2021
Cardiac allograft vasculopathy: current review and future research directions
Pober JS, Chih S, Kobashigawa J, Madsen JC, Tellides G. Cardiac allograft vasculopathy: current review and future research directions. Cardiovascular Research 2021, 117: 2624-2638. PMID: 34343276, PMCID: PMC8783389, DOI: 10.1093/cvr/cvab259.Peer-Reviewed Original ResearchConceptsCardiac allograft vasculopathyAllograft vasculopathyImmune-mediated vasculopathyLate graft lossGraft lossCardiac transplantationOrgan graftsTransplanted heartsCurrent therapiesVascular remodellingVasculopathyMajor causeCurrent reviewRemodellingTransplantationPathogenesisGraftTherapyPerfusionIncidenceDiagnosisVasculature
1997
Vascular cells have limited capacities to activate and differentiate T cells: Implications for transplant vascular sclerosis
Pober J, Ma W, Biedermann B, Libby P. Vascular cells have limited capacities to activate and differentiate T cells: Implications for transplant vascular sclerosis. Transplant Immunology 1997, 5: 251-254. PMID: 9504143, DOI: 10.1016/s0966-3274(97)80004-4.Peer-Reviewed Original Research
1992
Immunopathology of coronary arteriosclerosis in transplanted hearts.
Libby P, Swanson SJ, Tanaka H, Murray A, Schoen FJ, Pober JS. Immunopathology of coronary arteriosclerosis in transplanted hearts. The Journal Of Heart And Lung Transplantation 1992, 11: s5-6. PMID: 1622999.Peer-Reviewed Original ResearchCoronary Artery DiseaseHeart TransplantationHumansPostoperative ComplicationsTransplantation Immunology
1991
Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells.
Salomon RN, Hughes CC, Schoen FJ, Payne DD, Pober JS, Libby P. Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells. American Journal Of Pathology 1991, 138: 791-8. PMID: 2012171, PMCID: PMC1886118.Peer-Reviewed Original ResearchMeSH KeywordsCD4 AntigensCoronary Artery DiseaseCoronary VesselsEndothelium, VascularHeart TransplantationHLA AntigensHumansImmune SystemMuscle, Smooth, VascularT-LymphocytesConceptsHuman cardiac allograftsCoronary arteryT lymphocytesCardiac allograftsEndothelial cellsT cellsChronic immune reactionsDonor coronary arteriesRecipient T lymphocytesRegional immune responsesClass II major histocompatibility complexGraft endothelial cellsSmooth muscle cell proliferationAllogeneic T cellsAbility of HLAHuman arteriesLong-term survivalMuscle cell proliferationCoronary arterial endotheliumMajor histocompatibility complexNormal human arteriesTypical atherosclerosisOcclusive diseaseHLA-DRTransplanted heartsArteriosclerosis in transplanted hearts: too much and too soon.
Libby P, Pober JS, Swanson SJ, Mudge GH, Schoen FJ. Arteriosclerosis in transplanted hearts: too much and too soon. Canadian Journal Of Cardiology 1991, 7: xi-xii. PMID: 2044011.Peer-Reviewed Original Research
1989
Functions of vascular wall cells related to development of transplantation-associated coronary arteriosclerosis.
Libby P, Salomon RN, Payne DD, Schoen FJ, Pober JS. Functions of vascular wall cells related to development of transplantation-associated coronary arteriosclerosis. Transplantation Proceedings 1989, 21: 3677-84. PMID: 2669279.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCoronary Artery DiseaseCoronary VesselsHeart TransplantationHumansTransplantation ImmunologyTransplantation, HomologousConceptsArterial diseaseT cellsVascular cellsChronic immune reactionsTransplantation-associated arteriosclerosisTypical acute rejectionDelayed-type hypersensitivityHelper T cellsWall cellsClass II HLACytolytic T cellsVascular wall cellsClass I HLAVessel wall cellsUnderstanding of atherogenesisAcute rejectionGraft arteryCoronary arteriosclerosisCoronary atherosclerosisBasic pathobiologyCellular immunityImmune activationSelective therapeutic strategiesCoronary circulationAccelerated disease