2009
Inflammatory Regulation by TLR3 in Acute Hepatitis
Xiao X, Zhao P, Rodriguez-Pinto D, Qi D, Henegariu O, Alexopoulou L, Flavell RA, Wong FS, Wen L. Inflammatory Regulation by TLR3 in Acute Hepatitis. The Journal Of Immunology 2009, 183: 3712-3719. PMID: 19710451, PMCID: PMC3787866, DOI: 10.4049/jimmunol.0901221.Peer-Reviewed Original ResearchConceptsAcute hepatitisCon ATLR3 expressionLiver damageAdaptive T cell immune responseBone marrow chimeric miceT cell immune responsesCon A injectionFunction of TLR3Hematopoietic cellsLiver mononuclear cellsCell immune responsesDamaged liver tissueWild-type miceWT hematopoietic cellsA injectionWT miceMononuclear cellsInnate activationHepatocyte damageImmune responseInflammatory regulationHepatitisMouse modelTLR3
1992
89 IMMUNOHISTOCHEMICAL ANALYSIS OF THE T-CELL RECEPTOR (TCR) USAGE BY T LYMPHOCYTES INFILTRATING THE LIVER IN AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (ACAH) AND PRIMARY SCLEROSING CHOLANGITIS (PSC)
Mustafa A, Wen L, Hussain M, Davies E, G M. 89 IMMUNOHISTOCHEMICAL ANALYSIS OF THE T-CELL RECEPTOR (TCR) USAGE BY T LYMPHOCYTES INFILTRATING THE LIVER IN AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (ACAH) AND PRIMARY SCLEROSING CHOLANGITIS (PSC). Journal Of Pediatric Gastroenterology And Nutrition 1992, 15: 355. DOI: 10.1097/00005176-199210000-00112.Peer-Reviewed Original Research
1991
γδ† T CLONES FROM LIVER BIOPSIES OF CHILDREN WITH AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (aCAH) AND PRIMARY SCLEROSING CHOLANGITIS (aPSC) ARE CYTOTOXIC TO HUMAN LIVER TARGET CELLS
Wen L, Peakman M, Mowat A, Mieli-Vergani G, Vergani D. γδ† T CLONES FROM LIVER BIOPSIES OF CHILDREN WITH AUTOIMMUNE CHRONIC ACTIVE HEPATITIS (aCAH) AND PRIMARY SCLEROSING CHOLANGITIS (aPSC) ARE CYTOTOXIC TO HUMAN LIVER TARGET CELLS. Journal Of Pediatric Gastroenterology And Nutrition 1991, 13: 323. DOI: 10.1097/00005176-199110000-00056.Peer-Reviewed Original Research
1990
T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis
Wen L, Peakman M, Lobo-Yeo A, Vergani D, Mowat A, Mieli-Vergani, McFarlane B. T-cell-directed hepatocyte damage in autoimmune chronic active hepatitis. The Lancet 1990, 336: 1527-1530. PMID: 1979365, DOI: 10.1016/0140-6736(90)93306-a.Peer-Reviewed Original ResearchConceptsAutoimmune chronic active hepatitisChronic active hepatitisActive hepatitisPeripheral bloodT lymphocytesAutologous B lymphocytesLiver membrane antigensT cell clonesAsialoglycoprotein receptorActivated T lymphocytesLiver cell membraneSpecific autoantibodiesAutoimmune attackImmune attackHepatocyte damageHepatitisB lymphocytesLymphocytesBloodLipoprotein complexAutoantibodiesPatientsCell membraneAntigenClones