1996
Murine lupus in the absence of alpha beta T cells.
Peng SL, Madaio MP, Hughes DP, Crispe IN, Owen MJ, Wen L, Hayday AC, Craft J. Murine lupus in the absence of alpha beta T cells. The Journal Of Immunology 1996, 156: 4041-9. PMID: 8621947, DOI: 10.4049/jimmunol.156.10.4041.Peer-Reviewed Original ResearchConceptsAlpha beta T cellsT cell-dependent mechanismBeta T cellsCell-dependent mechanismT cellsMurine lupusHuman systemic lupus erythematosusLupus-prone MRL miceSystemic lupus erythematosusSystemic autoimmune diseaseLupus erythematosusAutoimmune diseasesImmune depositsMRL miceAlpha betaLupusDiseaseMiceCellsErythematosusHypergammaglobulinemiaAutoantibodiesCD4AutoimmunityKidney
1994
Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells
Wen L, Roberts S, Viney J, Wong F, Mallick C, Findly R, Peng Q, Craft J, Owen M, Mayday A. Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells. Nature 1994, 369: 654-658. PMID: 8208291, DOI: 10.1038/369654a0.Peer-Reviewed Original ResearchConceptsΑβ T cellsT cellsT cell antigen receptorB cell-T cell interactionsHelp of CD4Provision of cytokinesB cell hyperactivitySystemic lupus erythematosusCognate B cell-T cell interactionT cell functionGeneralized autoimmunityLupus erythematosusTransplant rejectionIgE secretionImmunoglobulin synthesisB cellsIgG3 secretionAntigen receptorCD4AutoimmunityMiceSecretionAntibodiesCellsErythematosus