2021
Differential inflammatory responses of the native left and right ventricle associated with donor heart preservation
Lei I, Huang W, Ward PA, Pober JS, Tellides G, Ailawadi G, Pagani FD, Landstrom AP, Wang Z, Mortensen RM, Cascalho M, Platt J, Chen Y, Lam HYK, Tang PC. Differential inflammatory responses of the native left and right ventricle associated with donor heart preservation. Physiological Reports 2021, 9: e15004. PMID: 34435466, PMCID: PMC8387788, DOI: 10.14814/phy2.15004.Peer-Reviewed Original ResearchConceptsRight ventricleCold ischemiaIL-10Inflammatory responseIL-6 protein levelsCold ischemic preservationEx vivo ischemiaLeft ventricle dysfunctionCold ischemic timeDonor heart preservationInflammatory cytokine expressionCell deathDifferential inflammatory responseTumor necrosis factorComparable inflammatory responsesHuman donor heartsCaspase-3 expressionIschemic preservationVentricle dysfunctionInflammasome expressionIschemic timeRNA sequencingContractile dysfunctionDonor heartsWarm perfusion
1995
Prdictive Value Of Inducible Endothelial Cell Adhesion Molecule Expression For Acte Rejection Of Human Cardiac Allografts
Briscoe DM, Yeung AC, Schoen FJ, Allred EN, Stavrakis G, Ganz P, Cotran RS, Pober JS, Schoen EL. Prdictive Value Of Inducible Endothelial Cell Adhesion Molecule Expression For Acte Rejection Of Human Cardiac Allografts. Transplantation 1995, 59: 204-211. PMID: 7530872, DOI: 10.1097/00007890-199501000-00009.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultBiopsyCD3 ComplexCell Adhesion MoleculesE-SelectinGraft RejectionHeart TransplantationHumansIntercellular Adhesion Molecule-1Longitudinal StudiesMiddle AgedMyocardial IschemiaMyocardiumPredictive Value of TestsProspective StudiesT-LymphocytesVascular Cell Adhesion Molecule-1ConceptsVascular cell adhesion molecule-1Intercellular adhesion molecule-1T-cell infiltratesHuman cardiac allograftsAdhesion molecule expressionVCAM-1 expressionAdhesion molecule-1E-selectinCardiac allograftsCell infiltrateIschemic injuryMolecule expressionEndothelial adhesion molecules intercellular adhesion molecule-1Molecule-1Adhesion molecule intercellular adhesion molecule-1Lesser extent VCAM-1Endothelial cell adhesion molecule expressionEndothelial adhesion molecule expressionAdhesion moleculesCell adhesion molecule-1Ongoing acute rejectionSuccessful antirejection therapyCardiac allograft rejectionHuman transplant recipientsImmediate posttransplant period