihydroxyvitamin D3
Müschen M, Sies H, Schulz W. Induction of Mouse Embryonal Carcinoma Cell Differentiation and Activation of the Retinoic Acid Receptor β2 Promoter by 1,25-Dihydroxyvitamin D3. Biological Chemistry 1996, 377: 703-710. PMID: 8960371, DOI: 10.1515/bchm3.1996.377.11.703.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, NorthernBucladesineCalcitriolCarcinoma, EmbryonalCell DifferentiationCollagenCyclic AMP Response Element-Binding ProteinMicePromoter Regions, GeneticProtein Kinase CReceptors, Retinoic AcidStaurosporineTumor Cells, CulturedConceptsRAR beta 2 promoterDihydroxyvitamin D3Carcinoma cellsRetinoic acidEffects of calcitriolDb-cAMPRetinoic Acid Receptor β2 PromoterEmbryonal carcinoma cellsCalcitriolRAR betaProtein kinase C. ThereforeInduces differentiationCalcitriol-induced differentiationReporter cell lineMouse embryonal carcinoma cellsDibutyryl cAMPCell linesProtein kinase CCollagen IVEmbryonal carcinoma cell differentiationCarcinoma cell differentiationFunctional TREsBeta-galactosidase activityActivationD3